5B74
Crystal structure of conjoined Pyrococcus furiosus L-asparaginase with peptide
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 10 |
| Details | binding site for residue FLC A 201 |
| Chain | Residue |
| A | GLY10 |
| B | HOH502 |
| A | THR11 |
| A | ASP51 |
| A | SER52 |
| A | THR53 |
| A | GLY82 |
| A | THR83 |
| A | ASP84 |
| A | SER109 |
| site_id | AC2 |
| Number of Residues | 3 |
| Details | binding site for residue CL A 202 |
| Chain | Residue |
| A | VAL71 |
| A | TYR74 |
| A | ILE102 |
| site_id | AC3 |
| Number of Residues | 1 |
| Details | binding site for residue CL B 401 |
| Chain | Residue |
| B | ASP214 |
Functional Information from PROSITE/UniProt
| site_id | PS00917 |
| Number of Residues | 11 |
| Details | ASN_GLN_ASE_2 Asparaginase / glutaminase active site signature 2. GiIvtHGTDTL |
| Chain | Residue | Details |
| A | GLY76-LEU86 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 3 |
| Details | Region: {"description":"Important for activity at high temperatures","evidences":[{"source":"PubMed","id":"33303914","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | Active site: {"description":"Nucleophile; O-isoaspartyl threonine intermediate","evidences":[{"source":"PubMed","id":"25478837","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 4 |
| Details | Active site: {"description":"Charge relay system","evidences":[{"source":"PubMed","id":"25478837","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 5 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"25478837","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4NJE","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5B5U","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
