5AWT
Crystal structure of the SGIP1 mu homology domain in complex with an Eps15 fragment containing two DPF motifs (YDPFGGDPFKG)
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0072583 | biological_process | clathrin-dependent endocytosis |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 2 |
| Details | binding site for residue ZN A 901 |
| Chain | Residue |
| A | ASP558 |
| A | HIS601 |
| site_id | AC2 |
| Number of Residues | 3 |
| Details | binding site for residue ZN A 902 |
| Chain | Residue |
| A | GLU589 |
| A | ASP672 |
| A | HOH1032 |
| site_id | AC3 |
| Number of Residues | 2 |
| Details | binding site for residue ZN A 903 |
| Chain | Residue |
| A | HIS655 |
| A | HOH1031 |
| site_id | AC4 |
| Number of Residues | 3 |
| Details | binding site for residue ZN A 904 |
| Chain | Residue |
| A | HOH1004 |
| A | HIS623 |
| A | ASP639 |
| site_id | AC5 |
| Number of Residues | 3 |
| Details | binding site for residue ZN A 905 |
| Chain | Residue |
| A | HIS623 |
| A | GLU644 |
| A | GLN677 |
| site_id | AC6 |
| Number of Residues | 1 |
| Details | binding site for residue ZN A 906 |
| Chain | Residue |
| A | ASP758 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 8 |
| Details | Region: {"description":"Interaction with DPF motifs-containing proteins","evidences":[{"source":"PubMed","id":"26822536","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5AWU","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 179 |
| Details | Region: {"description":"Necessary and sufficient to mediate interaction with CANX","evidences":[{"source":"UniProtKB","id":"Q8VD37","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 8 |
| Details | Region: {"description":"Interaction with DPF motifs-containing proteins","evidences":[{"source":"PubMed","id":"26822536","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5AWT","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5AWU","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | Repeat: {"description":"5"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 2 |
| Details | Repeat: {"description":"6"} |
| Chain | Residue | Details |
