5BXI

1.7 Angstrom Resolution Crystal Structure of Putative Nucleoside Diphosphate Kinase from Toxoplasma gondii with Tyrosine of Tag Bound to Active Site

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004550	molecular_function	nucleoside diphosphate kinase activity
A	0005524	molecular_function	ATP binding
A	0006183	biological_process	GTP biosynthetic process
A	0006228	biological_process	UTP biosynthetic process
A	0006241	biological_process	CTP biosynthetic process
A	0009142	biological_process	nucleoside triphosphate biosynthetic process
A	0016301	molecular_function	kinase activity
B	0004550	molecular_function	nucleoside diphosphate kinase activity
B	0005524	molecular_function	ATP binding
B	0006183	biological_process	GTP biosynthetic process
B	0006228	biological_process	UTP biosynthetic process
B	0006241	biological_process	CTP biosynthetic process
B	0009142	biological_process	nucleoside triphosphate biosynthetic process
B	0016301	molecular_function	kinase activity
C	0004550	molecular_function	nucleoside diphosphate kinase activity
C	0005524	molecular_function	ATP binding
C	0006183	biological_process	GTP biosynthetic process
C	0006228	biological_process	UTP biosynthetic process
C	0006241	biological_process	CTP biosynthetic process
C	0009142	biological_process	nucleoside triphosphate biosynthetic process
C	0016301	molecular_function	kinase activity
D	0004550	molecular_function	nucleoside diphosphate kinase activity
D	0005524	molecular_function	ATP binding
D	0006183	biological_process	GTP biosynthetic process
D	0006228	biological_process	UTP biosynthetic process
D	0006241	biological_process	CTP biosynthetic process
D	0009142	biological_process	nucleoside triphosphate biosynthetic process
D	0016301	molecular_function	kinase activity
E	0004550	molecular_function	nucleoside diphosphate kinase activity
E	0005524	molecular_function	ATP binding
E	0006183	biological_process	GTP biosynthetic process
E	0006228	biological_process	UTP biosynthetic process
E	0006241	biological_process	CTP biosynthetic process
E	0009142	biological_process	nucleoside triphosphate biosynthetic process
E	0016301	molecular_function	kinase activity
F	0004550	molecular_function	nucleoside diphosphate kinase activity
F	0005524	molecular_function	ATP binding
F	0006183	biological_process	GTP biosynthetic process
F	0006228	biological_process	UTP biosynthetic process
F	0006241	biological_process	CTP biosynthetic process
F	0009142	biological_process	nucleoside triphosphate biosynthetic process
F	0016301	molecular_function	kinase activity
G	0004550	molecular_function	nucleoside diphosphate kinase activity
G	0005524	molecular_function	ATP binding
G	0006183	biological_process	GTP biosynthetic process
G	0006228	biological_process	UTP biosynthetic process
G	0006241	biological_process	CTP biosynthetic process
G	0009142	biological_process	nucleoside triphosphate biosynthetic process
G	0016301	molecular_function	kinase activity
H	0004550	molecular_function	nucleoside diphosphate kinase activity
H	0005524	molecular_function	ATP binding
H	0006183	biological_process	GTP biosynthetic process
H	0006228	biological_process	UTP biosynthetic process
H	0006241	biological_process	CTP biosynthetic process
H	0009142	biological_process	nucleoside triphosphate biosynthetic process
H	0016301	molecular_function	kinase activity
I	0004550	molecular_function	nucleoside diphosphate kinase activity
I	0005524	molecular_function	ATP binding
I	0006183	biological_process	GTP biosynthetic process
I	0006228	biological_process	UTP biosynthetic process
I	0006241	biological_process	CTP biosynthetic process
I	0009142	biological_process	nucleoside triphosphate biosynthetic process
I	0016301	molecular_function	kinase activity
J	0004550	molecular_function	nucleoside diphosphate kinase activity
J	0005524	molecular_function	ATP binding
J	0006183	biological_process	GTP biosynthetic process
J	0006228	biological_process	UTP biosynthetic process
J	0006241	biological_process	CTP biosynthetic process
J	0009142	biological_process	nucleoside triphosphate biosynthetic process
J	0016301	molecular_function	kinase activity
K	0004550	molecular_function	nucleoside diphosphate kinase activity
K	0005524	molecular_function	ATP binding
K	0006183	biological_process	GTP biosynthetic process
K	0006228	biological_process	UTP biosynthetic process
K	0006241	biological_process	CTP biosynthetic process
K	0009142	biological_process	nucleoside triphosphate biosynthetic process
K	0016301	molecular_function	kinase activity
L	0004550	molecular_function	nucleoside diphosphate kinase activity
L	0005524	molecular_function	ATP binding
L	0006183	biological_process	GTP biosynthetic process
L	0006228	biological_process	UTP biosynthetic process
L	0006241	biological_process	CTP biosynthetic process
L	0009142	biological_process	nucleoside triphosphate biosynthetic process
L	0016301	molecular_function	kinase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	7
Details	binding site for residue BCT A 201

Chain	Residue
A	LYS14
A	THR96
A	ARG107
A	ASN117
A	VAL119
A	HIS120
A	HOH363

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site_id	AC2
Number of Residues	3
Details	binding site for residue BCT B 201

Chain	Residue
B	HOH304
B	GLN6
B	ARG8

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site_id	AC3
Number of Residues	4
Details	binding site for residue BCT C 201

Chain	Residue
C	GLN6
C	ARG8
C	GLU143
C	HOH307

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site_id	AC4
Number of Residues	6
Details	binding site for residue BCT D 201

Chain	Residue
D	LYS14
D	THR96
D	ASN117
D	HIS120
D	HOH338
D	HOH423

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site_id	AC5
Number of Residues	3
Details	binding site for residue PEG D 202

Chain	Residue
D	LYS14
D	TYR54
D	LEU66

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site_id	AC6
Number of Residues	8
Details	binding site for residue BCT F 201

Chain	Residue
B	HOH459
C	GLN148
E	ARG20
E	HOH285
F	GLN148
F	HOH306
F	HOH326
F	HOH335

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site_id	AC7
Number of Residues	6
Details	binding site for residue BCT I 201

Chain	Residue
I	LYS14
I	THR96
I	ASN117
I	HIS120
I	HOH305
I	HOH325

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Functional Information from PROSITE/UniProt

site_id	PS00469
Number of Residues	9
Details	NDPK Nucleoside diphosphate kinase (NDPK) active site signature. NivHGSDSV

Chain	Residue	Details
A	ASN117-VAL125

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