5C3P
Crystal structure of the full-length Neurospora crassa T7H in complex with alpha-KG
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0044283 | biological_process | small molecule biosynthetic process |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0051213 | molecular_function | dioxygenase activity |
| A | 1901362 | biological_process | organic cyclic compound biosynthetic process |
| B | 0044283 | biological_process | small molecule biosynthetic process |
| B | 0046872 | molecular_function | metal ion binding |
| B | 0051213 | molecular_function | dioxygenase activity |
| B | 1901362 | biological_process | organic cyclic compound biosynthetic process |
| C | 0044283 | biological_process | small molecule biosynthetic process |
| C | 0046872 | molecular_function | metal ion binding |
| C | 0051213 | molecular_function | dioxygenase activity |
| C | 1901362 | biological_process | organic cyclic compound biosynthetic process |
| D | 0044283 | biological_process | small molecule biosynthetic process |
| D | 0046872 | molecular_function | metal ion binding |
| D | 0051213 | molecular_function | dioxygenase activity |
| D | 1901362 | biological_process | organic cyclic compound biosynthetic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | binding site for residue NI A 401 |
| Chain | Residue |
| A | HIS214 |
| A | ASP216 |
| A | HIS271 |
| A | AKG402 |
| A | HOH510 |
| site_id | AC2 |
| Number of Residues | 14 |
| Details | binding site for residue AKG A 402 |
| Chain | Residue |
| A | LEU223 |
| A | HIS271 |
| A | VAL273 |
| A | ARG286 |
| A | SER288 |
| A | PHE292 |
| A | NI401 |
| A | HOH504 |
| A | HOH510 |
| A | HOH529 |
| A | ARG190 |
| A | TYR194 |
| A | HIS214 |
| A | ASP216 |
| site_id | AC3 |
| Number of Residues | 3 |
| Details | binding site for residue EDO A 403 |
| Chain | Residue |
| A | ASP56 |
| A | HIS60 |
| A | ASN63 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | binding site for residue EDO A 404 |
| Chain | Residue |
| A | LYS234 |
| A | SER235 |
| A | PRO236 |
| A | THR269 |
| A | HOH531 |
| A | HOH562 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | binding site for residue EDO A 405 |
| Chain | Residue |
| A | GLU8 |
| A | ILE241 |
| A | ASP242 |
| B | ASN7 |
| site_id | AC6 |
| Number of Residues | 3 |
| Details | binding site for residue EDO A 406 |
| Chain | Residue |
| A | SER180 |
| A | ASP183 |
| A | ASN296 |
| site_id | AC7 |
| Number of Residues | 4 |
| Details | binding site for residue EDO A 407 |
| Chain | Residue |
| A | PRO245 |
| A | ILE246 |
| A | GLU247 |
| A | HOH636 |
| site_id | AC8 |
| Number of Residues | 5 |
| Details | binding site for residue EDO A 408 |
| Chain | Residue |
| A | ILE51 |
| A | ILE53 |
| A | ARG58 |
| A | ASN248 |
| A | HOH523 |
| site_id | AC9 |
| Number of Residues | 5 |
| Details | binding site for residue NI B 401 |
| Chain | Residue |
| B | HIS214 |
| B | ASP216 |
| B | HIS271 |
| B | AKG402 |
| B | HOH506 |
| site_id | AD1 |
| Number of Residues | 15 |
| Details | binding site for residue AKG B 402 |
| Chain | Residue |
| B | ARG190 |
| B | LEU192 |
| B | TYR194 |
| B | HIS214 |
| B | ASP216 |
| B | LEU223 |
| B | HIS271 |
| B | VAL273 |
| B | ARG286 |
| B | SER288 |
| B | PHE292 |
| B | NI401 |
| B | HOH506 |
| B | HOH558 |
| B | HOH577 |
| site_id | AD2 |
| Number of Residues | 6 |
| Details | binding site for residue EDO B 403 |
| Chain | Residue |
| A | ASP9 |
| A | GLY10 |
| B | SER0 |
| B | MET1 |
| B | GLU2 |
| B | HOH501 |
| site_id | AD3 |
| Number of Residues | 6 |
| Details | binding site for residue EDO B 404 |
| Chain | Residue |
| B | LYS234 |
| B | SER235 |
| B | PRO236 |
| B | THR269 |
| B | HOH527 |
| B | HOH586 |
| site_id | AD4 |
| Number of Residues | 5 |
| Details | binding site for residue NI C 401 |
| Chain | Residue |
| C | HIS214 |
| C | ASP216 |
| C | HIS271 |
| C | AKG402 |
| C | HOH527 |
| site_id | AD5 |
| Number of Residues | 13 |
| Details | binding site for residue AKG C 402 |
| Chain | Residue |
| C | ARG190 |
| C | TYR194 |
| C | HIS214 |
| C | ASP216 |
| C | LEU223 |
| C | HIS271 |
| C | VAL273 |
| C | ARG286 |
| C | SER288 |
| C | PHE292 |
| C | NI401 |
| C | HOH527 |
| C | HOH564 |
| site_id | AD6 |
| Number of Residues | 9 |
| Details | binding site for residue EDO C 403 |
| Chain | Residue |
| C | LYS267 |
| C | THR269 |
| C | HOH501 |
| C | HOH542 |
| C | THR42 |
| C | ALA43 |
| C | LYS234 |
| C | SER235 |
| C | PRO236 |
| site_id | AD7 |
| Number of Residues | 7 |
| Details | binding site for residue EDO C 404 |
| Chain | Residue |
| C | GLY229 |
| C | GLY230 |
| C | LEU231 |
| C | ASP242 |
| C | ALA243 |
| C | THR244 |
| C | PRO277 |
| site_id | AD8 |
| Number of Residues | 6 |
| Details | binding site for residue EDO C 405 |
| Chain | Residue |
| A | ASN151 |
| A | GLN155 |
| A | HOH554 |
| C | SER147 |
| C | ASP154 |
| C | HOH504 |
| site_id | AD9 |
| Number of Residues | 5 |
| Details | binding site for residue NI D 401 |
| Chain | Residue |
| D | HIS214 |
| D | ASP216 |
| D | HIS271 |
| D | AKG402 |
| D | HOH512 |
| site_id | AE1 |
| Number of Residues | 12 |
| Details | binding site for residue AKG D 402 |
| Chain | Residue |
| D | ARG190 |
| D | TYR194 |
| D | HIS214 |
| D | ASP216 |
| D | LEU223 |
| D | HIS271 |
| D | VAL273 |
| D | ARG286 |
| D | SER288 |
| D | PHE292 |
| D | NI401 |
| D | HOH512 |
| site_id | AE2 |
| Number of Residues | 3 |
| Details | binding site for residue EDO D 403 |
| Chain | Residue |
| D | GLU8 |
| D | PHE240 |
| D | ASP242 |
| site_id | AE3 |
| Number of Residues | 2 |
| Details | binding site for residue EDO D 404 |
| Chain | Residue |
| D | GLU8 |
| D | GLN239 |
| site_id | AE4 |
| Number of Residues | 5 |
| Details | binding site for residue EDO D 405 |
| Chain | Residue |
| D | LYS234 |
| D | SER235 |
| D | THR269 |
| D | HOH566 |
| D | HOH567 |
| site_id | AE5 |
| Number of Residues | 5 |
| Details | binding site for residue EDO D 406 |
| Chain | Residue |
| B | ARG260 |
| D | ARG260 |
| D | LYS315 |
| D | GLU317 |
| D | HOH557 |
