5AYN

Crystal structure of a bacterial homologue of iron transporter ferroportin in outward-facing state

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005381	molecular_function	iron ion transmembrane transporter activity
A	0005886	cellular_component	plasma membrane
A	0016020	cellular_component	membrane
A	0034755	biological_process	iron ion transmembrane transport
A	0046872	molecular_function	metal ion binding
A	0055085	biological_process	transmembrane transport

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	binding site for residue K A 501

Chain	Residue
A	THR20
A	ASP24
A	ASN196
A	SER199
A	PHE200

---

site_id	AC2
Number of Residues	3
Details	binding site for residue OLC A 502

Chain	Residue
A	TYR204
A	ARG208
A	TYR404

---

site_id	AC3
Number of Residues	5
Details	binding site for residue OLC A 503

Chain	Residue
A	LYS42
A	LEU112
A	SER113
A	PHE116
A	PHE39

---

site_id	AC4
Number of Residues	4
Details	binding site for residue OLC A 504

Chain	Residue
A	LEU305
A	TRP313
A	HIS314
A	PHE317

---

site_id	AC5
Number of Residues	6
Details	binding site for residue OLC A 505

Chain	Residue
A	SER309
A	ARG312
A	TRP313
A	GLY316
A	PHE317
A	ILE324

---

site_id	AC6
Number of Residues	1
Details	binding site for residue OLC A 506

Chain	Residue
A	PHE86

---

site_id	AC7
Number of Residues	3
Details	binding site for residue OLC A 507

Chain	Residue
A	PHE290
A	CYS343
A	OLC508

---

site_id	AC8
Number of Residues	6
Details	binding site for residue OLC A 508

Chain	Residue
A	GLY215
A	GLU279
A	PHE283
A	TYR338
A	OLC507
A	OLC509

---

site_id	AC9
Number of Residues	6
Details	binding site for residue OLC A 509

Chain	Residue
A	GLY100
A	ALA104
A	LYS217
A	LYS219
A	OLC508
A	HOH653

---

site_id	AD1
Number of Residues	5
Details	binding site for residue OLC A 510

Chain	Residue
A	GLN12
A	LEU206
A	ASN209
A	SER391
A	SER394

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	29
Details	Transmembrane: {"description":"Helical; Name=1","evidences":[{"source":"PubMed","id":"26461048","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5AYN","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	19
Details	Topological domain: {"description":"Extracellular","evidences":[{"source":"PubMed","id":"26461048","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	26
Details	Transmembrane: {"description":"Helical; Name=2","evidences":[{"source":"PubMed","id":"26461048","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5AYN","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	8
Details	Topological domain: {"description":"Cytoplasmic","evidences":[{"source":"PubMed","id":"26461048","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	30
Details	Transmembrane: {"description":"Helical; Name=3","evidences":[{"source":"PubMed","id":"26461048","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5AYN","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI6
Number of Residues	35
Details	Transmembrane: {"description":"Helical; Name=4","evidences":[{"source":"PubMed","id":"26461048","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5AYN","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI7
Number of Residues	28
Details	Transmembrane: {"description":"Helical; Name=5","evidences":[{"source":"PubMed","id":"26461048","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5AYN","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI8
Number of Residues	26
Details	Transmembrane: {"description":"Helical; Name=6","evidences":[{"source":"PubMed","id":"26461048","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5AYN","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI9
Number of Residues	28
Details	Transmembrane: {"description":"Helical; Name=7","evidences":[{"source":"PubMed","id":"26461048","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5AYN","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI10
Number of Residues	27
Details	Transmembrane: {"description":"Helical; Name=8","evidences":[{"source":"PubMed","id":"26461048","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5AYN","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI11
Number of Residues	22
Details	Transmembrane: {"description":"Helical; Name=9","evidences":[{"source":"PubMed","id":"26461048","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5AYN","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI12
Number of Residues	29
Details	Transmembrane: {"description":"Helical; Name=10","evidences":[{"source":"PubMed","id":"26461048","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5AYN","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI13
Number of Residues	24
Details	Transmembrane: {"description":"Helical; Name=11","evidences":[{"source":"PubMed","id":"26461048","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5AYN","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI14
Number of Residues	25
Details	Transmembrane: {"description":"Helical; Name=12","evidences":[{"source":"PubMed","id":"26461048","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5AYN","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI15
Number of Residues	4
Details	Binding site: {"evidences":[{"source":"PubMed","id":"30082682","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"6BTX","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---