5B4F

Sulfur Transferase TtuA in complex with iron sulfur cluster

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000049	molecular_function	tRNA binding
A	0002098	biological_process	tRNA wobble uridine modification
A	0002143	biological_process	tRNA wobble position uridine thiolation
A	0002144	cellular_component	cytosolic tRNA wobble base thiouridylase complex
A	0005524	molecular_function	ATP binding
A	0008033	biological_process	tRNA processing
A	0016740	molecular_function	transferase activity
A	0034227	biological_process	tRNA thio-modification
A	0046872	molecular_function	metal ion binding
A	0051539	molecular_function	4 iron, 4 sulfur cluster binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	binding site for residue SO4 A 401

Chain	Residue
A	SER55
A	GLY57
A	LYS58
A	ASP59
A	SER60

---

site_id	AC2
Number of Residues	4
Details	binding site for residue SO4 A 402

Chain	Residue
A	LYS9
A	ARG297
A	LYS300
A	ARG312

---

site_id	AC3
Number of Residues	5
Details	binding site for residue SO4 A 403

Chain	Residue
A	VAL2
A	ALA10
A	ARG297
A	LYS301
A	SO4404

---

site_id	AC4
Number of Residues	4
Details	binding site for residue SO4 A 404

Chain	Residue
A	VAL2
A	ARG298
A	LYS301
A	SO4403

---

site_id	AC5
Number of Residues	6
Details	binding site for residue SO4 A 405

Chain	Residue
A	GLU13
A	ARG15
A	SER16
A	SER202
A	GLU205
A	HOH501

---

site_id	AC6
Number of Residues	4
Details	binding site for residue SO4 A 406

Chain	Residue
A	THR281
A	THR282
A	CYS286
A	ALA287

---

site_id	AC7
Number of Residues	4
Details	binding site for residue ZN A 407

Chain	Residue
A	CYS3
A	CYS6
A	CYS22
A	HIS25

---

site_id	AC8
Number of Residues	4
Details	binding site for residue ZN A 408

Chain	Residue
A	CYS274
A	CYS277
A	CYS286
A	CYS289

---

site_id	AC9
Number of Residues	5
Details	binding site for residue SF4 A 409

Chain	Residue
A	CYS130
A	CYS133
A	LYS137
A	CYS222
A	ASN224

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	8
Details	BINDING: BINDING => ECO:0000269|PubMed:28439027, ECO:0007744|PDB:5B4E, ECO:0007744|PDB:5B4F, ECO:0007744|PDB:5GHA

Chain	Residue	Details
A	CYS3
A	CYS6
A	CYS22
A	HIS25
A	CYS274
A	CYS277
A	CYS286
A	CYS289

---

site_id	SWS_FT_FI2
Number of Residues	5
Details	BINDING: BINDING => ECO:0000269|PubMed:28439027, ECO:0007744|PDB:5B4E

Chain	Residue	Details
A	ALA53
A	ASP59
A	ILE79
A	GLY156
A	ASP161

---

site_id	SWS_FT_FI3
Number of Residues	3
Details	BINDING: BINDING => ECO:0000269|PubMed:28439027, ECO:0007744|PDB:5B4E, ECO:0007744|PDB:5B4F

Chain	Residue	Details
A	CYS130
A	CYS133
A	CYS222

---

site_id	SWS_FT_FI4
Number of Residues	4
Details	CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in TtuB) => ECO:0000269|PubMed:22467871

Chain	Residue	Details
A	LYS137
A	LYS226
A	LYS229

---