Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0005829 | cellular_component | cytosol |
| A | 0016829 | molecular_function | lyase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 11 |
| Details | binding site for residue FUM A 901 |
| Chain | Residue |
| A | LEU492 |
| A | GLN707 |
| A | HOH1062 |
| A | CYS493 |
| A | MET494 |
| A | SER495 |
| A | ARG508 |
| A | GLY512 |
| A | GLY513 |
| A | TRP613 |
| A | ASN615 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | binding site for residue TRS A 902 |
| Chain | Residue |
| A | ARG46 |
| A | LYS67 |
| A | PHE115 |
| A | LYS307 |
| A | GLU361 |
| A | HOH1015 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | binding site for residue PGE A 903 |
| Chain | Residue |
| A | ASP229 |
| A | ASN243 |
| A | LYS246 |
| A | TRP250 |
| A | GLU598 |
| A | LEU599 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | binding site for residue PGE A 904 |
| Chain | Residue |
| A | ASP229 |
| A | THR232 |
| A | PRO234 |
| A | TRP235 |
| A | ASN236 |
| A | GLY240 |
| site_id | AC5 |
| Number of Residues | 7 |
| Details | binding site for residue PGE A 905 |
| Chain | Residue |
| A | LEU475 |
| A | ASN476 |
| A | ALA605 |
| A | LEU606 |
| A | SER607 |
| A | TYR697 |
| A | HOH1322 |
| site_id | AC6 |
| Number of Residues | 6 |
| Details | binding site for residue PGE A 906 |
| Chain | Residue |
| A | GLY477 |
| A | GLY479 |
| A | ALA480 |
| A | THR481 |
| A | ASP482 |
| A | HOH1234 |
| site_id | AC7 |
| Number of Residues | 5 |
| Details | binding site for residue PG4 A 907 |
| Chain | Residue |
| A | LYS84 |
| A | GLU153 |
| A | ALA156 |
| A | ILE157 |
| A | HOH1095 |
| site_id | AC8 |
| Number of Residues | 8 |
| Details | binding site for residue PGE A 908 |
| Chain | Residue |
| A | ARG143 |
| A | SER144 |
| A | ASP145 |
| A | HIS356 |
| A | LYS439 |
| A | TRP443 |
| A | GLU446 |
| A | HOH1153 |
Functional Information from PROSITE/UniProt
| site_id | PS00850 |
| Number of Residues | 9 |
| Details | GLY_RADICAL_1 Glycine radical domain signature. IvRVSGYSA |
| Chain | Residue | Details |
| A | ILE824-ALA832 | |
