Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

5A9Q

Human nuclear pore complex

Functional Information from GO Data

Chain	GOid	namespace	contents
0	0000776	cellular_component	kinetochore
0	0005515	molecular_function	protein binding
0	0005635	cellular_component	nuclear envelope
0	0005643	cellular_component	nuclear pore
0	0005654	cellular_component	nucleoplasm
0	0005829	cellular_component	cytosol
0	0006913	biological_process	nucleocytoplasmic transport
0	0007059	biological_process	chromosome segregation
0	0015031	biological_process	protein transport
0	0031080	cellular_component	nuclear pore outer ring
0	0051028	biological_process	mRNA transport
0	0051301	biological_process	cell division
1	0000776	cellular_component	kinetochore
1	0005515	molecular_function	protein binding
1	0005635	cellular_component	nuclear envelope
1	0005643	cellular_component	nuclear pore
1	0005829	cellular_component	cytosol
1	0006406	biological_process	mRNA export from nucleus
1	0006913	biological_process	nucleocytoplasmic transport
1	0015031	biological_process	protein transport
1	0017056	molecular_function	structural constituent of nuclear pore
1	0031080	cellular_component	nuclear pore outer ring
1	0051028	biological_process	mRNA transport
1	0072006	biological_process	nephron development
2	0000776	cellular_component	kinetochore
2	0005515	molecular_function	protein binding
2	0005634	cellular_component	nucleus
2	0005635	cellular_component	nuclear envelope
2	0005643	cellular_component	nuclear pore
2	0005654	cellular_component	nucleoplasm
2	0005829	cellular_component	cytosol
2	0006913	biological_process	nucleocytoplasmic transport
2	0007059	biological_process	chromosome segregation
2	0015031	biological_process	protein transport
2	0031080	cellular_component	nuclear pore outer ring
2	0051028	biological_process	mRNA transport
2	0051301	biological_process	cell division
3	0000776	cellular_component	kinetochore
3	0000972	biological_process	transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery
3	0005515	molecular_function	protein binding
3	0005635	cellular_component	nuclear envelope
3	0005643	cellular_component	nuclear pore
3	0005829	cellular_component	cytosol
3	0006406	biological_process	mRNA export from nucleus
3	0006606	biological_process	protein import into nucleus
3	0006913	biological_process	nucleocytoplasmic transport
3	0006999	biological_process	nuclear pore organization
3	0015031	biological_process	protein transport
3	0016020	cellular_component	membrane
3	0016973	biological_process	poly(A)+ mRNA export from nucleus
3	0017056	molecular_function	structural constituent of nuclear pore
3	0031080	cellular_component	nuclear pore outer ring
3	0031965	cellular_component	nuclear membrane
3	0048513	biological_process	animal organ development
3	0048731	biological_process	system development
3	0051028	biological_process	mRNA transport
3	0072006	biological_process	nephron development
4	0000776	cellular_component	kinetochore
4	0000973	biological_process	post-transcriptional tethering of RNA polymerase II gene DNA at nuclear periphery
4	0005515	molecular_function	protein binding
4	0005635	cellular_component	nuclear envelope
4	0005643	cellular_component	nuclear pore
4	0005829	cellular_component	cytosol
4	0006406	biological_process	mRNA export from nucleus
4	0006606	biological_process	protein import into nucleus
4	0006913	biological_process	nucleocytoplasmic transport
4	0008585	biological_process	female gonad development
4	0015031	biological_process	protein transport
4	0016020	cellular_component	membrane
4	0017056	molecular_function	structural constituent of nuclear pore
4	0031080	cellular_component	nuclear pore outer ring
4	0031965	cellular_component	nuclear membrane
4	0034399	cellular_component	nuclear periphery
4	0051028	biological_process	mRNA transport
4	0051292	biological_process	nuclear pore complex assembly
4	0072006	biological_process	nephron development
6	0000776	cellular_component	kinetochore
