5B1I
Crystal structure of K42A mutant of cystathionine beta-synthase from Lactobacillus plantarum in a complex with L-methionine
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004124 | molecular_function | cysteine synthase activity |
| A | 0008652 | biological_process | amino acid biosynthetic process |
| A | 0016740 | molecular_function | transferase activity |
| A | 0016765 | molecular_function | transferase activity, transferring alkyl or aryl (other than methyl) groups |
| A | 0016829 | molecular_function | lyase activity |
| A | 0019344 | biological_process | cysteine biosynthetic process |
| B | 0004124 | molecular_function | cysteine synthase activity |
| B | 0008652 | biological_process | amino acid biosynthetic process |
| B | 0016740 | molecular_function | transferase activity |
| B | 0016765 | molecular_function | transferase activity, transferring alkyl or aryl (other than methyl) groups |
| B | 0016829 | molecular_function | lyase activity |
| B | 0019344 | biological_process | cysteine biosynthetic process |
| C | 0004124 | molecular_function | cysteine synthase activity |
| C | 0008652 | biological_process | amino acid biosynthetic process |
| C | 0016740 | molecular_function | transferase activity |
| C | 0016765 | molecular_function | transferase activity, transferring alkyl or aryl (other than methyl) groups |
| C | 0016829 | molecular_function | lyase activity |
| C | 0019344 | biological_process | cysteine biosynthetic process |
| D | 0004124 | molecular_function | cysteine synthase activity |
| D | 0008652 | biological_process | amino acid biosynthetic process |
| D | 0016740 | molecular_function | transferase activity |
| D | 0016765 | molecular_function | transferase activity, transferring alkyl or aryl (other than methyl) groups |
| D | 0016829 | molecular_function | lyase activity |
| D | 0019344 | biological_process | cysteine biosynthetic process |
| E | 0004124 | molecular_function | cysteine synthase activity |
| E | 0008652 | biological_process | amino acid biosynthetic process |
| E | 0016740 | molecular_function | transferase activity |
| E | 0016765 | molecular_function | transferase activity, transferring alkyl or aryl (other than methyl) groups |
| E | 0016829 | molecular_function | lyase activity |
| E | 0019344 | biological_process | cysteine biosynthetic process |
| F | 0004124 | molecular_function | cysteine synthase activity |
| F | 0008652 | biological_process | amino acid biosynthetic process |
| F | 0016740 | molecular_function | transferase activity |
| F | 0016765 | molecular_function | transferase activity, transferring alkyl or aryl (other than methyl) groups |
| F | 0016829 | molecular_function | lyase activity |
| F | 0019344 | biological_process | cysteine biosynthetic process |
| G | 0004124 | molecular_function | cysteine synthase activity |
| G | 0008652 | biological_process | amino acid biosynthetic process |
| G | 0016740 | molecular_function | transferase activity |
| G | 0016765 | molecular_function | transferase activity, transferring alkyl or aryl (other than methyl) groups |
| G | 0016829 | molecular_function | lyase activity |
| G | 0019344 | biological_process | cysteine biosynthetic process |
| H | 0004124 | molecular_function | cysteine synthase activity |
| H | 0008652 | biological_process | amino acid biosynthetic process |
| H | 0016740 | molecular_function | transferase activity |
| H | 0016765 | molecular_function | transferase activity, transferring alkyl or aryl (other than methyl) groups |
| H | 0016829 | molecular_function | lyase activity |
| H | 0019344 | biological_process | cysteine biosynthetic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 17 |
| Details | binding site for residue AA5 A 401 |
| Chain | Residue |
| A | THR69 |
| A | GLY178 |
| A | THR180 |
| A | GLY219 |
| A | ILE220 |
| A | SER263 |
| A | PRO289 |
| A | ASP290 |
| A | TYR295 |
| A | ALA70 |
| A | GLY71 |
| A | ASN72 |
| A | THR73 |
| A | GLN142 |
| A | ALA175 |
| A | GLY176 |
| A | SER177 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 A 402 |
| Chain | Residue |
| A | ARG250 |
| A | HIS251 |
| A | ARG254 |
| A | LYS303 |
| site_id | AC3 |
| Number of Residues | 2 |
| Details | binding site for residue SO4 A 403 |
| Chain | Residue |
| A | GLU21 |
| A | HIS256 |
| site_id | AC4 |
| Number of Residues | 18 |
| Details | binding site for residue AA5 B 401 |
| Chain | Residue |
| B | THR69 |
| B | ALA70 |
| B | GLY71 |
