5AGR
Crystal structure of the LeuRS editing domain of Mycobacterium tuberculosis in complex with the adduct (S)-3-(Aminomethyl)-7-ethoxybenzo[c][1,2]oxaborol-1(3H)-ol-AMP
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0002161 | molecular_function | aminoacyl-tRNA deacylase activity |
| A | 0004823 | molecular_function | leucine-tRNA ligase activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0006418 | biological_process | tRNA aminoacylation for protein translation |
| A | 0006429 | biological_process | leucyl-tRNA aminoacylation |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 18 |
| Details | BINDING SITE FOR RESIDUE A52 A 1514 |
| Chain | Residue |
| A | PHE335 |
| A | MET441 |
| A | HIS446 |
| A | ASP447 |
| A | ARG449 |
| A | ASP450 |
| A | HOH2015 |
| A | HOH2114 |
| A | HOH2137 |
| A | HOH2138 |
| A | THR336 |
| A | THR337 |
| A | ARG338 |
| A | TYR430 |
| A | VAL431 |
| A | LEU432 |
| A | TYR435 |
| A | ILE440 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO A 1515 |
| Chain | Residue |
| A | ASP331 |
| A | ILE332 |
| A | GLU333 |
| A | HIS354 |
| A | GLN400 |
| A | THR437 |
| site_id | AC3 |
| Number of Residues | 9 |
| Details | Binding site for Di-peptide MET A 1 and LEU A 2 |
| Chain | Residue |
| A | SER319 |
| A | ILE415 |
| A | PRO417 |
| A | GLY420 |
| A | ARG502 |
| A | ALA506 |
| A | HOH2006 |
| A | HOH2237 |
| A | HOH2238 |
