5C6E
Joint X-ray/neutron structure of equine cyanomet hemoglobin in R state
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005344 | molecular_function | oxygen carrier activity |
| A | 0005833 | cellular_component | hemoglobin complex |
| A | 0015671 | biological_process | oxygen transport |
| A | 0020037 | molecular_function | heme binding |
| A | 0031838 | cellular_component | haptoglobin-hemoglobin complex |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0048821 | biological_process | erythrocyte development |
| B | 0005344 | molecular_function | oxygen carrier activity |
| B | 0005833 | cellular_component | hemoglobin complex |
| B | 0015671 | biological_process | oxygen transport |
| B | 0020037 | molecular_function | heme binding |
| B | 0031721 | molecular_function | hemoglobin alpha binding |
| B | 0031838 | cellular_component | haptoglobin-hemoglobin complex |
| B | 0046872 | molecular_function | metal ion binding |
| B | 0048821 | biological_process | erythrocyte development |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 16 |
| Details | binding site for residue HEM A 201 |
| Chain | Residue |
| A | TYR42 |
| A | ASN97 |
| A | LEU101 |
| A | LEU136 |
| A | CYN202 |
| A | DOD302 |
| A | DOD319 |
| A | DOD331 |
| A | PHE43 |
| A | HIS45 |
| A | HIS58 |
| A | LYS61 |
| A | LEU86 |
| A | HIS87 |
| A | LEU91 |
| A | VAL93 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | binding site for residue CYN A 202 |
| Chain | Residue |
| A | LEU29 |
| A | HIS58 |
| A | VAL62 |
| A | HEM201 |
| site_id | AC3 |
| Number of Residues | 10 |
| Details | binding site for residue HEM B 201 |
| Chain | Residue |
| B | PHE41 |
| B | PHE42 |
| B | HIS63 |
| B | SER70 |
| B | PHE71 |
| B | HIS92 |
| B | LEU96 |
| B | ASN102 |
| B | LEU141 |
| B | CYN202 |
| site_id | AC4 |
| Number of Residues | 3 |
| Details | binding site for residue CYN B 202 |
| Chain | Residue |
| B | HIS63 |
| B | VAL67 |
| B | HEM201 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | BINDING: distal binding residue => ECO:0000250|UniProtKB:P80044 |
| Chain | Residue | Details |
| B | HIS63 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | BINDING: proximal binding residue => ECO:0000269|PubMed:561852, ECO:0007744|PDB:1G0B, ECO:0007744|PDB:1IBE, ECO:0007744|PDB:1IWH, ECO:0007744|PDB:1NS6, ECO:0007744|PDB:1NS9, ECO:0007744|PDB:1Y8H, ECO:0007744|PDB:1Y8I, ECO:0007744|PDB:1Y8K, ECO:0007744|PDB:2D5X, ECO:0007744|PDB:2DHB, ECO:0007744|PDB:2MHB, ECO:0007744|PDB:2ZLT, ECO:0007744|PDB:2ZLU, ECO:0007744|PDB:2ZLV, ECO:0007744|PDB:2ZLW, ECO:0007744|PDB:2ZLX |
| Chain | Residue | Details |
| B | HIS92 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | MOD_RES: N-acetylvaline => ECO:0000250|UniProtKB:P02086 |
| Chain | Residue | Details |
| B | VAL1 | |
| A | SER49 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | MOD_RES: Phosphoserine => ECO:0000250|UniProtKB:P68871 |
| Chain | Residue | Details |
| B | SER44 | |
| A | LYS11 | |
| A | LYS40 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 3 |
| Details | MOD_RES: N6-acetyllysine => ECO:0000250|UniProtKB:P68871 |
| Chain | Residue | Details |
| B | LYS59 | |
| B | LYS82 | |
| B | LYS144 |
| site_id | SWS_FT_FI6 |
| Number of Residues | 1 |
| Details | MOD_RES: S-nitrosocysteine => ECO:0000250|UniProtKB:P68871 |
| Chain | Residue | Details |
| B | CYS93 |
| site_id | SWS_FT_FI7 |
| Number of Residues | 1 |
| Details | MOD_RES: Phosphotyrosine => ECO:0000250|UniProtKB:P69905 |
| Chain | Residue | Details |
| A | TYR24 |
| site_id | SWS_FT_FI8 |
| Number of Residues | 4 |
| Details | MOD_RES: Phosphoserine => ECO:0000250|UniProtKB:P01942 |
| Chain | Residue | Details |
| A | SER102 | |
| A | SER124 | |
| A | SER131 | |
| A | SER138 |
| site_id | SWS_FT_FI9 |
| Number of Residues | 3 |
| Details | MOD_RES: Phosphothreonine => ECO:0000250|UniProtKB:P01942 |
| Chain | Residue | Details |
| A | THR108 | |
| A | THR134 | |
| A | THR137 |
