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5BP4

Modifying region (DH-ER-KR) of a mycocerosic acid synthase-like (MAS-like) PKS

This is a non-PDB format compatible entry.
Functional Information from GO Data
ChainGOidnamespacecontents
A0016491molecular_functionoxidoreductase activity
B0016491molecular_functionoxidoreductase activity
C0016491molecular_functionoxidoreductase activity
D0016491molecular_functionoxidoreductase activity
E0016491molecular_functionoxidoreductase activity
F0016491molecular_functionoxidoreductase activity
G0016491molecular_functionoxidoreductase activity
H0016491molecular_functionoxidoreductase activity
I0016491molecular_functionoxidoreductase activity
J0016491molecular_functionoxidoreductase activity
K0016491molecular_functionoxidoreductase activity
L0016491molecular_functionoxidoreductase activity
M0016491molecular_functionoxidoreductase activity
N0016491molecular_functionoxidoreductase activity
O0016491molecular_functionoxidoreductase activity
P0016491molecular_functionoxidoreductase activity
Q0016491molecular_functionoxidoreductase activity
R0016491molecular_functionoxidoreductase activity
Functional Information from PDB Data
site_idAC1
Number of Residues19
Detailsbinding site for residue NAP A 3001
ChainResidue
APHE1460
AARG1595
ASER1610
AARG1611
AILE1656
AVAL1681
AASP1682
ALEU1683
AMET1730
AGLY1731
AHIS1735
AARG1469
ATHR1545
ASER1566
AGLY1569
AGLY1570
AVAL1571
AALA1590
AGLY1591

site_idAC2
Number of Residues12
Detailsbinding site for residue NAP A 3002
ChainResidue
AGLY1771
AGLY1774
AGLY1775
ALEU1776
ASER1796
AARG1797
ASER1798
AASP1824
AILE1825
AALA1853
AVAL1854
APRO1874

site_idAC3
Number of Residues18
Detailsbinding site for residue NAP B 3001
ChainResidue
BPHE1460
BARG1469
BTHR1545
BSER1566
BGLY1569
BGLY1570
BVAL1571
BALA1590
BGLY1591
BARG1595
BSER1610
BARG1611
BILE1656
BVAL1681
BASP1682
BLEU1683
BGLY1731
BHIS1735

site_idAC4
Number of Residues12
Detailsbinding site for residue NAP B 3002
ChainResidue
BGLY1771
BGLY1774
BGLY1775
BSER1796
BARG1797
BSER1798
BGLY1823
BASP1824
BILE1825
BALA1852
BALA1853
BVAL1854

site_idAC5
Number of Residues19
Detailsbinding site for residue NAP C 3001
ChainResidue
CPHE1460
CARG1469
CTHR1545
CSER1566
CGLY1569
CGLY1570
CVAL1571
CALA1590
CGLY1591
CARG1595
CSER1610
CARG1611
CILE1656
CLYS1658
CVAL1681
CLEU1683
CMET1730
CGLY1731
CHIS1735

site_idAC6
Number of Residues12
Detailsbinding site for residue NAP C 3002
ChainResidue
CGLY1771
CGLY1774
CGLY1775
CSER1796
CARG1797
CSER1798
CGLY1823
CASP1824
CILE1825
CALA1852
CALA1853
CVAL1854

site_idAC7
Number of Residues19
Detailsbinding site for residue NAP D 3001
ChainResidue
DALA1590
DGLY1591
DARG1595
DSER1610
DARG1611
DILE1656
DLYS1658
DVAL1681
DASP1682
DLEU1683
DGLY1731
DHIS1735
DPHE1460
DARG1469
DTHR1545
DSER1566
DGLY1569
DGLY1570
DVAL1571

site_idAC8
Number of Residues12
Detailsbinding site for residue NAP D 3002
ChainResidue
DGLY1771
DGLY1774
DGLY1775
DSER1796
DARG1797
DSER1798
DGLY1823
DASP1824
DILE1825
DALA1852
DALA1853
DVAL1854

site_idAC9
Number of Residues19
Detailsbinding site for residue NAP E 3001
ChainResidue
EPHE1460
ETHR1545
ESER1566
EGLY1569
EGLY1570
EVAL1571
EGLY1591
EARG1595
ESER1610
EARG1611
EILE1656
ELYS1658
EVAL1681
EASP1682
ELEU1683
EMET1730
EGLY1731
EALA1733
EHIS1735

site_idAD1
Number of Residues15
Detailsbinding site for residue NAP F 3001
ChainResidue
FASN1459
FPHE1460
FALA1461
FLEU1541
FSER1566
FGLY1569
FGLY1570
FVAL1571
FALA1590
FGLY1591
FARG1595
FSER1610
FARG1611
FGLY1731
FHIS1735

