5AP9

Controlled lid-opening in Thermomyces lanuginosus lipase - a switch for activity and binding

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004806	molecular_function	triacylglycerol lipase activity
A	0006629	biological_process	lipid metabolic process
A	0016042	biological_process	lipid catabolic process
A	0016787	molecular_function	hydrolase activity
B	0004806	molecular_function	triacylglycerol lipase activity
B	0006629	biological_process	lipid metabolic process
B	0016042	biological_process	lipid catabolic process
B	0016787	molecular_function	hydrolase activity

Functional Information from PROSITE/UniProt

site_id	PS00120
Number of Residues	10
Details	LIPASE_SER Lipases, serine active site. VVFTGHSLGG

Chain	Residue	Details
A	VAL140-GLY149

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	ACT_SITE: Nucleophile => ECO:0000269|PubMed:8014587

Chain	Residue	Details
A	SER146
B	SER146

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site_id	SWS_FT_FI2
Number of Residues	4
Details	ACT_SITE: Charge relay system => ECO:0000305|PubMed:8014587

Chain	Residue	Details
A	ASP201
A	HIS258
B	ASP201
B	HIS258

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