5B5R

Crystal structure of GSDMA3

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0001786	molecular_function	phosphatidylserine binding
A	0001942	biological_process	hair follicle development
A	0001949	biological_process	sebaceous gland cell differentiation
A	0005546	molecular_function	phosphatidylinositol-4,5-bisphosphate binding
A	0005634	cellular_component	nucleus
A	0005829	cellular_component	cytosol
A	0005886	cellular_component	plasma membrane
A	0012501	biological_process	programmed cell death
A	0016020	cellular_component	membrane
A	0022829	molecular_function	wide pore channel activity
A	0030879	biological_process	mammary gland development
A	0031069	biological_process	hair follicle morphogenesis
A	0031966	cellular_component	mitochondrial membrane
A	0032731	biological_process	positive regulation of interleukin-1 beta production
A	0035019	biological_process	somatic stem cell population maintenance
A	0036331	biological_process	avascular cornea development in camera-type eye
A	0042633	biological_process	hair cycle
A	0042742	biological_process	defense response to bacterium
A	0043065	biological_process	positive regulation of apoptotic process
A	0043588	biological_process	skin development
A	0048471	cellular_component	perinuclear region of cytoplasm
A	0051886	biological_process	negative regulation of timing of anagen
A	0055085	biological_process	transmembrane transport
A	0070269	biological_process	pyroptotic inflammatory response
A	0070273	molecular_function	phosphatidylinositol-4-phosphate binding
A	0090090	biological_process	negative regulation of canonical Wnt signaling pathway
A	2001238	biological_process	positive regulation of extrinsic apoptotic signaling pathway

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	35
Details	Transmembrane: {"description":"Beta stranded","evidences":[{"source":"PubMed","id":"29695864","evidenceCode":"ECO:0000305"},{"source":"PDB","id":"6CB8","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	4
Details	Binding site: {"evidences":[{"source":"PubMed","id":"29695864","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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