5AC3
Crystal structure of PAM12A
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CD A 1532 |
| Chain | Residue |
| A | ASP156 |
| A | HIS528 |
| A | ASP530 |
| A | HOH2114 |
| A | HOH2124 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CD A 1533 |
| Chain | Residue |
| A | HOH2337 |
| A | HIS445 |
| A | ACY1544 |
| A | HOH2230 |
| A | HOH2302 |
| site_id | AC3 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE CD A 1534 |
| Chain | Residue |
| A | HIS86 |
| A | ACY1545 |
| A | HOH2052 |
| A | HOH2053 |
| A | HOH2055 |
| A | HOH2338 |
| A | HOH2338 |
| site_id | AC4 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CD A 1535 |
| Chain | Residue |
| A | HIS197 |
| A | CD1536 |
| A | HOH2307 |
| site_id | AC5 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE CD A 1536 |
| Chain | Residue |
| A | HIS197 |
| A | CD1535 |
| site_id | AC6 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE CD A 1537 |
| Chain | Residue |
| A | GLU331 |
| A | GLU331 |
| site_id | AC7 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CD A 1538 |
| Chain | Residue |
| A | GLU98 |
| A | GLU101 |
| A | ACY1542 |
| A | HOH2069 |
| site_id | AC8 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CD A 1539 |
| Chain | Residue |
| A | HIS395 |
| A | HOH2261 |
| A | HOH2262 |
| A | HOH2263 |
| site_id | AC9 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE CD A 1540 |
| Chain | Residue |
| A | HIS378 |
| A | HOH2107 |
| site_id | BC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE ACY A 1541 |
| Chain | Residue |
| A | ALA415 |
| A | GLY416 |
| A | LEU417 |
| A | ALA418 |
| A | HOH2191 |
| site_id | BC2 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE ACY A 1542 |
| Chain | Residue |
| A | GLU98 |
| A | GLU101 |
| A | ARG102 |
| A | ARG155 |
| A | ASP492 |
| A | GLY493 |
| A | CD1538 |
| A | HOH2340 |
| site_id | BC3 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE ACY A 1543 |
| Chain | Residue |
| A | ASN172 |
| A | GLY201 |
| A | SER202 |
| A | ASP224 |
| A | GLY225 |
| A | SER226 |
| A | HOH2128 |
| site_id | BC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE ACY A 1544 |
| Chain | Residue |
| A | PRO346 |
| A | VAL347 |
| A | GLU348 |
| A | HIS445 |
| A | CD1533 |
| site_id | BC5 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE ACY A 1545 |
| Chain | Residue |
| A | ARG80 |
| A | HIS86 |
| A | ARG185 |
| A | GLY186 |
| A | GLY187 |
| A | CD1534 |
| A | HOH2055 |
Catalytic Information from CSA
| site_id | MCSA1 |
| Number of Residues | 3 |
| Details | M-CSA 726 |
| Chain | Residue | Details |
| A | LYS123 | electrostatic stabiliser, proton acceptor, proton donor |
| A | SER202 | electrostatic stabiliser, proton acceptor, proton donor, proton relay |
| A | SER226 | nucleofuge, nucleophile, proton acceptor, proton donor |
