Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | binding site for residue NI A 401 |
| Chain | Residue |
| A | HIS214 |
| A | ASP216 |
| A | HIS271 |
| A | AKG402 |
| A | HOH503 |
| site_id | AC2 |
| Number of Residues | 15 |
| Details | binding site for residue AKG A 402 |
| Chain | Residue |
| A | ASP216 |
| A | LEU223 |
| A | HIS271 |
| A | VAL273 |
| A | ARG286 |
| A | SER288 |
| A | PHE292 |
| A | NI401 |
| A | HOH503 |
| A | HOH640 |
| A | HOH641 |
| A | ARG190 |
| A | LEU192 |
| A | TYR194 |
| A | HIS214 |
| site_id | AC3 |
| Number of Residues | 8 |
| Details | binding site for residue TDR A 403 |
| Chain | Residue |
| A | ASN87 |
| A | ARG190 |
| A | ASP216 |
| A | TYR217 |
| A | PHE292 |
| A | HOH515 |
| A | HOH530 |
| A | HOH555 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | binding site for residue EDO A 404 |
| Chain | Residue |
| A | THR42 |
| A | PRO236 |
| A | THR269 |
| A | HOH512 |
| A | HOH514 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | binding site for residue EDO A 405 |
| Chain | Residue |
| A | TRP81 |
| A | SER91 |
| A | GLU122 |
| A | ARG190 |
| A | HOH531 |
| site_id | AC6 |
| Number of Residues | 3 |
| Details | binding site for residue EDO A 406 |
| Chain | Residue |
| A | TYR324 |
| A | GLN327 |
| B | GLU317 |
| site_id | AC7 |
| Number of Residues | 5 |
| Details | binding site for residue EDO A 407 |
| Chain | Residue |
| A | ARG260 |
| B | ARG260 |
| B | TYR316 |
| B | GLU317 |
| B | HOH572 |
| site_id | AC8 |
| Number of Residues | 4 |
| Details | binding site for residue EDO A 408 |
| Chain | Residue |
| A | ILE51 |
| A | ILE53 |
| A | ARG58 |
| A | HOH509 |
| site_id | AC9 |
| Number of Residues | 5 |
| Details | binding site for residue NI B 401 |
| Chain | Residue |
| B | HIS214 |
| B | ASP216 |
| B | HIS271 |
| B | AKG402 |
| B | HOH516 |
| site_id | AD1 |
| Number of Residues | 15 |
| Details | binding site for residue AKG B 402 |
| Chain | Residue |
| B | ARG190 |
| B | LEU192 |
| B | TYR194 |
| B | HIS214 |
| B | ASP216 |
| B | LEU223 |
| B | HIS271 |
| B | VAL273 |
| B | ARG286 |
| B | SER288 |
| B | PHE292 |
| B | NI401 |
| B | HOH504 |
| B | HOH516 |
| B | HOH613 |
| site_id | AD2 |
| Number of Residues | 8 |
| Details | binding site for residue TDR B 403 |
| Chain | Residue |
| B | ASN87 |
| B | ARG190 |
| B | ASP216 |
| B | TYR217 |
| B | PHE292 |
| B | HOH518 |
| B | HOH523 |
| B | HOH538 |
| site_id | AD3 |
| Number of Residues | 7 |
| Details | binding site for residue EDO B 404 |
| Chain | Residue |
| B | THR42 |
| B | ALA43 |
| B | PRO236 |
| B | LYS267 |
| B | THR269 |
| B | HOH501 |
| B | HOH548 |
| site_id | AD4 |
| Number of Residues | 7 |
| Details | binding site for residue EDO B 405 |
| Chain | Residue |
| A | PRO236 |
| A | ASN237 |
| B | GLY10 |
| B | LEU11 |
| B | VAL12 |
| B | THR42 |
| B | PRO236 |
| site_id | AD5 |
| Number of Residues | 7 |
| Details | binding site for residue EDO B 406 |