6	0005198	molecular_function	structural molecule activity
6	0005515	molecular_function	protein binding
6	0005635	cellular_component	nuclear envelope
6	0005643	cellular_component	nuclear pore
6	0005654	cellular_component	nucleoplasm
6	0005765	cellular_component	lysosomal membrane
6	0005783	cellular_component	endoplasmic reticulum
6	0005789	cellular_component	endoplasmic reticulum membrane
6	0005829	cellular_component	cytosol
6	0006606	biological_process	protein import into nucleus
6	0006886	biological_process	intracellular protein transport
6	0006913	biological_process	nucleocytoplasmic transport
6	0012507	cellular_component	ER to Golgi transport vesicle membrane
6	0015031	biological_process	protein transport
6	0016192	biological_process	vesicle-mediated transport
6	0030127	cellular_component	COPII vesicle coat
6	0031080	cellular_component	nuclear pore outer ring
6	0031410	cellular_component	cytoplasmic vesicle
6	0031669	biological_process	cellular response to nutrient levels
6	0032008	biological_process	positive regulation of TOR signaling
6	0032527	biological_process	protein exit from endoplasmic reticulum
6	0042802	molecular_function	identical protein binding
6	0051028	biological_process	mRNA transport
6	0061700	cellular_component	GATOR2 complex
6	0070062	cellular_component	extracellular exosome
6	0070863	biological_process	positive regulation of protein exit from endoplasmic reticulum
6	0090110	biological_process	COPII-coated vesicle cargo loading
6	0090114	biological_process	COPII-coated vesicle budding
6	1902953	biological_process	positive regulation of ER to Golgi vesicle-mediated transport
6	1904262	biological_process	negative regulation of TORC1 signaling
6	1904263	biological_process	positive regulation of TORC1 signaling
7	0000776	cellular_component	kinetochore
7	0005198	molecular_function	structural molecule activity
7	0005515	molecular_function	protein binding
7	0005635	cellular_component	nuclear envelope
7	0005643	cellular_component	nuclear pore
7	0005765	cellular_component	lysosomal membrane
7	0005829	cellular_component	cytosol
7	0006913	biological_process	nucleocytoplasmic transport
7	0006999	biological_process	nuclear pore organization
7	0007059	biological_process	chromosome segregation
7	0007080	biological_process	mitotic metaphase chromosome alignment
7	0015031	biological_process	protein transport
7	0031080	cellular_component	nuclear pore outer ring
7	0031503	biological_process	protein-containing complex localization
7	0031669	biological_process	cellular response to nutrient levels
7	0034198	biological_process	cellular response to amino acid starvation
7	0035859	cellular_component	Seh1-associated complex
7	0051028	biological_process	mRNA transport
7	0051301	biological_process	cell division
7	0051315	biological_process	attachment of mitotic spindle microtubules to kinetochore
7	0061700	cellular_component	GATOR2 complex
7	1904262	biological_process	negative regulation of TORC1 signaling
7	1904263	biological_process	positive regulation of TORC1 signaling
8	0000776	cellular_component	kinetochore
8	0005515	molecular_function	protein binding
8	0005635	cellular_component	nuclear envelope
8	0005643	cellular_component	nuclear pore
8	0005654	cellular_component	nucleoplasm
8	0005737	cellular_component	cytoplasm
8	0005819	cellular_component	spindle
8	0005829	cellular_component	cytosol
8	0006406	biological_process	mRNA export from nucleus
8	0006606	biological_process	protein import into nucleus
8	0006913	biological_process	nucleocytoplasmic transport
8	0015031	biological_process	protein transport
8	0016020	cellular_component	membrane
8	0017056	molecular_function	structural constituent of nuclear pore
8	0031080	cellular_component	nuclear pore outer ring
8	0031965	cellular_component	nuclear membrane
8	0045893	biological_process	positive regulation of DNA-templated transcription
8	0051028	biological_process	mRNA transport
8	0072006	biological_process	nephron development
