5C5S
Crystal Structure of human Myosin 9b RhoGAP domain at 2.2 angstrom
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000146 | molecular_function | microfilament motor activity |
| A | 0005096 | molecular_function | GTPase activator activity |
| A | 0007165 | biological_process | signal transduction |
| A | 0035556 | biological_process | intracellular signal transduction |
| B | 0000146 | molecular_function | microfilament motor activity |
| B | 0005096 | molecular_function | GTPase activator activity |
| B | 0007165 | biological_process | signal transduction |
| B | 0035556 | biological_process | intracellular signal transduction |
| C | 0000146 | molecular_function | microfilament motor activity |
| C | 0005096 | molecular_function | GTPase activator activity |
| C | 0007165 | biological_process | signal transduction |
| C | 0035556 | biological_process | intracellular signal transduction |
| D | 0000146 | molecular_function | microfilament motor activity |
| D | 0005096 | molecular_function | GTPase activator activity |
| D | 0007165 | biological_process | signal transduction |
| D | 0035556 | biological_process | intracellular signal transduction |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 370 |
| Details | Domain: {"description":"Rho-GAP","evidences":[{"source":"PROSITE-ProRule","id":"PRU00172","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 20 |
| Details | Region: {"description":"Interaction with RHOA","evidences":[{"source":"PubMed","id":"26529257","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 4 |
| Details | Site: {"description":"Arginine finger; crucial for GTP hydrolysis by stabilizing the transition state","evidences":[{"source":"PROSITE-ProRule","id":"PRU00172","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