| Chain | Residue |
| A | GLU213 |
| A | HIS214 |
| A | THR215 |
| A | VAL270 |
| B | GLU313 |
| B | HOH505 |
| B | HOH511 |
| site_id | AD6 |
| Number of Residues | 2 |
| Details | binding site for residue EDO B 407 |
| Chain | Residue |
| B | ASP174 |
| B | PRO305 |
| site_id | AD7 |
| Number of Residues | 5 |
| Details | binding site for residue EDO B 408 |
| Chain | Residue |
| A | ARG314 |
| A | TYR316 |
| A | GLU317 |
| B | TYR324 |
| B | GLN327 |
| site_id | AD8 |
| Number of Residues | 4 |
| Details | binding site for residue EDO B 409 |
| Chain | Residue |
| B | GLN232 |
| B | PHE240 |
| B | ARG272 |
| B | HOH582 |
| site_id | AD9 |
| Number of Residues | 5 |
| Details | binding site for residue NI C 401 |
| Chain | Residue |
| C | HIS214 |
| C | ASP216 |
| C | HIS271 |
| C | AKG402 |
| C | HOH504 |
| site_id | AE1 |
| Number of Residues | 14 |
| Details | binding site for residue AKG C 402 |
| Chain | Residue |
| C | ARG190 |
| C | LEU192 |
| C | TYR194 |
| C | HIS214 |
| C | ASP216 |
| C | LEU223 |
| C | LEU231 |
| C | HIS271 |
| C | VAL273 |
| C | ARG286 |
| C | SER288 |
| C | PHE292 |
| C | NI401 |
| C | HOH504 |
| site_id | AE2 |
| Number of Residues | 7 |
| Details | binding site for residue TDR C 403 |
| Chain | Residue |
| C | ASN87 |
| C | ARG190 |
| C | ASP216 |
| C | TYR217 |
| C | PHE292 |
| C | HOH505 |
| C | HOH533 |
| site_id | AE3 |
| Number of Residues | 5 |
| Details | binding site for residue EDO C 404 |
| Chain | Residue |
| C | LYS234 |
| C | SER235 |
| C | THR269 |
| C | HOH511 |
| C | HOH537 |
| site_id | AE4 |
| Number of Residues | 2 |
| Details | binding site for residue EDO C 405 |
| Chain | Residue |
| C | ARG260 |
| C | GLU317 |
| site_id | AE5 |
| Number of Residues | 5 |
| Details | binding site for residue NI D 401 |
| Chain | Residue |
| D | HIS214 |
| D | ASP216 |
| D | HIS271 |
| D | AKG402 |
| D | HOH506 |
| site_id | AE6 |
| Number of Residues | 14 |
| Details | binding site for residue AKG D 402 |
| Chain | Residue |
| D | ARG190 |
| D | LEU192 |
| D | TYR194 |
| D | HIS214 |
| D | ASP216 |
| D | LEU223 |
| D | HIS271 |
| D | VAL273 |
| D | ARG286 |
| D | SER288 |
| D | PHE292 |
| D | NI401 |
| D | HOH506 |
| D | HOH577 |
| site_id | AE7 |
| Number of Residues | 7 |
| Details | binding site for residue TDR D 403 |
| Chain | Residue |
| D | ASN87 |
| D | ARG190 |
| D | ASP216 |
| D | TYR217 |
| D | PHE292 |
| D | HOH508 |
| D | HOH537 |
| site_id | AE8 |
| Number of Residues | 3 |
| Details | binding site for residue EDO D 404 |
| Chain | Residue |
| D | GLU8 |
| D | PHE240 |
| D | ASP242 |
| site_id | AE9 |
| Number of Residues | 5 |
| Details | binding site for residue EDO D 405 |
| Chain | Residue |
| D | LYS234 |
| D | SER235 |
| D | THR269 |
| D | HOH551 |
| D | HOH586 |
| site_id | AF1 |
| Number of Residues | 4 |
| Details | binding site for residue EDO D 406 |
| Chain | Residue |
| D | GLU302 |
| D | ALA303 |
| D | ARG314 |
| D | HOH511 |
