5C3S
Crystal structure of the full-length Neurospora crassa T7H in complex with alpha-KG and 5-formyluracil (5fU)
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0044283 | biological_process | small molecule biosynthetic process |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0051213 | molecular_function | dioxygenase activity |
| A | 1901362 | biological_process | organic cyclic compound biosynthetic process |
| B | 0044283 | biological_process | small molecule biosynthetic process |
| B | 0046872 | molecular_function | metal ion binding |
| B | 0051213 | molecular_function | dioxygenase activity |
| B | 1901362 | biological_process | organic cyclic compound biosynthetic process |
| C | 0044283 | biological_process | small molecule biosynthetic process |
| C | 0046872 | molecular_function | metal ion binding |
| C | 0051213 | molecular_function | dioxygenase activity |
| C | 1901362 | biological_process | organic cyclic compound biosynthetic process |
| D | 0044283 | biological_process | small molecule biosynthetic process |
| D | 0046872 | molecular_function | metal ion binding |
| D | 0051213 | molecular_function | dioxygenase activity |
| D | 1901362 | biological_process | organic cyclic compound biosynthetic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | binding site for residue NI A 401 |
| Chain | Residue |
| A | HIS214 |
| A | ASP216 |
| A | HIS271 |
| A | AKG402 |
| A | HOH501 |
| site_id | AC2 |
| Number of Residues | 15 |
| Details | binding site for residue AKG A 402 |
| Chain | Residue |
| A | ASP216 |
| A | LEU223 |
| A | HIS271 |
| A | VAL273 |
| A | ARG286 |
| A | SER288 |
| A | PHE292 |
| A | NI401 |
| A | FYU403 |
| A | HOH501 |
| A | HOH643 |
| A | ARG190 |
| A | LEU192 |
| A | TYR194 |
| A | HIS214 |
| site_id | AC3 |
| Number of Residues | 10 |
| Details | binding site for residue FYU A 403 |
| Chain | Residue |
| A | ASN87 |
| A | ARG190 |
| A | HIS214 |
| A | ASP216 |
| A | TYR217 |
| A | PHE292 |
| A | AKG402 |
| A | HOH513 |
| A | HOH514 |
| A | HOH557 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | binding site for residue NI B 401 |
| Chain | Residue |
| B | HIS214 |
| B | ASP216 |
| B | HIS271 |
| B | AKG402 |
| B | HOH540 |
| site_id | AC5 |
| Number of Residues | 14 |
| Details | binding site for residue AKG B 402 |
| Chain | Residue |
| B | ARG190 |
| B | LEU192 |
| B | TYR194 |
| B | HIS214 |
| B | ASP216 |
| B | LEU223 |
| B | HIS271 |
| B | VAL273 |
| B | ARG286 |
| B | SER288 |
| B | PHE292 |
| B | NI401 |
| B | FYU404 |
| B | HOH540 |
| site_id | AC6 |
| Number of Residues | 7 |
| Details | binding site for residue EDO B 403 |
| Chain | Residue |
| B | THR42 |
| B | ALA43 |
| B | PRO236 |
| B | LYS267 |
| B | THR269 |
| B | HOH501 |
| B | HOH505 |
| site_id | AC7 |
| Number of Residues | 9 |
| Details | binding site for residue FYU B 404 |
| Chain | Residue |
| B | ASN87 |
| B | ARG190 |
| B | ASP216 |
| B | TYR217 |
| B | PHE292 |
| B | AKG402 |
| B | HOH530 |
| B | HOH558 |
| B | HOH619 |
| site_id | AC8 |
| Number of Residues | 5 |
| Details | binding site for residue NI C 401 |
| Chain | Residue |
| C | HIS214 |
| C | ASP216 |
| C | HIS271 |
| C | AKG402 |
| C | HOH505 |
| site_id | AC9 |
| Number of Residues | 14 |
| Details | binding site for residue AKG C 402 |
| Chain | Residue |
| C | ARG190 |
| C | LEU192 |
| C | TYR194 |
| C | HIS214 |
| C | ASP216 |
| C | LEU223 |
| C | HIS271 |
| C | VAL273 |
| C | ARG286 |
| C | SER288 |
| C | PHE292 |
| C | NI401 |
| C | FYU404 |
| C | HOH505 |
| site_id | AD1 |
| Number of Residues | 7 |
| Details | binding site for residue EDO C 403 |
| Chain | Residue |
| C | THR42 |
| C | LYS234 |
| C | SER235 |
| C | LYS267 |
| C | THR269 |
| C | HOH552 |
| C | HOH598 |
| site_id | AD2 |
| Number of Residues | 9 |
| Details | binding site for residue FYU C 404 |
| Chain | Residue |
| C | HOH576 |
| C | ASN87 |
| C | ARG190 |
| C | HIS214 |
| C | ASP216 |
| C | TYR217 |
| C | PHE292 |
| C | AKG402 |
| C | HOH511 |
| site_id | AD3 |
| Number of Residues | 5 |
| Details | binding site for residue NI D 401 |
| Chain | Residue |
| D | HIS214 |
| D | ASP216 |
| D | HIS271 |
| D | AKG402 |
| D | HOH508 |
| site_id | AD4 |
| Number of Residues | 15 |
| Details | binding site for residue AKG D 402 |
| Chain | Residue |
| D | ARG190 |
| D | TYR194 |
| D | HIS214 |
| D | ASP216 |
| D | LEU223 |
| D | LEU231 |
| D | HIS271 |
| D | VAL273 |
| D | ARG286 |
| D | SER288 |
| D | PHE292 |
| D | NI401 |
| D | FYU404 |
| D | HOH508 |
| D | HOH530 |
| site_id | AD5 |
| Number of Residues | 7 |
| Details | binding site for residue EDO D 403 |
| Chain | Residue |
| D | THR42 |
| D | LYS234 |
| D | SER235 |
| D | PRO236 |
| D | LYS267 |
| D | THR269 |
| D | HOH556 |
| site_id | AD6 |
| Number of Residues | 8 |
| Details | binding site for residue FYU D 404 |
| Chain | Residue |
| D | ASN87 |
| D | ARG190 |
| D | HIS214 |
| D | ASP216 |
| D | TYR217 |
| D | PHE292 |
| D | AKG402 |
| D | HOH509 |
