5B1I
Crystal structure of K42A mutant of cystathionine beta-synthase from Lactobacillus plantarum in a complex with L-methionine
Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0004122 | molecular_function | cystathionine beta-synthase activity |
A | 0005737 | cellular_component | cytoplasm |
A | 0016765 | molecular_function | transferase activity, transferring alkyl or aryl (other than methyl) groups |
A | 0016829 | molecular_function | lyase activity |
A | 0019344 | biological_process | cysteine biosynthetic process |
B | 0004122 | molecular_function | cystathionine beta-synthase activity |
B | 0005737 | cellular_component | cytoplasm |
B | 0016765 | molecular_function | transferase activity, transferring alkyl or aryl (other than methyl) groups |
B | 0016829 | molecular_function | lyase activity |
B | 0019344 | biological_process | cysteine biosynthetic process |
C | 0004122 | molecular_function | cystathionine beta-synthase activity |
C | 0005737 | cellular_component | cytoplasm |
C | 0016765 | molecular_function | transferase activity, transferring alkyl or aryl (other than methyl) groups |
C | 0016829 | molecular_function | lyase activity |
C | 0019344 | biological_process | cysteine biosynthetic process |
D | 0004122 | molecular_function | cystathionine beta-synthase activity |
D | 0005737 | cellular_component | cytoplasm |
D | 0016765 | molecular_function | transferase activity, transferring alkyl or aryl (other than methyl) groups |
D | 0016829 | molecular_function | lyase activity |
D | 0019344 | biological_process | cysteine biosynthetic process |
E | 0004122 | molecular_function | cystathionine beta-synthase activity |
E | 0005737 | cellular_component | cytoplasm |
E | 0016765 | molecular_function | transferase activity, transferring alkyl or aryl (other than methyl) groups |
E | 0016829 | molecular_function | lyase activity |
E | 0019344 | biological_process | cysteine biosynthetic process |
F | 0004122 | molecular_function | cystathionine beta-synthase activity |
F | 0005737 | cellular_component | cytoplasm |
F | 0016765 | molecular_function | transferase activity, transferring alkyl or aryl (other than methyl) groups |
F | 0016829 | molecular_function | lyase activity |
F | 0019344 | biological_process | cysteine biosynthetic process |
G | 0004122 | molecular_function | cystathionine beta-synthase activity |
G | 0005737 | cellular_component | cytoplasm |
G | 0016765 | molecular_function | transferase activity, transferring alkyl or aryl (other than methyl) groups |
G | 0016829 | molecular_function | lyase activity |
G | 0019344 | biological_process | cysteine biosynthetic process |
H | 0004122 | molecular_function | cystathionine beta-synthase activity |
H | 0005737 | cellular_component | cytoplasm |
H | 0016765 | molecular_function | transferase activity, transferring alkyl or aryl (other than methyl) groups |
H | 0016829 | molecular_function | lyase activity |
H | 0019344 | biological_process | cysteine biosynthetic process |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 17 |
Details | binding site for residue AA5 A 401 |
Chain | Residue |
A | THR69 |
A | GLY178 |
A | THR180 |
A | GLY219 |
A | ILE220 |
A | SER263 |
A | PRO289 |
A | ASP290 |
A | TYR295 |
A | ALA70 |
A | GLY71 |
A | ASN72 |
A | THR73 |
A | GLN142 |
A | ALA175 |
A | GLY176 |
A | SER177 |
site_id | AC2 |
Number of Residues | 4 |
Details | binding site for residue SO4 A 402 |
Chain | Residue |
A | ARG250 |
A | HIS251 |
A | ARG254 |
A | LYS303 |
site_id | AC3 |
Number of Residues | 2 |
Details | binding site for residue SO4 A 403 |
Chain | Residue |
A | GLU21 |
A | HIS256 |
site_id | AC4 |
Number of Residues | 18 |
Details | binding site for residue AA5 B 401 |
Chain | Residue |
B | THR69 |
B | ALA70 |
B | GLY71 |
B | ASN72 |
B | THR73 |
B | ILE120 |
B | GLN142 |
B | GLY174 |
B | ALA175 |
B | GLY176 |
B | SER177 |
B | GLY178 |
B | THR180 |
B | GLY219 |
B | SER263 |
B | PRO289 |
B | ASP290 |
B | TYR295 |
site_id | AC5 |
