5BPE
Crystal structure of EV71 3Cpro in complex with a potent and selective Inhibitor
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003723 | molecular_function | RNA binding |
| A | 0004197 | molecular_function | cysteine-type endopeptidase activity |
| A | 0006508 | biological_process | proteolysis |
| A | 0008233 | molecular_function | peptidase activity |
| A | 0008234 | molecular_function | cysteine-type peptidase activity |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0019028 | cellular_component | viral capsid |
| A | 0019062 | biological_process | virion attachment to host cell |
| A | 0030430 | cellular_component | host cell cytoplasm |
| A | 0039618 | cellular_component | T=pseudo3 icosahedral viral capsid |
| A | 0044423 | cellular_component | virion component |
| A | 0046718 | biological_process | symbiont entry into host cell |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 17 |
| Details | binding site for residue E22 A 201 |
| Chain | Residue |
| A | HIS40 |
| A | GLY145 |
| A | GLN146 |
| A | CYS147 |
| A | HIS161 |
| A | ILE162 |
| A | GLY163 |
| A | GLY164 |
| A | HOH301 |
| A | GLU71 |
| A | ASN126 |
| A | LEU127 |
| A | SER128 |
| A | LYS130 |
| A | THR142 |
| A | LYS143 |
| A | ALA144 |






