5ABB
Visualization of a polytopic membrane protein during SecY-mediated membrane insertion
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005048 | molecular_function | signal sequence binding |
| A | 0005515 | molecular_function | protein binding |
| A | 0005886 | cellular_component | plasma membrane |
| A | 0006605 | biological_process | protein targeting |
| A | 0006616 | biological_process | SRP-dependent cotranslational protein targeting to membrane, translocation |
| A | 0006886 | biological_process | intracellular protein transport |
| A | 0008320 | molecular_function | protein transmembrane transporter activity |
| A | 0015031 | biological_process | protein transport |
| A | 0016020 | cellular_component | membrane |
| A | 0031522 | cellular_component | cell envelope Sec protein transport complex |
| A | 0032978 | biological_process | protein insertion into membrane from inner side |
| A | 0043952 | biological_process | protein transport by the Sec complex |
| A | 0065002 | biological_process | intracellular protein transmembrane transport |
| B | 0005886 | cellular_component | plasma membrane |
| B | 0006605 | biological_process | protein targeting |
| B | 0006886 | biological_process | intracellular protein transport |
| B | 0008320 | molecular_function | protein transmembrane transporter activity |
| B | 0009306 | biological_process | protein secretion |
| B | 0015031 | biological_process | protein transport |
| B | 0016020 | cellular_component | membrane |
| B | 0043952 | biological_process | protein transport by the Sec complex |
| B | 0065002 | biological_process | intracellular protein transmembrane transport |
| Z | 0016020 | cellular_component | membrane |
Functional Information from PROSITE/UniProt
| site_id | PS00755 |
| Number of Residues | 20 |
| Details | SECY_1 Protein secY signature 1. SIFaLGImPYIsASIIIQLL |
| Chain | Residue | Details |
| A | SER76-LEU95 |
| site_id | PS00756 |
| Number of Residues | 18 |
| Details | SECY_2 Protein secY signature 2. WLgEqITer.GIGNGiSII |
| Chain | Residue | Details |
| A | TRP173-ILE190 |
| site_id | PS01067 |
| Number of Residues | 29 |
| Details | SECE_SEC61G Protein secE/sec61-gamma signature. FaREaRteVrKviWPtrqEtlhttLIVAA |
| Chain | Residue | Details |
| B | PHE71-ALA99 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 157 |
| Details | TOPO_DOM: Cytoplasmic => ECO:0000305 |
| Chain | Residue | Details |
| A | MET1-ARG22 | |
| A | VAL97-LYS115 | |
| A | THR179-ILE183 | |
| A | GLU238-GLY273 | |
| A | PHE330-TYR380 | |
| A | MET414-ARG443 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 12 |
| Details | TRANSMEM: Helical; Name=1 => ECO:0000305 |
| Chain | Residue | Details |
| A | LEU23-ILE35 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 24 |
| Details | TOPO_DOM: Periplasmic => ECO:0000250 |
| Chain | Residue | Details |
| A | GLY36-ILE60 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 35 |
| Details | TRANSMEM: Discontinuously helical; Name=2 => ECO:0000250 |
| Chain | Residue | Details |
| A | ILE61-THR96 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 9 |
| Details | INTRAMEM: Helical; Name=Helix 2A => ECO:0000305 |
| Chain | Residue | Details |
| A | ILE61-GLY70 |
| site_id | SWS_FT_FI6 |
| Number of Residues | 5 |
| Details | INTRAMEM: INTRAMEM => ECO:0000305 |
| Chain | Residue | Details |
| A | ALA71-SER76 |
| site_id | SWS_FT_FI7 |
| Number of Residues | 19 |
| Details | INTRAMEM: Helical; Name=Helix 2B => ECO:0000305 |
| Chain | Residue | Details |
| A | ILE77-THR96 |
| site_id | SWS_FT_FI8 |
| Number of Residues | 15 |
| Details | TRANSMEM: Helical; Name=3 => ECO:0000305 |
| Chain | Residue | Details |
| A | ILE116-GLN131 |
| site_id | SWS_FT_FI9 |
| Number of Residues | 80 |
| Details | TOPO_DOM: Periplasmic => ECO:0000305 |
| Chain | Residue | Details |
| A | SER132-LEU164 | |
| A | PRO201-VAL223 | |
| A | ALA288-GLY313 | |
| A | LYS396 |
| site_id | SWS_FT_FI10 |
| Number of Residues | 13 |
| Details | TRANSMEM: Helical; Name=4 => ECO:0000305 |
| Chain | Residue | Details |
| A | VAL165-ILE178 |
| site_id | SWS_FT_FI11 |
| Number of Residues | 16 |
| Details | TRANSMEM: Helical; Name=5 => ECO:0000305 |
| Chain | Residue | Details |
| A | GLY184-PRO200 |
| site_id | SWS_FT_FI12 |
| Number of Residues | 13 |
| Details | TRANSMEM: Helical; Name=6 => ECO:0000305 |
| Chain | Residue | Details |
| A | ALA224-VAL237 |
| site_id | SWS_FT_FI13 |
| Number of Residues | 13 |
| Details | TRANSMEM: Helical; Name=7 => ECO:0000305 |
| Chain | Residue | Details |
| A | VAL274-PRO287 |
| site_id | SWS_FT_FI14 |
| Number of Residues | 15 |
| Details | TRANSMEM: Helical; Name=8 => ECO:0000305 |
| Chain | Residue | Details |
| A | GLN314-CYS329 |
| site_id | SWS_FT_FI15 |
| Number of Residues | 14 |
| Details | TRANSMEM: Helical; Name=9 => ECO:0000305 |
| Chain | Residue | Details |
| A | ILE381-MET395 |
| site_id | SWS_FT_FI16 |
| Number of Residues | 16 |
| Details | TRANSMEM: Helical; Name=10 => ECO:0000305 |
| Chain | Residue | Details |
| A | VAL397-ILE413 |
