5BQ2
Crystal structure of UDP-N-acetylglucosamine 1-carboxyvinyltransferase (UDP-N-acetylglucosamine enolpyruvyl transferase, EPT) from Pseudomonas aeruginosa
Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0003824 | molecular_function | catalytic activity |
A | 0005737 | cellular_component | cytoplasm |
A | 0008360 | biological_process | regulation of cell shape |
A | 0008760 | molecular_function | UDP-N-acetylglucosamine 1-carboxyvinyltransferase activity |
A | 0009252 | biological_process | peptidoglycan biosynthetic process |
A | 0016740 | molecular_function | transferase activity |
A | 0016765 | molecular_function | transferase activity, transferring alkyl or aryl (other than methyl) groups |
A | 0019277 | biological_process | UDP-N-acetylgalactosamine biosynthetic process |
A | 0051301 | biological_process | cell division |
A | 0071555 | biological_process | cell wall organization |
B | 0003824 | molecular_function | catalytic activity |
B | 0005737 | cellular_component | cytoplasm |
B | 0008360 | biological_process | regulation of cell shape |
B | 0008760 | molecular_function | UDP-N-acetylglucosamine 1-carboxyvinyltransferase activity |
B | 0009252 | biological_process | peptidoglycan biosynthetic process |
B | 0016740 | molecular_function | transferase activity |
B | 0016765 | molecular_function | transferase activity, transferring alkyl or aryl (other than methyl) groups |
B | 0019277 | biological_process | UDP-N-acetylgalactosamine biosynthetic process |
B | 0051301 | biological_process | cell division |
B | 0071555 | biological_process | cell wall organization |
C | 0003824 | molecular_function | catalytic activity |
C | 0005737 | cellular_component | cytoplasm |
C | 0008360 | biological_process | regulation of cell shape |
C | 0008760 | molecular_function | UDP-N-acetylglucosamine 1-carboxyvinyltransferase activity |
C | 0009252 | biological_process | peptidoglycan biosynthetic process |
C | 0016740 | molecular_function | transferase activity |
C | 0016765 | molecular_function | transferase activity, transferring alkyl or aryl (other than methyl) groups |
C | 0019277 | biological_process | UDP-N-acetylgalactosamine biosynthetic process |
C | 0051301 | biological_process | cell division |
C | 0071555 | biological_process | cell wall organization |
D | 0003824 | molecular_function | catalytic activity |
D | 0005737 | cellular_component | cytoplasm |
D | 0008360 | biological_process | regulation of cell shape |
D | 0008760 | molecular_function | UDP-N-acetylglucosamine 1-carboxyvinyltransferase activity |
D | 0009252 | biological_process | peptidoglycan biosynthetic process |
D | 0016740 | molecular_function | transferase activity |
D | 0016765 | molecular_function | transferase activity, transferring alkyl or aryl (other than methyl) groups |
D | 0019277 | biological_process | UDP-N-acetylgalactosamine biosynthetic process |
D | 0051301 | biological_process | cell division |
D | 0071555 | biological_process | cell wall organization |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 33 |
Details | binding site for residue EPU A 501 |
Chain | Residue |
A | LYS22 |
A | VAL164 |
A | SER165 |
A | VAL166 |
A | THR167 |
A | ASP308 |
A | VAL330 |
A | PHE331 |
A | LEU373 |
A | HOH631 |
A | HOH642 |
A | ASN23 |
A | HOH648 |
A | HOH657 |
A | HOH664 |
A | HOH668 |
A | HOH673 |
A | HOH677 |
A | HOH785 |
A | HOH801 |
A | HOH820 |
A | HOH834 |
A | SER121 |
A | HOH854 |
A | HOH857 |
A | HOH870 |
A | HOH893 |
A | ARG122 |
A | PRO123 |
A | VAL124 |
A | ASP125 |
A | LEU126 |
A | THR163 |
site_id | AC2 |
Number of Residues | 5 |