9	0000776	cellular_component	kinetochore
9	0005515	molecular_function	protein binding
9	0005635	cellular_component	nuclear envelope
9	0005643	cellular_component	nuclear pore
9	0005654	cellular_component	nucleoplasm
9	0005829	cellular_component	cytosol
9	0006913	biological_process	nucleocytoplasmic transport
9	0007059	biological_process	chromosome segregation
9	0015031	biological_process	protein transport
9	0031080	cellular_component	nuclear pore outer ring
9	0051028	biological_process	mRNA transport
9	0051301	biological_process	cell division
a	0000776	cellular_component	kinetochore
a	0005515	molecular_function	protein binding
a	0005635	cellular_component	nuclear envelope
a	0005643	cellular_component	nuclear pore
a	0005829	cellular_component	cytosol
a	0006406	biological_process	mRNA export from nucleus
a	0006913	biological_process	nucleocytoplasmic transport
a	0015031	biological_process	protein transport
a	0017056	molecular_function	structural constituent of nuclear pore
a	0031080	cellular_component	nuclear pore outer ring
a	0051028	biological_process	mRNA transport
a	0072006	biological_process	nephron development
A	0000972	biological_process	transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery
A	0005515	molecular_function	protein binding
A	0005635	cellular_component	nuclear envelope
A	0005643	cellular_component	nuclear pore
A	0005829	cellular_component	cytosol
A	0006405	biological_process	RNA export from nucleus
A	0006606	biological_process	protein import into nucleus
A	0006913	biological_process	nucleocytoplasmic transport
A	0006998	biological_process	nuclear envelope organization
A	0015031	biological_process	protein transport
A	0016020	cellular_component	membrane
A	0017056	molecular_function	structural constituent of nuclear pore
A	0031965	cellular_component	nuclear membrane
A	0036228	biological_process	protein localization to nuclear inner membrane
A	0044611	cellular_component	nuclear pore inner ring
A	0051028	biological_process	mRNA transport
b	0000776	cellular_component	kinetochore
b	0005515	molecular_function	protein binding
b	0005634	cellular_component	nucleus
b	0005635	cellular_component	nuclear envelope
b	0005643	cellular_component	nuclear pore
b	0005654	cellular_component	nucleoplasm
b	0005829	cellular_component	cytosol
b	0006913	biological_process	nucleocytoplasmic transport
b	0007059	biological_process	chromosome segregation
b	0015031	biological_process	protein transport
b	0031080	cellular_component	nuclear pore outer ring
b	0051028	biological_process	mRNA transport
b	0051301	biological_process	cell division
B	0000972	biological_process	transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery
B	0005515	molecular_function	protein binding
B	0005635	cellular_component	nuclear envelope
B	0005643	cellular_component	nuclear pore
B	0005829	cellular_component	cytosol
B	0006405	biological_process	RNA export from nucleus
B	0006606	biological_process	protein import into nucleus
B	0006913	biological_process	nucleocytoplasmic transport
B	0006998	biological_process	nuclear envelope organization
B	0015031	biological_process	protein transport
B	0016020	cellular_component	membrane
B	0017056	molecular_function	structural constituent of nuclear pore
B	0031965	cellular_component	nuclear membrane
B	0036228	biological_process	protein localization to nuclear inner membrane
B	0044611	cellular_component	nuclear pore inner ring
B	0051028	biological_process	mRNA transport
C	0000776	cellular_component	kinetochore
C	0000972	biological_process	transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery
C	0005515	molecular_function	protein binding
C	0005635	cellular_component	nuclear envelope
C	0005643	cellular_component	nuclear pore
C	0005829	cellular_component	cytosol
C	0006406	biological_process	mRNA export from nucleus
C	0006606	biological_process	protein import into nucleus
C	0006913	biological_process	nucleocytoplasmic transport
C	0006999	biological_process	nuclear pore organization
