5C7I

Mouse sperm Glyceraldehyde-3-phosphate dehydrogenase: apo enzyme

Functional Information from GO Data

Chain	GOid	namespace	contents
O	0006006	biological_process	glucose metabolic process
O	0016620	molecular_function	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
O	0050661	molecular_function	NADP binding
O	0051287	molecular_function	NAD binding
R	0006006	biological_process	glucose metabolic process
R	0016620	molecular_function	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
R	0050661	molecular_function	NADP binding
R	0051287	molecular_function	NAD binding

Functional Information from PROSITE/UniProt

site_id	PS00071
Number of Residues	8
Details	GAPDH Glyceraldehyde 3-phosphate dehydrogenase active site. ASCTTNcL

Chain	Residue	Details
O	ALA254-LEU261

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	ACT_SITE: Nucleophile => ECO:0000255|PROSITE-ProRule:PRU10009

Chain	Residue	Details
O	CSD256
R	CSD256

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site_id	SWS_FT_FI2
Number of Residues	20
Details	BINDING: BINDING => ECO:0000250

Chain	Residue	Details
O	ARG117
O	ASN420
R	ARG117
R	ASP138
R	LYS183
R	TYR205
R	THR225
R	SER255
R	THR286
R	THR315
R	ARG338
O	ASP138
R	ASN420
O	LYS183
O	TYR205
O	THR225
O	SER255
O	THR286
O	THR315
O	ARG338

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site_id	SWS_FT_FI3
Number of Residues	2
Details	SITE: Activates thiol group during catalysis => ECO:0000250

Chain	Residue	Details
O	HIS283
R	HIS283

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site_id	SWS_FT_FI4
Number of Residues	2
Details	MOD_RES: Phosphoserine => ECO:0000250|UniProtKB:Q9ESV6

Chain	Residue	Details
O	SER358
R	SER358

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