5AGS
Crystal structure of the LeuRS editing domain of Mycobacterium tuberculosis in complex with the adduct 3-(Aminomethyl)-4-bromo-7-ethoxybenzo[c][1,2]oxaborol-1(3H)-ol-AMP
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0002161 | molecular_function | aminoacyl-tRNA editing activity |
| A | 0004823 | molecular_function | leucine-tRNA ligase activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0006418 | biological_process | tRNA aminoacylation for protein translation |
| A | 0006429 | biological_process | leucyl-tRNA aminoacylation |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 20 |
| Details | BINDING SITE FOR RESIDUE 38Y A 1514 |
| Chain | Residue |
| A | PHE335 |
| A | ILE440 |
| A | MET441 |
| A | HIS446 |
| A | ASP447 |
| A | ARG449 |
| A | ASP450 |
| A | HOH2014 |
| A | HOH2131 |
| A | HOH2148 |
| A | HOH2150 |
| A | THR336 |
| A | HOH2272 |
| A | THR337 |
| A | ARG338 |
| A | THR341 |
| A | TYR430 |
| A | VAL431 |
| A | LEU432 |
| A | TYR435 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MET A 1515 |
| Chain | Residue |
| A | PRO417 |
| A | LEU503 |
| A | ALA506 |
| A | HOH2107 |
| A | HOH2256 |
| A | HOH2275 |
