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5BPE

Crystal structure of EV71 3Cpro in complex with a potent and selective Inhibitor

Functional Information from GO Data
ChainGOidnamespacecontents
A0003723molecular_functionRNA binding
A0004197molecular_functioncysteine-type endopeptidase activity
A0006508biological_processproteolysis
A0008233molecular_functionpeptidase activity
A0008234molecular_functioncysteine-type peptidase activity
A0016787molecular_functionhydrolase activity
A0019028cellular_componentviral capsid
A0019062biological_processvirion attachment to host cell
A0030430cellular_componenthost cell cytoplasm
A0039618cellular_componentT=pseudo3 icosahedral viral capsid
A0044423cellular_componentvirion component
A0046718biological_processsymbiont entry into host cell
Functional Information from PDB Data
site_idAC1
Number of Residues17
Detailsbinding site for residue E22 A 201
ChainResidue
AHIS40
AGLY145
AGLN146
ACYS147
AHIS161
AILE162
AGLY163
AGLY164
AHOH301
AGLU71
AASN126
ALEU127
ASER128
ALYS130
ATHR142
ALYS143
AALA144

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PDB entries from 2025-06-18

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