5BUD

Crystal structure of Candida albicans Rai1 in complex with pU5-Mn2+

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0000448	biological_process	cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
A	0000463	biological_process	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
A	0000466	biological_process	maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
A	0000956	biological_process	nuclear-transcribed mRNA catabolic process
A	0003723	molecular_function	RNA binding
A	0004518	molecular_function	nuclease activity
A	0005634	cellular_component	nucleus
A	0005829	cellular_component	cytosol
A	0006397	biological_process	mRNA processing
A	0016787	molecular_function	hydrolase activity
A	0030234	molecular_function	enzyme regulator activity
A	0030846	biological_process	termination of RNA polymerase II transcription, poly(A)-coupled
A	0031087	biological_process	deadenylation-independent decapping of nuclear-transcribed mRNA
A	0034353	molecular_function	mRNA 5'-diphosphatase activity
A	0046872	molecular_function	metal ion binding
A	0071035	biological_process	nuclear polyadenylation-dependent rRNA catabolic process
A	0090730	cellular_component	Las1 complex
A	0110103	cellular_component	RNA polymerase II termination complex
A	0110152	molecular_function	RNA NAD+-cap (NAD+-forming) hydrolase activity
A	0110155	biological_process	NAD-cap decapping
A	1904595	biological_process	positive regulation of termination of RNA polymerase II transcription
A	1990174	molecular_function	phosphodiesterase decapping endonuclease activity
B	0000166	molecular_function	nucleotide binding
B	0000448	biological_process	cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
B	0000463	biological_process	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
B	0000466	biological_process	maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
B	0000956	biological_process	nuclear-transcribed mRNA catabolic process
B	0003723	molecular_function	RNA binding
B	0004518	molecular_function	nuclease activity
B	0005634	cellular_component	nucleus
B	0005829	cellular_component	cytosol
B	0006397	biological_process	mRNA processing
B	0016787	molecular_function	hydrolase activity
B	0030234	molecular_function	enzyme regulator activity
B	0030846	biological_process	termination of RNA polymerase II transcription, poly(A)-coupled
B	0031087	biological_process	deadenylation-independent decapping of nuclear-transcribed mRNA
B	0034353	molecular_function	mRNA 5'-diphosphatase activity
B	0046872	molecular_function	metal ion binding
B	0071035	biological_process	nuclear polyadenylation-dependent rRNA catabolic process
B	0090730	cellular_component	Las1 complex
B	0110103	cellular_component	RNA polymerase II termination complex
B	0110152	molecular_function	RNA NAD+-cap (NAD+-forming) hydrolase activity
B	0110155	biological_process	NAD-cap decapping
B	1904595	biological_process	positive regulation of termination of RNA polymerase II transcription
B	1990174	molecular_function	phosphodiesterase decapping endonuclease activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	binding site for residue MN A 401

Chain	Residue
A	ASP225
A	GLU244
A	LEU245
A	MN402
A	HOH581
D	U2

---

site_id	AC2
Number of Residues	6
Details	binding site for residue MN A 402

Chain	Residue
A	HOH599
A	HOH628
D	U2
A	GLU223
A	ASP225
A	MN401

---

site_id	AC3
Number of Residues	7
Details	binding site for residue MN A 403

Chain	Residue
A	GLU174
A	GLU223
A	HOH524
A	HOH563
A	HOH628
A	HOH737
A	HOH898

---

site_id	AC4
Number of Residues	6
Details	binding site for residue MN B 401

Chain	Residue
B	ASP225
B	GLU244
B	LEU245
B	MN402
B	HOH582
E	U2

---

site_id	AC5
Number of Residues	7
Details	binding site for residue MN B 402

Chain	Residue
B	GLU223
B	ASP225
B	MN401
B	HOH556
B	HOH610
B	HOH860
E	U2

---

site_id	AC6
Number of Residues	7
Details	binding site for residue MN B 403

Chain	Residue
B	GLU174
B	GLU223
B	HOH546
B	HOH610
B	HOH625
B	HOH863
B	HOH946

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	8
Details	Binding site: {"evidences":[{"source":"PubMed","id":"26101253","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5BTH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5BUD","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	6
Details	Binding site: {"evidences":[{"source":"UniProtKB","id":"O70348","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

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