site_idAD2
Number of Residues12
Detailsbinding site for residue NAP F 3002
ChainResidue
FGLY1771
FGLY1774
FGLY1775
FSER1796
FARG1797
FSER1798
FGLY1823
FASP1824
FILE1825
FALA1852
FALA1853
FVAL1854

site_idAD3
Number of Residues17
Detailsbinding site for residue NAP G 3001
ChainResidue
GPHE1460
GARG1469
GTHR1545
GSER1566
GGLY1569
GGLY1570
GVAL1571
GALA1590
GGLY1591
GARG1595
GSER1610
GARG1611
GILE1656
GVAL1681
GLEU1683
GGLY1731
GHIS1735

site_idAD4
Number of Residues12
Detailsbinding site for residue NAP G 3002
ChainResidue
GGLY1771
GGLY1774
GGLY1775
GASN1795
GSER1796
GARG1797
GSER1798
GGLY1823
GASP1824
GILE1825
GALA1853
GVAL1854

site_idAD5
Number of Residues17
Detailsbinding site for residue NAP H 3001
ChainResidue
HPHE1460
HTHR1545
HSER1566
HGLY1569
HGLY1570
HVAL1571
HALA1590
HGLY1591
HARG1595
HSER1610
HARG1611
HILE1656
HVAL1681
HASP1682
HLEU1683
HGLY1731
HHIS1735

site_idAD6
Number of Residues13
Detailsbinding site for residue NAP H 3002
ChainResidue
HGLY1771
HGLY1774
HGLY1775
HSER1796
HARG1797
HSER1798
HGLY1823
HASP1824
HILE1825
HALA1852
HALA1853
HVAL1854
HPRO1874

site_idAD7
Number of Residues19
Detailsbinding site for residue NAP I 3001
ChainResidue
IPHE1460
IARG1469
ITHR1545
ISER1566
IGLY1569
IGLY1570
IVAL1571
IALA1590
IGLY1591
IARG1595
ISER1610
IARG1611
IILE1656
ILYS1658
IVAL1681
IASP1682
ILEU1683
IGLY1731
IHIS1735

site_idAD8
Number of Residues18
Detailsbinding site for residue NAP J 3001
ChainResidue
JPHE1460
JARG1469
JTHR1545
JSER1566
JGLY1569
JGLY1570
JVAL1571
JALA1590
JGLY1591
JARG1595
JSER1610
JARG1611
JILE1656
JVAL1681
JASP1682
JLEU1683
JGLY1731
JHIS1735

site_idAD9
Number of Residues10
Detailsbinding site for residue NAP J 3002
ChainResidue
JGLY1771
JGLY1774
JGLY1775
JSER1796
JARG1797
JSER1798
JASP1824
JILE1825
JALA1853
JVAL1854

site_idAE1
Number of Residues18
Detailsbinding site for residue NAP K 3001
ChainResidue
KPHE1460
KTHR1545
KSER1566
KGLY1569
KGLY1570
KVAL1571
KALA1590
KGLY1591
KARG1595
KSER1610
KARG1611
KSER1634
KILE1656
KLYS1658
KASP1682
KLEU1683
KGLY1731
KHIS1735

site_idAE2
Number of Residues13
Detailsbinding site for residue NAP K 3002
ChainResidue
KGLY1771
KGLY1774
KGLY1775
KASN1795
KSER1796
KARG1797
KSER1798
KGLY1823
KASP1824
KILE1825
KALA1852
KALA1853
KVAL1854

site_idAE3
Number of Residues18
Detailsbinding site for residue NAP L 3001
ChainResidue
LPHE1460
LARG1469
LTHR1545
LSER1566
LGLY1569
LVAL1571
LALA1590
LGLY1591
LARG1595
LSER1610
LARG1611
LILE1656
LLYS1658
LVAL1681
LASP1682
LLEU1683
LGLY1731
LHIS1735

site_idAE4
Number of Residues18
Detailsbinding site for residue NAP M 3001
ChainResidue
MPHE1460
MARG1469
MTHR1545
MSER1566
MGLY1569
MGLY1570
MVAL1571
MGLY1591
MARG1595
MSER1610
MARG1611
MILE1656
MVAL1681
MASP1682
MLEU1683
MMET1730
MGLY1731
MHIS1735

site_idAE5
Number of Residues10
Detailsbinding site for residue NAP M 3002
ChainResidue
MGLY1771
MGLY1774
MGLY1775
MSER1796
MARG1797
MSER1798
MASP1824
MILE1825
MALA1853
MVAL1854