C	0015031	biological_process	protein transport
C	0016020	cellular_component	membrane
C	0016973	biological_process	poly(A)+ mRNA export from nucleus
C	0017056	molecular_function	structural constituent of nuclear pore
C	0031080	cellular_component	nuclear pore outer ring
C	0031965	cellular_component	nuclear membrane
C	0048513	biological_process	animal organ development
C	0048731	biological_process	system development
C	0051028	biological_process	mRNA transport
C	0072006	biological_process	nephron development
D	0000776	cellular_component	kinetochore
D	0000973	biological_process	post-transcriptional tethering of RNA polymerase II gene DNA at nuclear periphery
D	0005515	molecular_function	protein binding
D	0005635	cellular_component	nuclear envelope
D	0005643	cellular_component	nuclear pore
D	0005829	cellular_component	cytosol
D	0006406	biological_process	mRNA export from nucleus
D	0006606	biological_process	protein import into nucleus
D	0006913	biological_process	nucleocytoplasmic transport
D	0008585	biological_process	female gonad development
D	0015031	biological_process	protein transport
D	0016020	cellular_component	membrane
D	0017056	molecular_function	structural constituent of nuclear pore
D	0031080	cellular_component	nuclear pore outer ring
D	0031965	cellular_component	nuclear membrane
D	0034399	cellular_component	nuclear periphery
D	0051028	biological_process	mRNA transport
D	0051292	biological_process	nuclear pore complex assembly
D	0072006	biological_process	nephron development
F	0000776	cellular_component	kinetochore
F	0005198	molecular_function	structural molecule activity
F	0005515	molecular_function	protein binding
F	0005635	cellular_component	nuclear envelope
F	0005643	cellular_component	nuclear pore
F	0005654	cellular_component	nucleoplasm
F	0005765	cellular_component	lysosomal membrane
F	0005783	cellular_component	endoplasmic reticulum
F	0005789	cellular_component	endoplasmic reticulum membrane
F	0005829	cellular_component	cytosol
F	0006606	biological_process	protein import into nucleus
F	0006886	biological_process	intracellular protein transport
F	0006913	biological_process	nucleocytoplasmic transport
F	0012507	cellular_component	ER to Golgi transport vesicle membrane
F	0015031	biological_process	protein transport
F	0016192	biological_process	vesicle-mediated transport
F	0030127	cellular_component	COPII vesicle coat
F	0031080	cellular_component	nuclear pore outer ring
F	0031410	cellular_component	cytoplasmic vesicle
F	0031669	biological_process	cellular response to nutrient levels
F	0032008	biological_process	positive regulation of TOR signaling
F	0032527	biological_process	protein exit from endoplasmic reticulum
F	0042802	molecular_function	identical protein binding
F	0051028	biological_process	mRNA transport
F	0061700	cellular_component	GATOR2 complex
F	0070062	cellular_component	extracellular exosome
F	0070863	biological_process	positive regulation of protein exit from endoplasmic reticulum
F	0090110	biological_process	COPII-coated vesicle cargo loading
F	0090114	biological_process	COPII-coated vesicle budding
F	1902953	biological_process	positive regulation of ER to Golgi vesicle-mediated transport
F	1904262	biological_process	negative regulation of TORC1 signaling
F	1904263	biological_process	positive regulation of TORC1 signaling
G	0000776	cellular_component	kinetochore
G	0005198	molecular_function	structural molecule activity
G	0005515	molecular_function	protein binding
G	0005635	cellular_component	nuclear envelope
G	0005643	cellular_component	nuclear pore
G	0005765	cellular_component	lysosomal membrane
G	0005829	cellular_component	cytosol
G	0006913	biological_process	nucleocytoplasmic transport
G	0006999	biological_process	nuclear pore organization
G	0007059	biological_process	chromosome segregation
G	0007080	biological_process	mitotic metaphase chromosome alignment
G	0015031	biological_process	protein transport
G	0031080	cellular_component	nuclear pore outer ring
