5AOD

Crystal structure of wild type pneumolysin.

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005576	cellular_component	extracellular region
A	0005737	cellular_component	cytoplasm
A	0008289	molecular_function	lipid binding
A	0015485	molecular_function	cholesterol binding
A	0016020	cellular_component	membrane
A	0020002	cellular_component	host cell plasma membrane
A	0031640	biological_process	killing of cells of another organism
A	0035821	biological_process	modulation of process of another organism
A	0090729	molecular_function	toxin activity

Functional Information from PROSITE/UniProt

site_id	PS00481
Number of Residues	12
Details	THIOL_CYTOLYSINS Thiol-activated cytolysins signature. RECTGLaWEWWR

Chain	Residue	Details
A	ARG426-ARG437

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	43
Details	TRANSMEM: Beta stranded => ECO:0000250|UniProtKB:Q04IN8

Chain	Residue	Details
A	MET158-LYS171
A	ILE178-GLU187
A	SER256-ALA265
A	ALA273-THR285

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