5AX0

Crystal Structure of the Cell-Free Synthesized Membrane Protein, Acetabularia Rhodopsin I, at 1.52 angstrom

Replaces:  3WT9
?

Functional Information from GO Data

ChainGOidnamespacecontents
A0016021cellular_componentintegral component of membrane
A0005216molecular_functionion channel activity
?

Functional Information from PDB Data

site_idNumber of ResiduesDetails
AC18binding site for residue RET A 301
ChainResidue
ATRP90
AMET122
AGLY144
ATRP185
ATYR188
APRO189
AASP214
ALYS218

AC29binding site for residue OLB A 302
ChainResidue
AALA58
AASN65
ALYS70
ATYR84
AALA85
AILE88
APHE92
AD10309
AHOH465

AC35binding site for residue OLB A 303
ChainResidue
ALEU11
AVAL183
AVAL205
AILE208
AC14307

AC47binding site for residue OLB A 304
ChainResidue
APRO95
ALEU96
AVAL102
ATHR105
AASN106
AMET107
ALYS166

AC53binding site for residue D12 A 305
ChainResidue
AGLN35
ATRP114
AALA121

AC61binding site for residue C14 A 307
ChainResidue
AOLB303

AC72binding site for residue R16 A 308
ChainResidue
ATRP138
APHE141

AC83binding site for residue D10 A 309
ChainResidue
ATHR53
ATHR57
AOLB302

?

Functional Information from PDB atom coordinates for the "HETATM" binding sites

site_idNumber of ResiduesDetails
OLB_5ax0_A_30313(2S)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate binding site
ChainResidueligand
AASN5OLB: (2S)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate
ALEU11OLB: (2S)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate
ATYR180OLB: (2S)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate
AVAL183-LEU184OLB: (2S)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate
AILE187OLB: (2S)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate
AASP204-VAL205OLB: (2S)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate
AILE208-ALA209OLB: (2S)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate
AILE212-LEU213OLB: (2S)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate
ALEU216OLB: (2S)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate

D10_5ax0_A_3107DECANE binding site
ChainResidueligand
AVAL22D10: DECANE
AILE212D10: DECANE
ALEU215-LEU216D10: DECANE
APRO219-LEU220D10: DECANE
AILE223D10: DECANE

D12_5ax0_A_3053DODECANE binding site
ChainResidueligand
AILE32D12: DODECANE
AGLN35-PHE36D12: DODECANE

D10_5ax0_A_3096DECANE binding site
ChainResidueligand
ATYR46D10: DECANE
AILE49-ALA50D10: DECANE
ATHR53-ILE54D10: DECANE
ATHR57D10: DECANE

OLB_5ax0_A_30213(2S)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate binding site
ChainResidueligand
AILE54OLB: (2S)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate
ATHR57-ALA58OLB: (2S)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate
AALA61OLB: (2S)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate
AASN65OLB: (2S)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate
AASP68OLB: (2S)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate
ALYS70-PRO71OLB: (2S)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate
ATYR84-ALA85OLB: (2S)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate
AILE88-ASP89OLB: (2S)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate
APHE92OLB: (2S)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate

RET_5ax0_A_30121RETINAL binding site
ChainResidueligand
ATYR87RET: RETINAL
AASP89-TRP90RET: RETINAL
ATHR93-THR94RET: RETINAL
ALEU97RET: RETINAL
AMET122-ILE123RET: RETINAL
APHE125-GLY126RET: RETINAL
APHE141RET: RETINAL
AGLY144-CYS145RET: RETINAL
ALEU148RET: RETINAL
ATRP185RET: RETINAL
ATYR188-PRO189RET: RETINAL
ATRP192RET: RETINAL
AASP214RET: RETINAL
AALA217-LYS218RET: RETINAL

OLB_5ax0_A_30415(2S)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate binding site
ChainResidueligand
AVAL91-PHE92OLB: (2S)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate
APRO95-LEU96OLB: (2S)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate
ALEU99OLB: (2S)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate
AVAL102-LEU103OLB: (2S)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate
ATHR105-PRO108OLB: (2S)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate
AILE112OLB: (2S)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate
AMET116OLB: (2S)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate
AILE120OLB: (2S)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate
ALYS166OLB: (2S)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate

R16_5ax0_A_3086HEXADECANE binding site
ChainResidueligand
ATRP138R16: HEXADECANE
APHE141-VAL142R16: HEXADECANE
ACYS145-ILE146R16: HEXADECANE
AALA149R16: HEXADECANE

D12_5ax0_A_30610DODECANE binding site
ChainResidueligand
ATRP138D12: DODECANE
APHE141D12: DODECANE
ACYS145D12: DODECANE
ALEU148D12: DODECANE
AVAL186D12: DODECANE
APRO189-ILE190D12: DODECANE
AGLY193-LEU194D12: DODECANE
AILE200D12: DODECANE

C14_5ax0_A_3074TETRADECANE binding site
ChainResidueligand
ATYR180C14: TETRADECANE
AILE212C14: TETRADECANE
ALEU216C14: TETRADECANE
ALEU220C14: TETRADECANE

?

Functional Information from PROSITE/UniProt

site_idNumber of ResiduesDetails
?

Functional Information from SwissProt/UniProt

site_idNumber of ResiduesDetails
SWS_FT_FI1158Helical. {ECO:0000256|SAM:Phobius}.
ChainResidueDetails
AALA22-PHE43
ALEU50-ALA70
AILE90-LEU111
AMET118-THR139
ATRP145-ILE163
ALEU184-ILE208
AILE214-TYR240

?

Catalytic Information from CSA

site_idNumber of ResiduesDetails
PDBj@FacebookPDBj@TwitterwwPDBwwPDB FoundationEM DataBank

Copyright © 2013-2018 Protein Data Bank Japan