Details | binding site for residue MG A 502 |
Chain | Residue |
A | QPA117 |
A | HOH684 |
A | HOH698 |
A | HOH903 |
A | HOH938 |
site_id | AC3 |
Number of Residues | 30 |
Details | binding site for residue EPU B 501 |
Chain | Residue |
B | LYS22 |
B | ASN23 |
B | SER121 |
B | ARG122 |
B | PRO123 |
B | VAL124 |
B | ASP125 |
B | LEU126 |
B | THR163 |
B | VAL164 |
B | SER165 |
B | VAL166 |
B | THR167 |
B | ASP308 |
B | VAL330 |
B | PHE331 |
B | LEU373 |
B | HOH641 |
B | HOH665 |
B | HOH671 |
B | HOH684 |
B | HOH687 |
B | HOH721 |
B | HOH742 |
B | HOH802 |
B | HOH812 |
B | HOH836 |
B | HOH874 |
B | HOH894 |
B | HOH917 |
site_id | AC4 |
Number of Residues | 5 |
Details | binding site for residue MG B 502 |
Chain | Residue |
B | QPA117 |
B | HOH639 |
B | HOH680 |
B | HOH868 |
B | HOH925 |
site_id | AC5 |
Number of Residues | 32 |
Details | binding site for residue EPU C 501 |
Chain | Residue |
C | HOH821 |
C | HOH839 |
C | HOH844 |
C | HOH860 |
C | HOH928 |
C | HOH931 |
C | LYS22 |
C | ASN23 |
C | SER121 |
C | ARG122 |
C | PRO123 |
C | VAL124 |
C | ASP125 |
C | LEU126 |
C | THR163 |
C | VAL164 |
C | SER165 |
C | VAL166 |
C | THR167 |
C | ASP308 |
C | VAL330 |
C | PHE331 |
C | LEU373 |
C | HOH636 |
C | HOH673 |
C | HOH680 |
C | HOH682 |
C | HOH696 |
C | HOH704 |
C | HOH715 |
C | HOH773 |
C | HOH818 |
site_id | AC6 |
Number of Residues | 5 |
Details | binding site for residue MG C 502 |
Chain | Residue |
C | QPA117 |
C | HOH675 |
C | HOH732 |
C | HOH900 |
C | HOH918 |
site_id | AC7 |
Number of Residues | 6 |
Details | binding site for residue MG C 503 |
Chain | Residue |
A | HOH876 |
B | HOH688 |
B | HOH736 |
C | ASN353 |
C | HOH764 |
C | HOH921 |
site_id | AC8 |
Number of Residues | 33 |
Details | binding site for residue EPU D 501 |
Chain | Residue |
D | LYS22 |
D | ASN23 |
D | ALA94 |
D | SER121 |
D | ARG122 |
D | PRO123 |
D | VAL124 |
D | ASP125 |
D | LEU126 |
D | THR163 |
D | VAL164 |
D | SER165 |
D | VAL166 |
D | THR167 |
D | ASP308 |
D | VAL330 |
D | PHE331 |
D | LEU373 |
D | HOH656 |
D | HOH673 |
D | HOH674 |
D | HOH681 |
D | HOH683 |
D | HOH687 |
D | HOH693 |
D | HOH700 |
D | HOH706 |
D | HOH751 |
D | HOH796 |
D | HOH864 |
D | HOH876 |
D | HOH893 |
D | HOH952 |
site_id | AC9 |
Number of Residues | 5 |
Details | binding site for residue MG D 502 |
Chain | Residue |
D | QPA117 |
D | HOH646 |
D | HOH670 |
D | HOH902 |
D | HOH933 |
site_id | AD1 |
Number of Residues | 6 |
Details | binding site for residue MG D 503 |
Chain | Residue |
A | HOH622 |
A | HOH670 |
B | HOH851 |
D | ASN353 |
D | HOH806 |
D | HOH926 |
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 4 |
Details | ACT_SITE: Proton donor => ECO:0000255|HAMAP-Rule:MF_00111 |
Chain | Residue | Details |
A | QPA117 | |
B | QPA117 | |
C | QPA117 | |
D | QPA117 |
site_id | SWS_FT_FI2 |
Number of Residues | 20 |
Details | BINDING: BINDING => ECO:0007744|PDB:5BQ2 |
Chain | Residue | Details |
A | LYS22 | |
B | VAL330 | |
C | LYS22 | |
C | ARG122 | |
C | SER165 | |
C | ASP308 | |
C | VAL330 | |
D | LYS22 | |
D | ARG122 | |
D | SER165 | |
D | ASP308 | |
A | ARG122 | |
D | VAL330 | |
A | SER165 | |
A | ASP308 | |
A | VAL330 | |
B | LYS22 | |
B | ARG122 | |
B | SER165 | |
B | ASP308 |
site_id | SWS_FT_FI3 |
Number of Residues | 4 |
Details | BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_00111 |
Chain | Residue | Details |
A | ARG93 | |
B | ARG93 | |
C | ARG93 | |
D | ARG93 |
site_id | SWS_FT_FI4 |
Number of Residues | 4 |
Details | MOD_RES: 2-(S-cysteinyl)pyruvic acid O-phosphothioketal => ECO:0000255|HAMAP-Rule:MF_00111 |
Chain | Residue | Details |
A | QPA117 | |
B | QPA117 | |
C | QPA117 | |
D | QPA117 |