Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 3 |
| Details | binding site for residue MG A 1201 |
| Chain | Residue |
| A | THR925 |
| A | GLU926 |
| A | ASP978 |
| site_id | AC2 |
| Number of Residues | 3 |
| Details | binding site for residue EDO A 1202 |
| Chain | Residue |
| A | LYS1146 |
| A | ASP1148 |
| A | GLY1151 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | binding site for residue EDO A 1203 |
| Chain | Residue |
| A | HOH1407 |
| A | HOH1440 |
| A | LEU1141 |
| A | ARG1143 |
| A | ASP1155 |
| site_id | AC4 |
| Number of Residues | 2 |
| Details | binding site for residue EDO A 1204 |
| Chain | Residue |
| A | ASP933 |
| A | ALA1058 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | binding site for residue EDO A 1205 |
| Chain | Residue |
| A | PHE970 |
| A | HIS971 |
| A | GLN1008 |
| A | THR1011 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | binding site for residue EDO A 1206 |
| Chain | Residue |
| A | HIS966 |
| A | ASP967 |
| A | VAL1013 |
| A | ARG1015 |
| site_id | AC7 |
| Number of Residues | 5 |
| Details | binding site for residue EDO A 1207 |
| Chain | Residue |
| A | GLU995 |
| A | PHE996 |
| A | THR1011 |
| A | ALA1012 |
| A | VAL1013 |
| site_id | AC8 |
| Number of Residues | 6 |
| Details | binding site for residue EDO A 1208 |
| Chain | Residue |
| A | LEU975 |
| A | ASP977 |
| A | ALA979 |
| A | THR980 |
| A | HIS1001 |
| A | HOH1311 |
| site_id | AC9 |
| Number of Residues | 4 |
| Details | binding site for residue EDO A 1209 |
| Chain | Residue |
| A | THR1069 |
| A | GLU1072 |
| A | HOH1366 |
| C | GLN938 |
| site_id | AD1 |
| Number of Residues | 6 |
| Details | binding site for residue EDO A 1210 |
| Chain | Residue |
| A | GLN1113 |
| A | ALA1116 |
| A | SER1117 |
| A | EDO1213 |
| C | ALA1025 |
| C | HOH1358 |
| site_id | AD2 |
| Number of Residues | 4 |
| Details | binding site for residue EDO A 1211 |
| Chain | Residue |
| A | SER899 |
| A | HIS901 |
| A | HOH1321 |
| A | HOH1423 |
| site_id | AD3 |
| Number of Residues | 5 |
| Details | binding site for residue EDO A 1212 |
| Chain | Residue |
| A | HIS934 |
| A | HIS1055 |
| A | ASP1100 |
| A | PHE1103 |
| A | LEU1121 |
| site_id | AD4 |
| Number of Residues | 8 |
| Details | binding site for residue EDO A 1213 |
| Chain | Residue |
| A | LEU1044 |
| A | GLY1047 |
| A | PHE1048 |
| A | ILE1107 |
| A | GLN1113 |
| A | EDO1210 |
| A | HOH1391 |
| A | HOH1452 |
| site_id | AD5 |
| Number of Residues | 10 |
| Details | binding site for residue GOL A 1214 |
| Chain | Residue |
| A | HIS934 |
| A | VAL941 |
| A | LEU942 |
| A | PRO943 |
| A | GLY944 |
| A | PHE970 |
| A | PRO1122 |
| A | HOH1325 |
| A | HOH1350 |
| A | HOH1417 |
| site_id | AD6 |
| Number of Residues | 5 |
| Details | binding site for residue CL A 1215 |
| Chain | Residue |
| A | VAL900 |
| A | HIS901 |
| A | GLY905 |
| A | HOH1339 |
| A | HOH1430 |
| site_id | AD7 |
| Number of Residues | 3 |
| Details | binding site for residue EDO B 1201 |
| Chain | Residue |
| B | PHE970 |
| B | HIS971 |
| B | LEU1123 |
| site_id | AD8 |
| Number of Residues | 6 |
| Details | binding site for residue EDO B 1202 |
| Chain | Residue |
| B | PHE1103 |
| B | ILE1107 |
| B | LEU1120 |
| B | LEU1121 |
| B | HOH1305 |
| B | HOH1347 |
| site_id | AD9 |
| Number of Residues | 7 |
| Details | binding site for residue GOL B 1203 |
| Chain | Residue |
| B | HIS934 |
| B | LEU942 |
| B | PRO943 |
| B | GLY944 |
| B | LEU1121 |
| B | PRO1122 |
| B | HOH1305 |
| site_id | AE1 |
| Number of Residues | 4 |
| Details | binding site for residue EDO C 1201 |
| Chain | Residue |
| C | HIS966 |
| C | ASP967 |
| C | ARG1126 |
| C | ARG1127 |
| site_id | AE2 |
| Number of Residues | 5 |
| Details | binding site for residue EDO C 1202 |
| Chain | Residue |
| C | ALA1058 |
| C | PRO1082 |
| C | PRO1084 |
| C | LEU1085 |
| C | PG41212 |
| site_id | AE3 |
| Number of Residues | 7 |
| Details | binding site for residue EDO C 1203 |
| Chain | Residue |
| C | GLY1061 |
| C | SER1063 |
| C | ALA1078 |
| C | VAL1079 |
| C | ALA1080 |
| C | EDO1206 |
| C | HOH1367 |
| site_id | AE4 |
| Number of Residues | 2 |
| Details | binding site for residue EDO C 1204 |