G	0031503	biological_process	protein-containing complex localization
G	0031669	biological_process	cellular response to nutrient levels
G	0034198	biological_process	cellular response to amino acid starvation
G	0035859	cellular_component	Seh1-associated complex
G	0051028	biological_process	mRNA transport
G	0051301	biological_process	cell division
G	0051315	biological_process	attachment of mitotic spindle microtubules to kinetochore
G	0061700	cellular_component	GATOR2 complex
G	1904262	biological_process	negative regulation of TORC1 signaling
G	1904263	biological_process	positive regulation of TORC1 signaling
H	0000776	cellular_component	kinetochore
H	0005515	molecular_function	protein binding
H	0005635	cellular_component	nuclear envelope
H	0005643	cellular_component	nuclear pore
H	0005654	cellular_component	nucleoplasm
H	0005737	cellular_component	cytoplasm
H	0005819	cellular_component	spindle
H	0005829	cellular_component	cytosol
H	0006406	biological_process	mRNA export from nucleus
H	0006606	biological_process	protein import into nucleus
H	0006913	biological_process	nucleocytoplasmic transport
H	0015031	biological_process	protein transport
H	0016020	cellular_component	membrane
H	0017056	molecular_function	structural constituent of nuclear pore
H	0031080	cellular_component	nuclear pore outer ring
H	0031965	cellular_component	nuclear membrane
H	0045893	biological_process	positive regulation of DNA-templated transcription
H	0051028	biological_process	mRNA transport
H	0072006	biological_process	nephron development
I	0000776	cellular_component	kinetochore
I	0005515	molecular_function	protein binding
I	0005635	cellular_component	nuclear envelope
I	0005643	cellular_component	nuclear pore
I	0005654	cellular_component	nucleoplasm
I	0005829	cellular_component	cytosol
I	0006913	biological_process	nucleocytoplasmic transport
I	0007059	biological_process	chromosome segregation
I	0015031	biological_process	protein transport
I	0031080	cellular_component	nuclear pore outer ring
I	0051028	biological_process	mRNA transport
I	0051301	biological_process	cell division
J	0000776	cellular_component	kinetochore
J	0005515	molecular_function	protein binding
J	0005635	cellular_component	nuclear envelope
J	0005643	cellular_component	nuclear pore
J	0005829	cellular_component	cytosol
J	0006406	biological_process	mRNA export from nucleus
J	0006913	biological_process	nucleocytoplasmic transport
J	0015031	biological_process	protein transport
J	0017056	molecular_function	structural constituent of nuclear pore
J	0031080	cellular_component	nuclear pore outer ring
J	0051028	biological_process	mRNA transport
J	0072006	biological_process	nephron development
K	0000776	cellular_component	kinetochore
K	0005515	molecular_function	protein binding
K	0005634	cellular_component	nucleus
K	0005635	cellular_component	nuclear envelope
K	0005643	cellular_component	nuclear pore
K	0005654	cellular_component	nucleoplasm
K	0005829	cellular_component	cytosol
K	0006913	biological_process	nucleocytoplasmic transport
K	0007059	biological_process	chromosome segregation
K	0015031	biological_process	protein transport
K	0031080	cellular_component	nuclear pore outer ring
K	0051028	biological_process	mRNA transport
K	0051301	biological_process	cell division
L	0000776	cellular_component	kinetochore
L	0000972	biological_process	transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery
L	0005515	molecular_function	protein binding
L	0005635	cellular_component	nuclear envelope
L	0005643	cellular_component	nuclear pore
L	0005829	cellular_component	cytosol
L	0006406	biological_process	mRNA export from nucleus
L	0006606	biological_process	protein import into nucleus
L	0006913	biological_process	nucleocytoplasmic transport
L	0006999	biological_process	nuclear pore organization
L	0015031	biological_process	protein transport
L	0016020	cellular_component	membrane
L	0016973	biological_process	poly(A)+ mRNA export from nucleus