Number of Residues | 3 |
Details | binding site for residue SO4 B 402 |
Chain | Residue |
B | ARG250 |
B | HIS251 |
B | LYS303 |
site_id | AC6 |
Number of Residues | 4 |
Details | binding site for residue SO4 B 403 |
Chain | Residue |
B | PRO19 |
B | ILE20 |
B | GLU21 |
B | HIS256 |
site_id | AC7 |
Number of Residues | 18 |
Details | binding site for residue AA5 C 401 |
Chain | Residue |
C | THR69 |
C | ALA70 |
C | GLY71 |
C | ASN72 |
C | THR73 |
C | GLN142 |
C | ALA175 |
C | GLY176 |
C | SER177 |
C | GLY178 |
C | GLY179 |
C | THR180 |
C | GLY219 |
C | ILE220 |
C | SER263 |
C | PRO289 |
C | ASP290 |
C | TYR295 |
site_id | AC8 |
Number of Residues | 3 |
Details | binding site for residue SO4 C 402 |
Chain | Residue |
C | ARG250 |
C | HIS251 |
C | LYS303 |
site_id | AC9 |
Number of Residues | 2 |
Details | binding site for residue SO4 C 403 |
Chain | Residue |
C | GLU21 |
C | HIS256 |
site_id | AD1 |
Number of Residues | 17 |
Details | binding site for residue AA5 D 401 |
Chain | Residue |
D | THR69 |
D | ALA70 |
D | ASN72 |
D | THR73 |
D | ILE120 |
D | GLN142 |
D | GLY174 |
D | ALA175 |
D | GLY176 |
D | SER177 |
D | GLY178 |
D | THR180 |
D | GLY219 |
D | SER263 |
D | PRO289 |
D | ASP290 |
D | TYR295 |
site_id | AD2 |
Number of Residues | 3 |
Details | binding site for residue SO4 D 402 |
Chain | Residue |
D | ARG250 |
D | HIS251 |
D | LYS303 |
site_id | AD3 |
Number of Residues | 3 |
Details | binding site for residue SO4 D 403 |
Chain | Residue |
D | ILE20 |
D | GLU21 |
D | HIS256 |
site_id | AD4 |
Number of Residues | 18 |
Details | binding site for residue AA5 E 401 |
Chain | Residue |
E | GLN142 |
E | ALA175 |
E | GLY176 |
E | SER177 |
E | GLY178 |
E | GLY179 |
E | THR180 |
E | GLY219 |
E | ILE220 |
E | SER263 |
E | PRO289 |
E | ASP290 |
E | TYR295 |
E | THR69 |
E | ALA70 |
E | ASN72 |
E | THR73 |
E | ILE120 |
site_id | AD5 |
Number of Residues | 3 |
Details | binding site for residue SO4 E 402 |
Chain | Residue |
E | ARG250 |
E | HIS251 |
E | LYS303 |
site_id | AD6 |
Number of Residues | 3 |
Details | binding site for residue SO4 E 403 |
Chain | Residue |
E | ILE20 |
E | GLU21 |
E | HIS256 |
site_id | AD7 |
Number of Residues | 19 |
Details | binding site for residue AA5 F 401 |
Chain | Residue |
F | THR69 |
F | ALA70 |
F | ASN72 |
F | THR73 |
F | ILE120 |
F | GLN142 |
F | ALA175 |
F | GLY176 |
F | SER177 |
F | GLY178 |
F | GLY179 |
F | THR180 |
F | GLY219 |
F | ILE220 |
F | GLY221 |
F | SER263 |
F | PRO289 |
F | ASP290 |
F | TYR295 |
site_id | AD8 |
Number of Residues | 3 |
Details | binding site for residue SO4 F 402 |
Chain | Residue |
F | ARG250 |
F | HIS251 |
F | LYS303 |
site_id | AD9 |
Number of Residues | 3 |
Details | binding site for residue SO4 F 403 |
Chain | Residue |
F | ILE20 |
F | GLU21 |
F | HIS256 |
site_id | AE1 |
Number of Residues | 18 |
Details | binding site for residue AA5 G 401 |
Chain | Residue |
G | THR69 |
G | ALA70 |
G | GLY71 |
G | ASN72 |
G | THR73 |
G | LYS100 |
G | GLN142 |
G | GLY174 |
G | ALA175 |
G | GLY176 |
G | SER177 |
G | GLY178 |
G | THR180 |
G | GLY219 |
G | SER263 |
G | PRO289 |
G | ASP290 |
G | TYR295 |
site_id | AE2 |
Number of Residues | 3 |
Details | binding site for residue SO4 G 402 |
Chain | Residue |
G | ARG250 |
G | HIS251 |
G | LYS303 |
site_id | AE3 |
Number of Residues | 3 |
Details | binding site for residue SO4 G 403 |
Chain | Residue |
G | ILE20 |
G | GLU21 |
G | HIS256 |
site_id | AE4 |
Number of Residues | 16 |
Details | binding site for residue AA5 H 401 |
Chain | Residue |
H | THR69 |
H | ALA70 |
H | ASN72 |
H | THR73 |
H | GLN142 |
H | PHE143 |
H | TYR152 |
H | GLY176 |
H | SER177 |
H | GLY178 |
H | GLY179 |
H | THR180 |
H | GLY219 |
H | GLY221 |
H | SER263 |
H | PRO289 |
site_id | AE5 |
Number of Residues | 3 |
Details | binding site for residue SO4 H 402 |
Chain | Residue |
H | ARG250 |
H | HIS251 |
H | LYS303 |
site_id | AE6 |
Number of Residues | 3 |
Details | binding site for residue SO4 H 403 |
Chain | Residue |
H | ILE20 |
H | HIS251 |
H | HIS256 |