5B42

Crystal structure of the C-terminal endonuclease domain of Aquifex aeolicus MutL.

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005524	molecular_function	ATP binding
A	0006298	biological_process	mismatch repair
A	0016887	molecular_function	ATP hydrolysis activity
A	0032300	cellular_component	mismatch repair complex
A	0140664	molecular_function	ATP-dependent DNA damage sensor activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	7
Details	binding site for residue CD A 201

Chain	Residue
A	HIS30
A	GLU34
A	CYS48
A	CD205
A	HOH369
A	HOH373
A	HOH381

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site_id	AC2
Number of Residues	5
Details	binding site for residue CD A 202

Chain	Residue
A	HIS81
A	HOH345
A	HOH373
A	GLU34
A	CYS79

---

site_id	AC3
Number of Residues	4
Details	binding site for residue CD A 203

Chain	Residue
A	GLU61
A	TYR102
A	HOH376
A	HOH380

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site_id	AC4
Number of Residues	3
Details	binding site for residue CD A 204

Chain	Residue
A	ASP43
A	HOH374
A	HOH383

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site_id	AC5
Number of Residues	6
Details	binding site for residue CD A 205

Chain	Residue
A	CYS48
A	CD201
A	HOH301
A	HOH370
A	HOH381
A	HOH394

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site_id	AC6
Number of Residues	9
Details	binding site for residue PEG A 206

Chain	Residue
A	LYS2
A	TYR5
A	ASP20
A	TYR25
A	TRP70
A	PEG207
A	HOH303
A	HOH319
A	HOH344

---

site_id	AC7
Number of Residues	7
Details	binding site for residue PEG A 207

Chain	Residue
A	TYR25
A	TRP70
A	ARG71
A	TYR86
A	PEG206
A	HOH319
A	HOH326

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site_id	AC8
Number of Residues	5
Details	binding site for residue CD A 208

Chain	Residue
A	GLU93
A	GLU96
A	HOH307
A	HOH352
A	HOH371

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