5C3S

Crystal structure of the full-length Neurospora crassa T7H in complex with alpha-KG and 5-formyluracil (5fU)

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0016491	molecular_function	oxidoreductase activity
A	0044283	biological_process	small molecule biosynthetic process
A	0046872	molecular_function	metal ion binding
A	0051213	molecular_function	dioxygenase activity
B	0016491	molecular_function	oxidoreductase activity
B	0044283	biological_process	small molecule biosynthetic process
B	0046872	molecular_function	metal ion binding
B	0051213	molecular_function	dioxygenase activity
C	0016491	molecular_function	oxidoreductase activity
C	0044283	biological_process	small molecule biosynthetic process
C	0046872	molecular_function	metal ion binding
C	0051213	molecular_function	dioxygenase activity
D	0016491	molecular_function	oxidoreductase activity
D	0044283	biological_process	small molecule biosynthetic process
D	0046872	molecular_function	metal ion binding
D	0051213	molecular_function	dioxygenase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	binding site for residue NI A 401

Chain	Residue
A	HIS214
A	ASP216
A	HIS271
A	AKG402
A	HOH501

---

site_id	AC2
Number of Residues	15
Details	binding site for residue AKG A 402

Chain	Residue
A	ASP216
A	LEU223
A	HIS271
A	VAL273
A	ARG286
A	SER288
A	PHE292
A	NI401
A	FYU403
A	HOH501
A	HOH643
A	ARG190
A	LEU192
A	TYR194
A	HIS214

---

site_id	AC3
Number of Residues	10
Details	binding site for residue FYU A 403

Chain	Residue
A	ASN87
A	ARG190
A	HIS214
A	ASP216
A	TYR217
A	PHE292
A	AKG402
A	HOH513
A	HOH514
A	HOH557

---

site_id	AC4
Number of Residues	5
Details	binding site for residue NI B 401

Chain	Residue
B	HIS214
B	ASP216
B	HIS271
B	AKG402
B	HOH540

---

site_id	AC5
Number of Residues	14
Details	binding site for residue AKG B 402

Chain	Residue
B	ARG190
B	LEU192
B	TYR194
B	HIS214
B	ASP216
B	LEU223
B	HIS271
B	VAL273
B	ARG286
B	SER288
B	PHE292
B	NI401
B	FYU404
B	HOH540

---

site_id	AC6
Number of Residues	7
Details	binding site for residue EDO B 403

Chain	Residue
B	THR42
B	ALA43
B	PRO236
B	LYS267
B	THR269
B	HOH501
B	HOH505

---

site_id	AC7
Number of Residues	9
Details	binding site for residue FYU B 404

Chain	Residue
B	ASN87
B	ARG190
B	ASP216
B	TYR217
B	PHE292
B	AKG402
B	HOH530
B	HOH558
B	HOH619

---

site_id	AC8
Number of Residues	5
Details	binding site for residue NI C 401

Chain	Residue
C	HIS214
C	ASP216
C	HIS271
C	AKG402
C	HOH505

---

site_id	AC9
Number of Residues	14
Details	binding site for residue AKG C 402

Chain	Residue
C	ARG190
C	LEU192
C	TYR194
C	HIS214
C	ASP216
C	LEU223
C	HIS271
C	VAL273
C	ARG286
C	SER288
C	PHE292
C	NI401
C	FYU404
C	HOH505

---

site_id	AD1
Number of Residues	7
Details	binding site for residue EDO C 403

Chain	Residue
C	THR42
C	LYS234
C	SER235
C	LYS267
C	THR269
C	HOH552
C	HOH598

---

site_id	AD2
Number of Residues	9
Details	binding site for residue FYU C 404

Chain	Residue
C	HOH576
C	ASN87
C	ARG190
C	HIS214
C	ASP216
C	TYR217
C	PHE292
C	AKG402
C	HOH511

---

site_id	AD3
Number of Residues	5
Details	binding site for residue NI D 401

Chain	Residue
D	HIS214
D	ASP216
D	HIS271
D	AKG402
D	HOH508

---

site_id	AD4
Number of Residues	15
Details	binding site for residue AKG D 402

Chain	Residue
D	ARG190
D	TYR194
D	HIS214
D	ASP216
D	LEU223
D	LEU231
D	HIS271
D	VAL273
D	ARG286
D	SER288
D	PHE292
D	NI401
D	FYU404
D	HOH508
D	HOH530

---

site_id	AD5
Number of Residues	7
Details	binding site for residue EDO D 403

Chain	Residue
D	THR42
D	LYS234
D	SER235
D	PRO236
D	LYS267
D	THR269
D	HOH556

---

site_id	AD6
Number of Residues	8
Details	binding site for residue FYU D 404

Chain	Residue
D	ASN87
D	ARG190
D	HIS214
D	ASP216
D	TYR217
D	PHE292
D	AKG402
D	HOH509

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