Functional Information from GO Data
| Chain | GOid | namespace | contents |
| B | 0003677 | molecular_function | DNA binding |
| B | 0003918 | molecular_function | DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity |
| B | 0005524 | molecular_function | ATP binding |
| B | 0006259 | biological_process | DNA metabolic process |
| B | 0006265 | biological_process | DNA topological change |
| D | 0003677 | molecular_function | DNA binding |
| D | 0003918 | molecular_function | DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity |
| D | 0005524 | molecular_function | ATP binding |
| D | 0006259 | biological_process | DNA metabolic process |
| D | 0006265 | biological_process | DNA topological change |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | binding site for residue MN B 1501 |
| Chain | Residue |
| B | GLU435 |
| B | ASP508 |
| B | HOH1602 |
| B | HOH1606 |
| E | G8 |
| E | G9 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | binding site for residue MN D 1501 |
| Chain | Residue |
| D | HOH1618 |
| F | G8 |
| F | G9 |
| D | GLU435 |
| D | ASP508 |
| D | HOH1605 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 D 1502 |
| Chain | Residue |
| B | ARG1429 |
| D | ARG1429 |
| D | ARG1432 |
| D | HOH1612 |
| site_id | AC4 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 E 101 |
| site_id | AC5 |
| Number of Residues | 13 |
| Details | binding site for residue WCP F 101 |
| Chain | Residue |
| B | ALA1068 |
| B | GLY1072 |
| B | MET1075 |
| B | ASP1083 |
| B | MET1121 |
| D | ALA1068 |
| D | GLY1072 |
| D | MET1075 |
| D | ASP1083 |
| E | G10 |
| E | C11 |
| F | G10 |
| F | C11 |
| site_id | AC6 |
| Number of Residues | 5 |
| Details | binding site for residue SO4 F 102 |
| Chain | Residue |
| E | DT14 |
| E | A15 |
| F | G5 |
| F | DT6 |
| F | A7 |
Functional Information from PROSITE/UniProt
| site_id | PS00177 |
| Number of Residues | 9 |
| Details | TOPOISOMERASE_II DNA topoisomerase II signature. LVEGDSAGG |
| Chain | Residue | Details |
| B | LEU433-GLY441 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 228 |
| Details | Domain: {"description":"Toprim","evidences":[{"source":"HAMAP-Rule","id":"MF_01898","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 6 |
| Details | Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_01898","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 4 |
| Details | Site: {"description":"Interaction with DNA","evidences":[{"source":"HAMAP-Rule","id":"MF_01898","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | Active site: {"description":"O-(5'-phospho-DNA)-tyrosine intermediate","evidences":[{"source":"HAMAP-Rule","id":"MF_01897","evidenceCode":"ECO:0000255"}]} |
