5C31

Constitutively active Sin recombinase catalytic domain reveals two rotational intermediates

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000150	molecular_function	DNA strand exchange activity
A	0003677	molecular_function	DNA binding
A	0006310	biological_process	DNA recombination
B	0000150	molecular_function	DNA strand exchange activity
B	0003677	molecular_function	DNA binding
B	0006310	biological_process	DNA recombination
C	0000150	molecular_function	DNA strand exchange activity
C	0003677	molecular_function	DNA binding
C	0006310	biological_process	DNA recombination
D	0000150	molecular_function	DNA strand exchange activity
D	0003677	molecular_function	DNA binding
D	0006310	biological_process	DNA recombination
E	0000150	molecular_function	DNA strand exchange activity
E	0003677	molecular_function	DNA binding
E	0006310	biological_process	DNA recombination
F	0000150	molecular_function	DNA strand exchange activity
F	0003677	molecular_function	DNA binding
F	0006310	biological_process	DNA recombination
G	0000150	molecular_function	DNA strand exchange activity
G	0003677	molecular_function	DNA binding
G	0006310	biological_process	DNA recombination
H	0000150	molecular_function	DNA strand exchange activity
H	0003677	molecular_function	DNA binding
H	0006310	biological_process	DNA recombination
I	0000150	molecular_function	DNA strand exchange activity
I	0003677	molecular_function	DNA binding
I	0006310	biological_process	DNA recombination
J	0000150	molecular_function	DNA strand exchange activity
J	0003677	molecular_function	DNA binding
J	0006310	biological_process	DNA recombination
K	0000150	molecular_function	DNA strand exchange activity
K	0003677	molecular_function	DNA binding
K	0006310	biological_process	DNA recombination
L	0000150	molecular_function	DNA strand exchange activity
L	0003677	molecular_function	DNA binding
L	0006310	biological_process	DNA recombination

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	binding site for residue SO4 A 201

Chain	Residue
A	ARG7
A	SER9
A	GLN13
A	ARG66
A	ARG69

---

site_id	AC2
Number of Residues	5
Details	binding site for residue SO4 B 201

Chain	Residue
B	ARG69
B	ARG7
B	SER9
B	GLN13
B	ARG66

---

site_id	AC3
Number of Residues	3
Details	binding site for residue SO4 B 202

Chain	Residue
B	GLN13
B	ASN14
B	ARG17

---

site_id	AC4
Number of Residues	5
Details	binding site for residue SO4 C 201

Chain	Residue
C	ARG7
C	SER9
C	GLN13
C	ARG66
C	ARG69

---

site_id	AC5
Number of Residues	3
Details	binding site for residue SO4 C 202

Chain	Residue
C	GLN13
C	ASN14
C	ARG17

---

site_id	AC6
Number of Residues	5
Details	binding site for residue SO4 D 201

Chain	Residue
D	ARG7
D	SER9
D	SER36
D	ARG66
D	ARG69

---

site_id	AC7
Number of Residues	5
Details	binding site for residue SO4 E 201

Chain	Residue
E	ARG7
E	SER9
E	SER36
E	ARG66
E	ARG69

---

site_id	AC8
Number of Residues	4
Details	binding site for residue SO4 F 201

Chain	Residue
F	ARG7
F	SER9
F	ARG66
F	ARG69

---

site_id	AC9
Number of Residues	4
Details	binding site for residue SO4 G 201

Chain	Residue
G	ARG7
G	SER9
G	ARG66
G	ARG69

---

site_id	AD1
Number of Residues	5
Details	binding site for residue SO4 H 201

Chain	Residue
H	ARG7
H	SER9
H	GLN13
H	ARG66
H	ARG69

---

site_id	AD2
Number of Residues	3
Details	binding site for residue SO4 H 202

Chain	Residue
H	GLN13
H	ASN14
H	ARG17

---

site_id	AD3
Number of Residues	3
Details	binding site for residue SO4 H 203

Chain	Residue
H	SER10
H	LEU11
H	LYS34

---

site_id	AD4
Number of Residues	6
Details	binding site for residue SO4 I 201

Chain	Residue
I	ARG7
I	SER9
I	GLN13
I	SER36
I	ARG66
I	ARG69

---

site_id	AD5
Number of Residues	2
Details	binding site for residue SO4 I 202

Chain	Residue
B	LYS34
I	MSE1

---

site_id	AD6
Number of Residues	3
Details	binding site for residue SO4 I 203

Chain	Residue
I	GLN87
I	LYS107
I	LYS110

---

site_id	AD7
Number of Residues	3
Details	binding site for residue SO4 I 204

Chain	Residue
I	GLN13
I	ASN14
I	ARG17

---

site_id	AD8
Number of Residues	7
Details	binding site for residue SO4 J 201

Chain	Residue
J	ARG7
J	SER9
J	GLN13
J	SER36
J	ARG66
J	ARG69
J	ARG125

---

site_id	AD9
Number of Residues	3
Details	binding site for residue SO4 J 202

Chain	Residue
J	GLN13
J	ASN14
J	ARG17

---

site_id	AE1
Number of Residues	5
Details	binding site for residue SO4 K 201

Chain	Residue
K	ARG7
K	SER9
K	SER36
K	ARG66
K	ARG69

---

site_id	AE2
Number of Residues	6
Details	binding site for residue SO4 L 201

Chain	Residue
L	ARG7
L	SER9
L	GLN13
L	SER36
L	ARG66
L	ARG69

---

site_id	AE3
Number of Residues	4
Details	binding site for residue SO4 L 202

Chain	Residue
L	GLN13
L	ASN14
L	ARG17
L	ARG66

---

Functional Information from PROSITE/UniProt

site_id	PS00397
Number of Residues	9
Details	RECOMBINASES_1 Site-specific recombinases active site. YARVSSldQ

Chain	Residue	Details
A	TYR5-GLN13

---

site_id	PS00398
Number of Residues	13
Details	RECOMBINASES_2 Site-specific recombinases signature 2. GDrfIVeSIDRLG

Chain	Residue	Details
A	GLY56-GLY68

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	12
Details	ACT_SITE: O-(5'-phospho-DNA)-serine intermediate => ECO:0000255|PROSITE-ProRule:PRU01072

Chain	Residue	Details
A	SER9
J	SER9
K	SER9
L	SER9
B	SER9
C	SER9
D	SER9
E	SER9
F	SER9
G	SER9
H	SER9
I	SER9

---