| Chain | Residue |
| C | GLN912 |
| C | GLU916 |
| site_id | AE5 |
| Number of Residues | 6 |
| Details | binding site for residue EDO C 1205 |
| Chain | Residue |
| C | ASP933 |
| C | ARG935 |
| C | GLY1054 |
| C | HIS1055 |
| C | GLY1056 |
| C | HOH1435 |
| site_id | AE6 |
| Number of Residues | 4 |
| Details | binding site for residue EDO C 1206 |
| Chain | Residue |
| C | VAL1079 |
| C | ARG1138 |
| C | TYR1139 |
| C | EDO1203 |
| site_id | AE7 |
| Number of Residues | 7 |
| Details | binding site for residue EDO C 1207 |
| Chain | Residue |
| C | PRO914 |
| C | VAL988 |
| C | THR989 |
| C | ALA990 |
| C | PRO991 |
| C | EDO1208 |
| C | HOH1301 |
| site_id | AE8 |
| Number of Residues | 4 |
| Details | binding site for residue EDO C 1208 |
| Chain | Residue |
| C | PRO914 |
| C | GLU915 |
| C | EDO1207 |
| C | HOH1301 |
| site_id | AE9 |
| Number of Residues | 7 |
| Details | binding site for residue EDO C 1209 |
| Chain | Residue |
| C | PHE1103 |
| C | ILE1107 |
| C | LEU1120 |
| C | LEU1121 |
| C | PRO1122 |
| C | HOH1318 |
| C | HOH1366 |
| site_id | AF1 |
| Number of Residues | 9 |
| Details | binding site for residue GOL C 1210 |
| Chain | Residue |
| C | HIS934 |
| C | VAL941 |
| C | LEU942 |
| C | PRO943 |
| C | GLY944 |
| C | PHE970 |
| C | PRO1122 |
| C | HOH1341 |
| C | HOH1424 |
| site_id | AF2 |
| Number of Residues | 1 |
| Details | binding site for residue CL C 1211 |
| site_id | AF3 |
| Number of Residues | 7 |
| Details | binding site for residue PG4 C 1212 |
| Chain | Residue |
| C | GLY1083 |
| C | PRO1084 |
| C | EDO1202 |
| D | THR989 |
| D | ALA990 |
| D | PRO991 |
| D | EDO1208 |
| site_id | AF4 |
| Number of Residues | 6 |
| Details | binding site for residue MG D 1201 |
| Chain | Residue |
| C | HOH1457 |
| D | ASP972 |
| D | HOH1331 |
| D | HOH1350 |
| D | HOH1372 |
| D | HOH1454 |
| site_id | AF5 |
| Number of Residues | 4 |
| Details | binding site for residue EDO D 1202 |
| Chain | Residue |
| D | LYS969 |
| D | HIS971 |
| D | ARG1009 |
| D | THR1011 |
| site_id | AF6 |
| Number of Residues | 5 |
| Details | binding site for residue EDO D 1203 |
| Chain | Residue |
| D | TRP983 |
| D | SER985 |
| D | GLY997 |
| D | VAL998 |
| D | GLU999 |
| site_id | AF7 |
| Number of Residues | 2 |
| Details | binding site for residue EDO D 1204 |
| Chain | Residue |
| D | VAL1039 |
| D | HOH1338 |
| site_id | AF8 |
| Number of Residues | 5 |
| Details | binding site for residue EDO D 1205 |
| Chain | Residue |
| D | LEU1141 |
| D | ARG1143 |
| D | ASP1155 |
| D | GLU1157 |
| D | HOH1451 |
| site_id | AF9 |
| Number of Residues | 4 |
| Details | binding site for residue EDO D 1206 |
| Chain | Residue |
| D | ASP967 |
| D | LYS969 |
| D | THR1011 |
| D | ALA1012 |
| site_id | AG1 |
| Number of Residues | 5 |
| Details | binding site for residue EDO D 1207 |
| Chain | Residue |
| D | LEU1032 |
| D | ALA1033 |
| D | HIS1035 |
| D | PRO1036 |
| D | TYR1066 |
| site_id | AG2 |
| Number of Residues | 6 |
| Details | binding site for residue EDO D 1208 |
| Chain | Residue |
| C | PG41212 |
| D | PRO914 |
| D | VAL988 |
| D | THR989 |
| D | ALA990 |
| D | PRO991 |
| site_id | AG3 |
| Number of Residues | 8 |
| Details | binding site for residue EDO D 1209 |
| Chain | Residue |
| D | PHE970 |
| D | HIS971 |
| D | MET973 |
| D | LEU1123 |
| D | GLY1177 |
| D | GOL1212 |
| D | HOH1366 |
| D | HOH1432 |
| site_id | AG4 |
| Number of Residues | 5 |
| Details | binding site for residue EDO D 1210 |
| Chain | Residue |
| D | ILE1107 |
| D | LEU1120 |
| D | LEU1121 |
| D | PRO1122 |
| D | HOH1314 |
| site_id | AG5 |
| Number of Residues | 4 |
| Details | binding site for residue GOL D 1211 |
| Chain | Residue |
| D | HIS966 |
| D | ASP967 |
| D | ARG1126 |
| D | ARG1127 |
| site_id | AG6 |
| Number of Residues | 8 |
| Details | binding site for residue GOL D 1212 |
| Chain | Residue |
| D | HIS934 |
| D | LEU942 |
| D | PRO943 |
| D | GLY944 |
| D | LEU1121 |
| D | PRO1122 |
| D | EDO1209 |
| D | HOH1314 |
| site_id | AG7 |
| Number of Residues | 2 |
| Details | binding site for residue CL D 1213 |
| Chain | Residue |
| D | HIS966 |
| D | ARG1015 |