L	0017056	molecular_function	structural constituent of nuclear pore
L	0031080	cellular_component	nuclear pore outer ring
L	0031965	cellular_component	nuclear membrane
L	0048513	biological_process	animal organ development
L	0048731	biological_process	system development
L	0051028	biological_process	mRNA transport
L	0072006	biological_process	nephron development
M	0000776	cellular_component	kinetochore
M	0000973	biological_process	post-transcriptional tethering of RNA polymerase II gene DNA at nuclear periphery
M	0005515	molecular_function	protein binding
M	0005635	cellular_component	nuclear envelope
M	0005643	cellular_component	nuclear pore
M	0005829	cellular_component	cytosol
M	0006406	biological_process	mRNA export from nucleus
M	0006606	biological_process	protein import into nucleus
M	0006913	biological_process	nucleocytoplasmic transport
M	0008585	biological_process	female gonad development
M	0015031	biological_process	protein transport
M	0016020	cellular_component	membrane
M	0017056	molecular_function	structural constituent of nuclear pore
M	0031080	cellular_component	nuclear pore outer ring
M	0031965	cellular_component	nuclear membrane
M	0034399	cellular_component	nuclear periphery
M	0051028	biological_process	mRNA transport
M	0051292	biological_process	nuclear pore complex assembly
M	0072006	biological_process	nephron development
O	0000776	cellular_component	kinetochore
O	0005198	molecular_function	structural molecule activity
O	0005515	molecular_function	protein binding
O	0005635	cellular_component	nuclear envelope
O	0005643	cellular_component	nuclear pore
O	0005654	cellular_component	nucleoplasm
O	0005765	cellular_component	lysosomal membrane
O	0005783	cellular_component	endoplasmic reticulum
O	0005789	cellular_component	endoplasmic reticulum membrane
O	0005829	cellular_component	cytosol
O	0006606	biological_process	protein import into nucleus
O	0006886	biological_process	intracellular protein transport
O	0006913	biological_process	nucleocytoplasmic transport
O	0012507	cellular_component	ER to Golgi transport vesicle membrane
O	0015031	biological_process	protein transport
O	0016192	biological_process	vesicle-mediated transport
O	0030127	cellular_component	COPII vesicle coat
O	0031080	cellular_component	nuclear pore outer ring
O	0031410	cellular_component	cytoplasmic vesicle
O	0031669	biological_process	cellular response to nutrient levels
O	0032008	biological_process	positive regulation of TOR signaling
O	0032527	biological_process	protein exit from endoplasmic reticulum
O	0042802	molecular_function	identical protein binding
O	0051028	biological_process	mRNA transport
O	0061700	cellular_component	GATOR2 complex
O	0070062	cellular_component	extracellular exosome
O	0070863	biological_process	positive regulation of protein exit from endoplasmic reticulum
O	0090110	biological_process	COPII-coated vesicle cargo loading
O	0090114	biological_process	COPII-coated vesicle budding
O	1902953	biological_process	positive regulation of ER to Golgi vesicle-mediated transport
O	1904262	biological_process	negative regulation of TORC1 signaling
O	1904263	biological_process	positive regulation of TORC1 signaling
P	0000776	cellular_component	kinetochore
P	0005198	molecular_function	structural molecule activity
P	0005515	molecular_function	protein binding
P	0005635	cellular_component	nuclear envelope
P	0005643	cellular_component	nuclear pore
P	0005765	cellular_component	lysosomal membrane
P	0005829	cellular_component	cytosol
P	0006913	biological_process	nucleocytoplasmic transport
P	0006999	biological_process	nuclear pore organization
P	0007059	biological_process	chromosome segregation
P	0007080	biological_process	mitotic metaphase chromosome alignment
P	0015031	biological_process	protein transport
P	0031080	cellular_component	nuclear pore outer ring
P	0031503	biological_process	protein-containing complex localization
P	0031669	biological_process	cellular response to nutrient levels
