Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004114 | molecular_function | 3',5'-cyclic-nucleotide phosphodiesterase activity |
| A | 0007165 | biological_process | signal transduction |
| A | 0008081 | molecular_function | phosphoric diester hydrolase activity |
| B | 0004114 | molecular_function | 3',5'-cyclic-nucleotide phosphodiesterase activity |
| B | 0007165 | biological_process | signal transduction |
| B | 0008081 | molecular_function | phosphoric diester hydrolase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | binding site for residue MG A 1001 |
| Chain | Residue |
| A | ASP554 |
| A | HOH1102 |
| A | HOH1103 |
| A | HOH1112 |
| A | HOH1127 |
| A | HOH1137 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | binding site for residue ZN A 1002 |
| Chain | Residue |
| A | ASP664 |
| A | HOH1117 |
| A | HOH1137 |
| A | HIS519 |
| A | HIS553 |
| A | ASP554 |
| site_id | AC3 |
| Number of Residues | 13 |
| Details | binding site for residue 6DT A 1003 |
| Chain | Residue |
| A | TYR514 |
| A | LEU665 |
| A | VAL668 |
| A | ILE682 |
| A | TYR683 |
| A | PHE686 |
| A | PRO702 |
| A | MET703 |
| A | GLU711 |
| A | GLY715 |
| A | GLN716 |
| A | PHE719 |
| A | HOH1146 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | binding site for residue MG B 1001 |
| Chain | Residue |
| B | ASP554 |
| B | HOH1102 |
| B | HOH1106 |
| B | HOH1117 |
| B | HOH1136 |
| B | HOH1141 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | binding site for residue ZN B 1002 |
| Chain | Residue |
| B | HIS519 |
| B | HIS553 |
| B | ASP554 |
| B | ASP664 |
| B | HOH1136 |
| site_id | AC6 |
| Number of Residues | 11 |
| Details | binding site for residue 6DT B 1003 |
| Chain | Residue |
| B | TYR514 |
| B | ILE682 |
| B | TYR683 |
| B | PHE686 |
| B | PRO702 |
| B | MET703 |
| B | LYS708 |
| B | GLU711 |
| B | GLY715 |
| B | GLN716 |
| B | PHE719 |
Functional Information from PROSITE/UniProt
| site_id | PS00126 |
| Number of Residues | 12 |
| Details | PDEASE_I_1 3'5'-cyclic nucleotide phosphodiesterase domain signature. HDLdHrGfsNsY |
| Chain | Residue | Details |
| A | HIS553-TYR564 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Proton donor","evidences":[{"source":"UniProtKB","id":"O76083","evidenceCode":"ECO:0000250"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 12 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"17389385","evidenceCode":"ECO:0000269"}]} |
