Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005509 | molecular_function | calcium ion binding |
| A | 0007154 | biological_process | cell communication |
| A | 0016020 | cellular_component | membrane |
| B | 0005509 | molecular_function | calcium ion binding |
| B | 0007154 | biological_process | cell communication |
| B | 0016020 | cellular_component | membrane |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 2 |
| Details | binding site for residue GOL A 401 |
| Chain | Residue |
| A | GLY309 |
| A | THR311 |
| site_id | AC2 |
| Number of Residues | 3 |
| Details | binding site for residue GOL B 401 |
| Chain | Residue |
| B | GLY309 |
| B | THR311 |
| B | SER323 |
Functional Information from PROSITE/UniProt
| site_id | PS00022 |
| Number of Residues | 12 |
| Details | EGF_1 EGF-like domain signature 1. CrCqyGwqGLyC |
| Chain | Residue | Details |
| A | CYS251-CYS262 | |
| A | CYS282-CYS293 | |
| A | CYS322-CYS333 | |
| site_id | PS00290 |
| Number of Residues | 7 |
| Details | IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YICNVNH |
| Chain | Residue | Details |
| H | TYR197-HIS203 | |
| L | TYR192-HIS198 | |
| site_id | PS01186 |
| Number of Residues | 15 |
| Details | EGF_2 EGF-like domain signature 2. CrCqyGWqglycdk.C |
| Chain | Residue | Details |
| A | CYS251-CYS265 | |
| A | CYS322-CYS333 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 66 |
| Details | Domain: {"description":"EGF-like 1","evidences":[{"source":"PROSITE-ProRule","id":"PRU00076","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 60 |
| Details | Domain: {"description":"EGF-like 2; atypical","evidences":[{"source":"PROSITE-ProRule","id":"PRU00076","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 76 |
| Details | Domain: {"description":"EGF-like 3","evidences":[{"source":"PROSITE-ProRule","id":"PRU00076","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI4 |
| Number of Residues | 16 |
| Details | Region: {"description":"Important for interaction with NOTCH1","evidences":[{"source":"PubMed","id":"18660822","evidenceCode":"ECO:0000269"}]} |
| site_id | SWS_FT_FI5 |
| Number of Residues | 2 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"evidenceCode":"ECO:0000255"}]} |
