5BSE
Crystal structure of Medicago truncatula (delta)1-Pyrroline-5-Carboxylate Reductase (MtP5CR)
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004735 | molecular_function | pyrroline-5-carboxylate reductase activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0055129 | biological_process | L-proline biosynthetic process |
| A | 1902792 | cellular_component | pyrroline-5-carboxylate reductase complex |
| B | 0004735 | molecular_function | pyrroline-5-carboxylate reductase activity |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0055129 | biological_process | L-proline biosynthetic process |
| B | 1902792 | cellular_component | pyrroline-5-carboxylate reductase complex |
| C | 0004735 | molecular_function | pyrroline-5-carboxylate reductase activity |
| C | 0005737 | cellular_component | cytoplasm |
| C | 0055129 | biological_process | L-proline biosynthetic process |
| C | 1902792 | cellular_component | pyrroline-5-carboxylate reductase complex |
| D | 0004735 | molecular_function | pyrroline-5-carboxylate reductase activity |
| D | 0005737 | cellular_component | cytoplasm |
| D | 0055129 | biological_process | L-proline biosynthetic process |
| D | 1902792 | cellular_component | pyrroline-5-carboxylate reductase complex |
| E | 0004735 | molecular_function | pyrroline-5-carboxylate reductase activity |
| E | 0005737 | cellular_component | cytoplasm |
| E | 0055129 | biological_process | L-proline biosynthetic process |
| E | 1902792 | cellular_component | pyrroline-5-carboxylate reductase complex |
| F | 0004735 | molecular_function | pyrroline-5-carboxylate reductase activity |
| F | 0005737 | cellular_component | cytoplasm |
| F | 0055129 | biological_process | L-proline biosynthetic process |
| F | 1902792 | cellular_component | pyrroline-5-carboxylate reductase complex |
| G | 0004735 | molecular_function | pyrroline-5-carboxylate reductase activity |
| G | 0005737 | cellular_component | cytoplasm |
| G | 0055129 | biological_process | L-proline biosynthetic process |
| G | 1902792 | cellular_component | pyrroline-5-carboxylate reductase complex |
| H | 0004735 | molecular_function | pyrroline-5-carboxylate reductase activity |
| H | 0005737 | cellular_component | cytoplasm |
| H | 0055129 | biological_process | L-proline biosynthetic process |
| H | 1902792 | cellular_component | pyrroline-5-carboxylate reductase complex |
| I | 0004735 | molecular_function | pyrroline-5-carboxylate reductase activity |
| I | 0005737 | cellular_component | cytoplasm |
| I | 0055129 | biological_process | L-proline biosynthetic process |
| I | 1902792 | cellular_component | pyrroline-5-carboxylate reductase complex |
| J | 0004735 | molecular_function | pyrroline-5-carboxylate reductase activity |
| J | 0005737 | cellular_component | cytoplasm |
| J | 0055129 | biological_process | L-proline biosynthetic process |
| J | 1902792 | cellular_component | pyrroline-5-carboxylate reductase complex |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 11 |
| Details | binding site for residue MPO A 301 |
| Chain | Residue |
| A | LYS80 |
| B | THR243 |
| B | CL301 |
| A | PRO81 |
| A | MET126 |
| A | GLY180 |
| A | SER181 |
| A | HOH406 |
| A | HOH537 |
| B | SER238 |
| B | THR242 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | binding site for residue CL A 302 |
| Chain | Residue |
| A | VAL236 |
| A | SER238 |
| A | THR242 |
| A | THR243 |
| A | HOH422 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | binding site for residue CL B 301 |
| Chain | Residue |
| A | MPO301 |
| B | SER238 |
| B | THR242 |
| B | THR243 |
| B | HOH440 |
| site_id | AC4 |
| Number of Residues | 8 |
| Details | binding site for residue MPO C 301 |
| Chain | Residue |
| C | PRO81 |
| C | ALA106 |
| C | MET126 |
| C | THR176 |
| C | GLY180 |
| D | SER238 |
| D | THR242 |
| D | CL301 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | binding site for residue CL C 302 |
| Chain | Residue |
| C | SER238 |
| C | THR242 |
| C | THR243 |
| C | HOH428 |
| C | HOH455 |
| site_id | AC6 |
| Number of Residues | 5 |
| Details | binding site for residue CL D 301 |
| Chain | Residue |
| C | MPO301 |
| D | SER238 |
| D | THR242 |
| D | THR243 |
| D | HOH413 |
| site_id | AC7 |
| Number of Residues | 4 |
| Details | binding site for residue CL E 301 |
| Chain | Residue |
| E | SER238 |
| E | THR242 |
| E | THR243 |
| E | HOH415 |
| site_id | AC8 |
| Number of Residues | 4 |
| Details | binding site for residue CL F 301 |
| Chain | Residue |
| F | SER238 |
| F | THR242 |
| F | THR243 |
| F | HOH423 |
| site_id | AC9 |
| Number of Residues | 5 |
| Details | binding site for residue CL G 301 |
| Chain | Residue |
| G | SER238 |
| G | THR242 |
| G | THR243 |
| G | HOH418 |
| H | MPO301 |
| site_id | AD1 |
| Number of Residues | 11 |
| Details | binding site for residue MPO H 301 |
| Chain | Residue |
| G | SER238 |
| G | THR242 |
| G | THR243 |
| G | CL301 |
| H | PRO81 |
| H | ALA106 |
| H | MET126 |
| H | THR176 |
| H | GLY180 |
| H | SER181 |
| H | HOH459 |
| site_id | AD2 |
| Number of Residues | 5 |
| Details | binding site for residue CL H 302 |
| Chain | Residue |
| H | SER238 |
| H | THR242 |
| H | THR243 |
| H | HOH463 |
| H | HOH489 |
| site_id | AD3 |
| Number of Residues | 11 |
| Details | binding site for residue MPO I 301 |
| Chain | Residue |
| I | PRO81 |
| I | ALA106 |
| I | MET126 |
| I | GLY180 |
| I | SER181 |
| I | HOH404 |
| I | HOH544 |
| J | SER238 |
| J | THR242 |
| J | THR243 |
| J | CL302 |
| site_id | AD4 |
| Number of Residues | 6 |
| Details | binding site for residue CL I 302 |
| Chain | Residue |
| I | VAL236 |
| I | SER238 |
| I | THR242 |
| I | THR243 |
| I | HOH412 |
| J | MPO301 |
| site_id | AD5 |
| Number of Residues | 12 |
| Details | binding site for residue MPO J 301 |
| Chain | Residue |
| I | SER238 |
| I | THR242 |
| I | THR243 |
| I | CL302 |
| I | HOH444 |
| J | PRO81 |
| J | GLN82 |
| J | ALA106 |
| J | MET126 |
| J | THR176 |
| J | GLY180 |
| J | SER181 |
| site_id | AD6 |
| Number of Residues | 5 |
| Details | binding site for residue CL J 302 |
| Chain | Residue |
| J | THR242 |
| J | THR243 |
| J | HOH413 |
| I | MPO301 |
| J | SER238 |
Functional Information from PROSITE/UniProt
| site_id | PS00521 |
| Number of Residues | 23 |
| Details | P5CR Delta 1-pyrroline-5-carboxylate reductase signature. Pgq.LkddVTSpGGtTiaGVheLE |
| Chain | Residue | Details |
| A | PRO229-GLU251 |
