5AR6

crystal structure of porcine RNase 4

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003676	molecular_function	nucleic acid binding
A	0004518	molecular_function	nuclease activity
A	0004519	molecular_function	endonuclease activity
A	0004540	molecular_function	RNA nuclease activity
A	0005576	cellular_component	extracellular region
A	0005615	cellular_component	extracellular space
A	0016787	molecular_function	hydrolase activity
A	0019731	biological_process	antibacterial humoral response
A	0042742	biological_process	defense response to bacterium
A	0050830	biological_process	defense response to Gram-positive bacterium

Functional Information from PDB Data

site_id	AC1
Number of Residues	7
Details	BINDING SITE FOR RESIDUE EDO A 1120

Chain	Residue
A	LEU9
A	VAL13
A	PRO15
A	SER36
A	PRO90
A	HOH315
A	HOH332

---

site_id	AC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE EDO A 1121

Chain	Residue
A	MET69
A	ASN70
A	HIS37
A	GLN68

---

Functional Information from PROSITE/UniProt

site_id	PS00127
Number of Residues	7
Details	RNASE_PANCREATIC Pancreatic ribonuclease family signature. CKrfNTF

Chain	Residue	Details
A	CYS39-PHE45

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	Active site: {"description":"Proton acceptor","evidences":[{"source":"UniProtKB","id":"Q9H1E1","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	1
Details	Active site: {"description":"Proton donor","evidences":[{"source":"UniProtKB","id":"Q9H1E1","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	6
Details	Binding site: {"evidences":[{"source":"PubMed","id":"26748441","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5ARK","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	1
Details	Modified residue: {"description":"Pyrrolidone carboxylic acid","evidences":[{"source":"UniProtKB","id":"P15467","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

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