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5AH3

Crystal structure of the Mep2 mutant R452D,S453D from Candida albicans

Functional Information from GO Data
ChainGOidnamespacecontents
A0005886cellular_componentplasma membrane
A0006995biological_processcellular response to nitrogen starvation
A0007155biological_processcell adhesion
A0008519molecular_functionammonium channel activity
A0009267biological_processcellular response to starvation
A0016020cellular_componentmembrane
A0030447biological_processfilamentous growth
A0036170biological_processfilamentous growth of a population of unicellular organisms in response to starvation
A0044406biological_processadhesion of symbiont to host
A0072488biological_processammonium transmembrane transport
A1900445biological_processpositive regulation of filamentous growth of a population of unicellular organisms in response to biotic stimulus
Functional Information from PDB Data
site_idAC1
Number of Residues9
DetailsBINDING SITE FOR RESIDUE DMU A 500
ChainResidue
AARG143
ALEU144
AGLY145
APRO146
AVAL149
ATRP274
ATRP281
AGLU449
APRO450

site_idAC2
Number of Residues4
DetailsBINDING SITE FOR RESIDUE DMU A 501
ChainResidue
ALYS16
ATRP373
AMET374
AHIS376

site_idAC3
Number of Residues4
DetailsBINDING SITE FOR RESIDUE DMU A 503
ChainResidue
APHE92
ATRP172
AALA390
ADMU504

site_idAC4
Number of Residues1
DetailsBINDING SITE FOR RESIDUE DMU A 504
ChainResidue
ADMU503

Functional Information from PROSITE/UniProt
site_idPS01219
Number of Residues26
DetailsAMMONIUM_TRANSP Ammonium transporters signature. DFAGGgpVhenSGfaALaysLWlGkR
ChainResidueDetails
AASP180-ARG205

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PDB entries from 2024-11-13

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