Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004517 | molecular_function | nitric-oxide synthase activity |
| A | 0006809 | biological_process | nitric oxide biosynthetic process |
| B | 0004517 | molecular_function | nitric-oxide synthase activity |
| B | 0006809 | biological_process | nitric oxide biosynthetic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 15 |
| Details | BINDING SITE FOR RESIDUE HEM A 750 |
| Chain | Residue |
| A | TRP414 |
| A | TYR711 |
| A | H4B760 |
| A | XEB800 |
| A | HOH2369 |
| A | HOH2370 |
| A | HOH2371 |
| A | ARG419 |
| A | CYS420 |
| A | PHE589 |
| A | SER590 |
| A | TRP592 |
| A | GLU597 |
| A | TRP683 |
| A | PHE709 |
| site_id | AC2 |
| Number of Residues | 16 |
| Details | BINDING SITE FOR RESIDUE H4B A 760 |
| Chain | Residue |
| A | SER339 |
| A | MET341 |
| A | ARG601 |
| A | VAL682 |
| A | TRP683 |
| A | HEM750 |
| A | HOH2030 |
| A | HOH2302 |
| A | HOH2351 |
| A | HOH2371 |
| A | HOH2372 |
| B | TRP681 |
| B | PHE696 |
| B | HIS697 |
| B | GLN698 |
| B | GLU699 |
| site_id | AC3 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE XEB A 800 |
| Chain | Residue |
| A | PRO570 |
| A | VAL572 |
| A | ASN574 |
| A | TRP592 |
| A | TYR593 |
| A | GLU597 |
| A | TYR711 |
| A | HEM750 |
| site_id | AC4 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE GOL A 880 |
| Chain | Residue |
| A | ALA679 |
| A | ASP680 |
| A | TRP681 |
| A | MET700 |
| A | ASN702 |
| A | HOH2027 |
| B | CYS336 |
| B | MET337 |
| B | GLY338 |
| B | SER339 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN A 900 |
| Chain | Residue |
| A | CYS331 |
| A | CYS336 |
| B | CYS331 |
| B | CYS336 |
| site_id | AC6 |
| Number of Residues | 15 |
| Details | BINDING SITE FOR RESIDUE HEM B 750 |
| Chain | Residue |
| B | TRP414 |
| B | ARG419 |
| B | CYS420 |
| B | SER462 |
| B | PHE589 |
| B | SER590 |
| B | TRP592 |
| B | GLU597 |
| B | TRP683 |
| B | PHE709 |
| B | TYR711 |
| B | H4B760 |
| B | XEB800 |
| B | HOH2273 |
| B | HOH2274 |
| site_id | AC7 |
| Number of Residues | 15 |
| Details | BINDING SITE FOR RESIDUE H4B B 760 |
| Chain | Residue |
| A | TRP681 |
| A | PHE696 |
| A | HIS697 |
| A | GLN698 |
| A | GLU699 |
| A | HOH2356 |
| B | SER339 |
| B | ARG601 |
| B | VAL682 |
| B | TRP683 |
| B | HEM750 |
| B | HOH2018 |
| B | HOH2224 |
| B | HOH2262 |
| B | HOH2274 |
| site_id | AC8 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE XEB B 800 |
| Chain | Residue |
| B | PRO570 |
| B | VAL572 |
| B | ASN574 |
| B | PHE589 |
| B | TRP592 |
| B | TYR593 |
| B | GLU597 |
| B | HEM750 |
| B | HOH2274 |
| site_id | AC9 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE XEB B 801 |
| Chain | Residue |
| B | ASP394 |
| B | PHE360 |
| B | LYS364 |
| B | MET383 |
| B | LEU386 |
| B | GLU387 |
| B | ASN390 |
| B | ILE393 |
Functional Information from PROSITE/UniProt
| site_id | PS60001 |
| Number of Residues | 8 |
| Details | NOS Nitric oxide synthase (NOS) signature. RCVGRIqW |
| Chain | Residue | Details |
| A | ARG419-TRP426 | |
Functional Information from SwissProt/UniProt
| Chain | Residue | Details |
| A | TRP592 | |
| A | TYR593 | |
| A | GLU597 | |
| A | VAL682 | |
| A | TRP683 | |
| A | PHE696 | |
| A | TYR711 | |
| B | SER339 | |
| B | GLN483 | |
| B | TRP592 | |
| B | TYR593 | |
| B | GLU597 | |
| B | VAL682 | |
| B | TRP683 | |
| B | PHE696 | |
| B | TYR711 | |
| A | SER339 | |
| A | GLN483 | |
| Chain | Residue | Details |
| A | CYS420 | |
| B | CYS420 | |