| B | ASN72 |
| B | THR73 |
| B | ILE120 |
| B | GLN142 |
| B | GLY174 |
| B | ALA175 |
| B | GLY176 |
| B | SER177 |
| B | GLY178 |
| B | THR180 |
| B | GLY219 |
| B | SER263 |
| B | PRO289 |
| B | ASP290 |
| B | TYR295 |
| site_id | AC5 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 B 402 |
| Chain | Residue |
| B | ARG250 |
| B | HIS251 |
| B | LYS303 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 B 403 |
| Chain | Residue |
| B | PRO19 |
| B | ILE20 |
| B | GLU21 |
| B | HIS256 |
| site_id | AC7 |
| Number of Residues | 18 |
| Details | binding site for residue AA5 C 401 |
| Chain | Residue |
| C | THR69 |
| C | ALA70 |
| C | GLY71 |
| C | ASN72 |
| C | THR73 |
| C | GLN142 |
| C | ALA175 |
| C | GLY176 |
| C | SER177 |
| C | GLY178 |
| C | GLY179 |
| C | THR180 |
| C | GLY219 |
| C | ILE220 |
| C | SER263 |
| C | PRO289 |
| C | ASP290 |
| C | TYR295 |
| site_id | AC8 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 C 402 |
| Chain | Residue |
| C | ARG250 |
| C | HIS251 |
| C | LYS303 |
| site_id | AC9 |
| Number of Residues | 2 |
| Details | binding site for residue SO4 C 403 |
| Chain | Residue |
| C | GLU21 |
| C | HIS256 |
| site_id | AD1 |
| Number of Residues | 17 |
| Details | binding site for residue AA5 D 401 |
| Chain | Residue |
| D | THR69 |
| D | ALA70 |
| D | ASN72 |
| D | THR73 |
| D | ILE120 |
| D | GLN142 |
| D | GLY174 |
| D | ALA175 |
| D | GLY176 |
| D | SER177 |
| D | GLY178 |
| D | THR180 |
| D | GLY219 |
| D | SER263 |
| D | PRO289 |
| D | ASP290 |
| D | TYR295 |
| site_id | AD2 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 D 402 |
| Chain | Residue |
| D | ARG250 |
| D | HIS251 |
| D | LYS303 |
| site_id | AD3 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 D 403 |
| Chain | Residue |
| D | ILE20 |
| D | GLU21 |
| D | HIS256 |
| site_id | AD4 |
| Number of Residues | 18 |
| Details | binding site for residue AA5 E 401 |
| Chain | Residue |
| E | GLN142 |
| E | ALA175 |
| E | GLY176 |
| E | SER177 |
| E | GLY178 |
| E | GLY179 |
| E | THR180 |
| E | GLY219 |
| E | ILE220 |
| E | SER263 |
| E | PRO289 |
| E | ASP290 |
| E | TYR295 |
| E | THR69 |
| E | ALA70 |
| E | ASN72 |
| E | THR73 |
| E | ILE120 |
| site_id | AD5 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 E 402 |
| Chain | Residue |
| E | ARG250 |
| E | HIS251 |
| E | LYS303 |
| site_id | AD6 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 E 403 |
| Chain | Residue |
| E | ILE20 |
| E | GLU21 |
| E | HIS256 |
| site_id | AD7 |
| Number of Residues | 19 |
| Details | binding site for residue AA5 F 401 |
| Chain | Residue |
| F | THR69 |
| F | ALA70 |
| F | ASN72 |
| F | THR73 |
| F | ILE120 |
| F | GLN142 |
| F | ALA175 |
| F | GLY176 |
| F | SER177 |
| F | GLY178 |
| F | GLY179 |
| F | THR180 |
| F | GLY219 |
| F | ILE220 |
| F | GLY221 |
| F | SER263 |
| F | PRO289 |
| F | ASP290 |
| F | TYR295 |
| site_id | AD8 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 F 402 |
| Chain | Residue |
| F | ARG250 |
| F | HIS251 |
| F | LYS303 |
| site_id | AD9 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 F 403 |
| Chain | Residue |
| F | ILE20 |
| F | GLU21 |
| F | HIS256 |
| site_id | AE1 |
| Number of Residues | 18 |
| Details | binding site for residue AA5 G 401 |
| Chain | Residue |
| G | THR69 |
| G | ALA70 |
| G | GLY71 |
| G | ASN72 |
| G | THR73 |
| G | LYS100 |
| G | GLN142 |
| G | GLY174 |
| G | ALA175 |
| G | GLY176 |
| G | SER177 |
| G | GLY178 |
| G | THR180 |
| G | GLY219 |
| G | SER263 |
| G | PRO289 |
| G | ASP290 |
| G | TYR295 |
| site_id | AE2 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 G 402 |
| Chain | Residue |
| G | ARG250 |
| G | HIS251 |
| G | LYS303 |
| site_id | AE3 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 G 403 |
| Chain | Residue |
| G | ILE20 |
| G | GLU21 |
| G | HIS256 |
| site_id | AE4 |
| Number of Residues | 16 |
| Details | binding site for residue AA5 H 401 |
| Chain | Residue |
| H | THR69 |
| H | ALA70 |
| H | ASN72 |
| H | THR73 |
| H | GLN142 |
| H | PHE143 |
| H | TYR152 |
| H | GLY176 |
| H | SER177 |
| H | GLY178 |
| H | GLY179 |
| H | THR180 |
| H | GLY219 |
| H | GLY221 |
| H | SER263 |
| H | PRO289 |
| site_id | AE5 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 H 402 |
| Chain | Residue |
| H | ARG250 |
| H | HIS251 |
| H | LYS303 |
| site_id | AE6 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 H 403 |
| Chain | Residue |
| H | ILE20 |
| H | HIS251 |
| H | HIS256 |
