Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000105 | biological_process | L-histidine biosynthetic process |
| A | 0003949 | molecular_function | 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide isomerase activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005829 | cellular_component | cytosol |
| A | 0008652 | biological_process | amino acid biosynthetic process |
| A | 0016853 | molecular_function | isomerase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE PO4 A 1245 |
| Chain | Residue |
| A | GLY81 |
| A | ARG83 |
| A | GLY102 |
| A | SER103 |
| A | HOH2042 |
| A | HOH2043 |
| A | HOH2114 |
| site_id | AC2 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE PO4 A 1246 |
| Chain | Residue |
| A | HOH2097 |
| A | GLY225 |
| A | ARG226 |
| site_id | AC3 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE PO4 A 1247 |
| Chain | Residue |
| A | LYS138 |
| A | LYS138 |
| A | GLU154 |
| A | GLU154 |
| A | GLU189 |
| A | ARG193 |
| A | HOH2079 |
| A | HOH2089 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE NA A 1248 |
| Chain | Residue |
| A | ALA5 |
| A | GLY225 |
| A | LEU229 |
| A | HOH2006 |
| A | HOH2007 |
| site_id | AC5 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE EPE A 1249 |
| Chain | Residue |
| A | MET1 |
| A | ARG131 |
| A | GLN139 |
| A | GLU147 |
| A | ASN148 |
| A | GLY150 |
| A | ARG220 |
| A | GLN243 |
| A | HOH2073 |
| site_id | AC6 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE GOL A 1250 |
| Chain | Residue |
| A | ASP110 |
| A | LYS113 |
| A | PHE119 |
| A | GLN122 |
| A | GOL1251 |
| site_id | AC7 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE GOL A 1251 |
| Chain | Residue |
| A | ALA97 |
| A | VAL106 |
| A | PRO109 |
| A | GLN122 |
| A | LEU156 |
| A | GOL1250 |
| A | HOH2077 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | Active site: {"description":"Proton acceptor","evidences":[{"evidenceCode":"ECO:0000250"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | Active site: {"description":"Proton donor","evidences":[{"evidenceCode":"ECO:0000250"}]} |
