5BZB
NavMs voltage-gated sodium channel pore and C-terminal domain
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005216 | molecular_function | monoatomic ion channel activity |
| A | 0005227 | molecular_function | calcium-activated cation channel activity |
| A | 0006811 | biological_process | monoatomic ion transport |
| A | 0016020 | cellular_component | membrane |
| A | 0030317 | biological_process | flagellated sperm motility |
| A | 0036128 | cellular_component | CatSper complex |
| A | 0055085 | biological_process | transmembrane transport |
| B | 0005216 | molecular_function | monoatomic ion channel activity |
| B | 0005227 | molecular_function | calcium-activated cation channel activity |
| B | 0006811 | biological_process | monoatomic ion transport |
| B | 0016020 | cellular_component | membrane |
| B | 0030317 | biological_process | flagellated sperm motility |
| B | 0036128 | cellular_component | CatSper complex |
| B | 0055085 | biological_process | transmembrane transport |
| C | 0005216 | molecular_function | monoatomic ion channel activity |
| C | 0005227 | molecular_function | calcium-activated cation channel activity |
| C | 0006811 | biological_process | monoatomic ion transport |
| C | 0016020 | cellular_component | membrane |
| C | 0030317 | biological_process | flagellated sperm motility |
| C | 0036128 | cellular_component | CatSper complex |
| C | 0055085 | biological_process | transmembrane transport |
| D | 0005216 | molecular_function | monoatomic ion channel activity |
| D | 0005227 | molecular_function | calcium-activated cation channel activity |
| D | 0006811 | biological_process | monoatomic ion transport |
| D | 0016020 | cellular_component | membrane |
| D | 0030317 | biological_process | flagellated sperm motility |
| D | 0036128 | cellular_component | CatSper complex |
| D | 0055085 | biological_process | transmembrane transport |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | binding site for residue 12P A 301 |
| Chain | Residue |
| A | TYR153 |
| A | HIS192 |
| A | ASN194 |
| A | ALA195 |
| A | HOH406 |
| A | HOH422 |
| site_id | AC2 |
| Number of Residues | 2 |
| Details | binding site for residue NA A 302 |
| Chain | Residue |
| A | NA303 |
| A | NA303 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | binding site for residue NA A 303 |
| Chain | Residue |
| A | NA302 |
| A | HOH443 |
| A | HOH443 |
| A | NA302 |
| site_id | AC4 |
| Number of Residues | 8 |
| Details | binding site for residue NA A 304 |
| Chain | Residue |
| A | HOH440 |
| A | HOH440 |
| A | HOH443 |
| A | HOH443 |
| B | HOH417 |
| B | HOH417 |
| B | HOH452 |
| B | HOH452 |
| site_id | AC5 |
| Number of Residues | 9 |
| Details | binding site for residue 2CV B 301 |
| Chain | Residue |
| A | MET189 |
| A | PRO193 |
| A | TRP196 |
| B | GLU159 |
| B | SER165 |
| B | LYS166 |
| B | TYR169 |
| B | HOH406 |
| B | HOH415 |
| site_id | AC6 |
| Number of Residues | 8 |
| Details | binding site for residue 2CV B 302 |
| Chain | Residue |
| A | SER165 |
| A | LYS166 |
| B | MET189 |
| B | PRO193 |
| B | TRP196 |
| B | HOH404 |
| B | HOH409 |
| B | HOH418 |
| site_id | AC7 |
| Number of Residues | 5 |
| Details | binding site for residue 12P B 303 |
| Chain | Residue |
| B | TYR153 |
| B | HIS192 |
| B | VAL197 |
| B | PHE198 |
| B | HOH402 |
| site_id | AC8 |
| Number of Residues | 4 |
| Details | binding site for residue 12P C 301 |
| Chain | Residue |
| C | TYR153 |
| C | ALA195 |
| C | VAL197 |
| C | PHE198 |
| site_id | AC9 |
| Number of Residues | 6 |
| Details | binding site for residue NA C 302 |
| Chain | Residue |
| C | HOH417 |
| C | HOH417 |
| D | NA303 |
| D | NA303 |
| D | HOH415 |
| D | HOH415 |
| site_id | AD1 |
| Number of Residues | 8 |
| Details | binding site for residue NA C 303 |
| Chain | Residue |
| C | HOH423 |
| C | HOH423 |
| C | HOH435 |
| C | HOH435 |
| C | HOH437 |
| C | HOH437 |
| D | HOH435 |
| D | HOH435 |
| site_id | AD2 |
| Number of Residues | 14 |
| Details | binding site for residue 2CV D 301 |
| Chain | Residue |
| C | ARG186 |
| C | MET189 |
| C | PRO193 |
| C | ASN194 |
| C | TRP196 |
| C | HOH401 |
| D | PHE142 |
| D | GLU159 |
| D | SER165 |
| D | LYS166 |
| D | TYR169 |
| D | HOH402 |
| D | HOH411 |
| D | HOH414 |
| site_id | AD3 |
| Number of Residues | 13 |
| Details | binding site for residue 2CV D 302 |
| Chain | Residue |
| C | GLU159 |
| C | SER165 |
| C | LYS166 |
| C | TYR169 |
| D | ARG186 |
| D | MET189 |
| D | PRO193 |
| D | ASN194 |
| D | TRP196 |
| D | HOH409 |
| D | HOH412 |
| D | HOH416 |
| D | HOH419 |
| site_id | AD4 |
| Number of Residues | 6 |
| Details | binding site for residue NA D 303 |
| Chain | Residue |
| C | NA302 |
| C | NA302 |
| C | HOH417 |
| C | HOH417 |
| D | HOH415 |
| D | HOH415 |