site_idAE6
Number of Residues18
Detailsbinding site for residue NAP N 3001
ChainResidue
NPHE1460
NARG1469
NSER1566
NGLY1569
NGLY1570
NVAL1571
NALA1590
NGLY1591
NARG1595
NSER1610
NARG1611
NILE1656
NVAL1681
NASP1682
NLEU1683
NMET1730
NGLY1731
NHIS1735

site_idAE7
Number of Residues11
Detailsbinding site for residue NAP N 3002
ChainResidue
NGLY1771
NGLY1774
NASN1795
NSER1796
NARG1797
NSER1798
NGLY1823
NASP1824
NILE1825
NALA1853
NVAL1854

site_idAE8
Number of Residues17
Detailsbinding site for residue NAP O 3001
ChainResidue
OPHE1460
OTHR1545
OSER1566
OGLY1569
OGLY1570
OVAL1571
OGLY1591
OARG1595
OSER1610
OARG1611
OILE1656
OLYS1658
OVAL1681
OASP1682
OLEU1683
OGLY1731
OHIS1735

site_idAE9
Number of Residues18
Detailsbinding site for residue NAP P 3001
ChainResidue
PPHE1460
PARG1469
PTHR1545
PSER1566
PGLY1569
PGLY1570
PVAL1571
PALA1590
PGLY1591
PARG1595
PSER1610
PARG1611
PILE1656
PVAL1681
PASP1682
PLEU1683
PGLY1731
PHIS1735

site_idAF1
Number of Residues12
Detailsbinding site for residue NAP P 3002
ChainResidue
PGLY1771
PGLY1774
PGLY1775
PSER1796
PARG1797
PSER1798
PGLY1823
PASP1824
PILE1825
PALA1852
PALA1853
PVAL1854

site_idAF2
Number of Residues16
Detailsbinding site for residue NAP Q 3001
ChainResidue
QPHE1460
QSER1566
QGLY1569
QGLY1570
QVAL1571
QALA1590
QGLY1591
QARG1595
QSER1610
QARG1611
QSER1634
QILE1656
QVAL1681
QMET1730
QHIS1735
QGLY1737

site_idAF3
Number of Residues20
Detailsbinding site for residue NAP R 3001
ChainResidue
RPHE1460
RARG1469
RTHR1545
RSER1566
RGLY1569
RGLY1570
RVAL1571
RALA1590
RGLY1591
RARG1595
RSER1610
RARG1611
RILE1656
RLYS1658
RVAL1681
RASP1682
RLEU1683
RMET1730
RGLY1731
RHIS1735

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues18
DetailsACT_SITE: Proton acceptor; for dehydratase activity => ECO:0000255|PROSITE-ProRule:PRU01363
ChainResidueDetails
AHIS934
JHIS934
KHIS934
LHIS934
MHIS934
NHIS934
OHIS934
PHIS934
QHIS934
RHIS934
BHIS934
CHIS934
DHIS934
EHIS934
FHIS934
GHIS934
HHIS934
IHIS934

site_idSWS_FT_FI2
Number of Residues18
DetailsACT_SITE: Proton donor; for dehydratase activity => ECO:0000255|PROSITE-ProRule:PRU01363
ChainResidueDetails
AASP1100
JASP1100
KASP1100
LASP1100
MASP1100
NASP1100
OASP1100
PASP1100
QASP1100
RASP1100
BASP1100
CASP1100
DASP1100
EASP1100
FASP1100
GASP1100
HASP1100
IASP1100

site_idSWS_FT_FI3
Number of Residues72
DetailsBINDING: BINDING => ECO:0000250|UniProtKB:Q03131
ChainResidueDetails
ALEU1773
CSER1796
CASP1824
CPHE1902
DLEU1773
DSER1796
DASP1824
DPHE1902
ELEU1773
ESER1796
EASP1824
ASER1796
EPHE1902
FLEU1773
FSER1796
FASP1824
FPHE1902
GLEU1773
GSER1796
GASP1824
GPHE1902
HLEU1773
AASP1824
HSER1796
HASP1824
HPHE1902
ILEU1773
ISER1796
IASP1824
IPHE1902
JLEU1773
JSER1796
JASP1824
APHE1902
JPHE1902
KLEU1773
KSER1796
KASP1824
KPHE1902
LLEU1773
LSER1796
LASP1824
LPHE1902
MLEU1773
BLEU1773
MSER1796
MASP1824
MPHE1902
NLEU1773
NSER1796
NASP1824
NPHE1902
OLEU1773
OSER1796
OASP1824
BSER1796
OPHE1902
PLEU1773
PSER1796
PASP1824
PPHE1902
QLEU1773
QSER1796
QASP1824
QPHE1902
RLEU1773
BASP1824
RSER1796
RASP1824
RPHE1902
BPHE1902
CLEU1773

227344

PDB entries from 2024-11-13

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