5B47
2-Oxoacid:Ferredoxin Oxidoreductase 2 from Sulfolobus tokodai - pyruvate complex
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0006086 | biological_process | acetyl-CoA biosynthetic process from pyruvate |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0016903 | molecular_function | oxidoreductase activity, acting on the aldehyde or oxo group of donors |
| A | 0018491 | molecular_function | 2-oxobutyrate synthase activity |
| A | 0019164 | molecular_function | pyruvate synthase activity |
| A | 0047553 | molecular_function | 2-oxoglutarate synthase activity |
| B | 0000287 | molecular_function | magnesium ion binding |
| B | 0003824 | molecular_function | catalytic activity |
| B | 0006086 | biological_process | acetyl-CoA biosynthetic process from pyruvate |
| B | 0016491 | molecular_function | oxidoreductase activity |
| B | 0018491 | molecular_function | 2-oxobutyrate synthase activity |
| B | 0019164 | molecular_function | pyruvate synthase activity |
| B | 0030976 | molecular_function | thiamine pyrophosphate binding |
| B | 0046872 | molecular_function | metal ion binding |
| B | 0047553 | molecular_function | 2-oxoglutarate synthase activity |
| B | 0051539 | molecular_function | 4 iron, 4 sulfur cluster binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | binding site for residue PYR A 701 |
| Chain | Residue |
| A | SER42 |
| A | THR257 |
| A | ARG344 |
| A | PRO352 |
| B | ILE44 |
| B | TPP402 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | binding site for residue SF4 B 401 |
| Chain | Residue |
| B | CYS46 |
| B | CYS197 |
| A | ILE44 |
| B | CYS12 |
| B | CYS15 |
| site_id | AC3 |
| Number of Residues | 22 |
| Details | binding site for residue TPP B 402 |
| Chain | Residue |
| A | TYR254 |
| A | PRO255 |
| A | ILE256 |
| A | GLU294 |
| A | PRO318 |
| A | LEU322 |
| A | GLU325 |
| A | PYR701 |
| B | ILE44 |
| B | GLY45 |
| B | CYS46 |
| B | SER47 |
| B | HIS65 |
| B | ASP90 |
| B | GLY91 |
| B | ASP92 |
| B | ASN118 |
| B | VAL120 |
| B | TYR121 |
| B | GLY122 |
| B | LEU123 |
| B | MG403 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | binding site for residue MG B 403 |
| Chain | Residue |
| B | GLY89 |
| B | ASP90 |
| B | HIS116 |
| B | ASN118 |
| B | VAL120 |
| B | TPP402 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 8 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:27619895, ECO:0007744|PDB:5B46, ECO:0007744|PDB:5B47 |
| Chain | Residue | Details |
| B | CYS12 | |
| B | CYS15 | |
| B | ILE44 | |
| B | CYS46 | |
| B | ASP90 | |
| B | ASN118 | |
| B | VAL120 | |
| B | CYS197 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | BINDING: BINDING => ECO:0000305|PubMed:27619895 |
| Chain | Residue | Details |
| B | HIS65 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:27619895, ECO:0007744|PDB:5B46 |
| Chain | Residue | Details |
| B | GLY91 | |
| B | GLY122 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | SITE: Plays an important role in the binding of CoA => ECO:0000250|UniProtKB:Q96Y68 |
| Chain | Residue | Details |
| B | LYS125 |