P	0034198	biological_process	cellular response to amino acid starvation
P	0035859	cellular_component	Seh1-associated complex
P	0051028	biological_process	mRNA transport
P	0051301	biological_process	cell division
P	0051315	biological_process	attachment of mitotic spindle microtubules to kinetochore
P	0061700	cellular_component	GATOR2 complex
P	1904262	biological_process	negative regulation of TORC1 signaling
P	1904263	biological_process	positive regulation of TORC1 signaling
Q	0000776	cellular_component	kinetochore
Q	0005515	molecular_function	protein binding
Q	0005635	cellular_component	nuclear envelope
Q	0005643	cellular_component	nuclear pore
Q	0005654	cellular_component	nucleoplasm
Q	0005737	cellular_component	cytoplasm
Q	0005819	cellular_component	spindle
Q	0005829	cellular_component	cytosol
Q	0006406	biological_process	mRNA export from nucleus
Q	0006606	biological_process	protein import into nucleus
Q	0006913	biological_process	nucleocytoplasmic transport
Q	0015031	biological_process	protein transport
Q	0016020	cellular_component	membrane
Q	0017056	molecular_function	structural constituent of nuclear pore
Q	0031080	cellular_component	nuclear pore outer ring
Q	0031965	cellular_component	nuclear membrane
Q	0045893	biological_process	positive regulation of DNA-templated transcription
Q	0051028	biological_process	mRNA transport
Q	0072006	biological_process	nephron development
R	0000776	cellular_component	kinetochore
R	0005515	molecular_function	protein binding
R	0005635	cellular_component	nuclear envelope
R	0005643	cellular_component	nuclear pore
R	0005654	cellular_component	nucleoplasm
R	0005829	cellular_component	cytosol
R	0006913	biological_process	nucleocytoplasmic transport
R	0007059	biological_process	chromosome segregation
R	0015031	biological_process	protein transport
R	0031080	cellular_component	nuclear pore outer ring
R	0051028	biological_process	mRNA transport
R	0051301	biological_process	cell division
S	0000776	cellular_component	kinetochore
S	0005515	molecular_function	protein binding
S	0005635	cellular_component	nuclear envelope
S	0005643	cellular_component	nuclear pore
S	0005829	cellular_component	cytosol
S	0006406	biological_process	mRNA export from nucleus
S	0006913	biological_process	nucleocytoplasmic transport
S	0015031	biological_process	protein transport
S	0017056	molecular_function	structural constituent of nuclear pore
S	0031080	cellular_component	nuclear pore outer ring
S	0051028	biological_process	mRNA transport
S	0072006	biological_process	nephron development
T	0000776	cellular_component	kinetochore
T	0005515	molecular_function	protein binding
T	0005634	cellular_component	nucleus
T	0005635	cellular_component	nuclear envelope
T	0005643	cellular_component	nuclear pore
T	0005654	cellular_component	nucleoplasm
T	0005829	cellular_component	cytosol
T	0006913	biological_process	nucleocytoplasmic transport
T	0007059	biological_process	chromosome segregation
T	0015031	biological_process	protein transport
T	0031080	cellular_component	nuclear pore outer ring
T	0051028	biological_process	mRNA transport
T	0051301	biological_process	cell division
U	0000776	cellular_component	kinetochore
U	0000972	biological_process	transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery
U	0005515	molecular_function	protein binding
U	0005635	cellular_component	nuclear envelope
U	0005643	cellular_component	nuclear pore
U	0005829	cellular_component	cytosol
U	0006406	biological_process	mRNA export from nucleus
U	0006606	biological_process	protein import into nucleus
U	0006913	biological_process	nucleocytoplasmic transport
U	0006999	biological_process	nuclear pore organization
U	0015031	biological_process	protein transport
U	0016020	cellular_component	membrane
U	0016973	biological_process	poly(A)+ mRNA export from nucleus
U	0017056	molecular_function	structural constituent of nuclear pore
U	0031080	cellular_component	nuclear pore outer ring
U	0031965	cellular_component	nuclear membrane
U	0048513	biological_process	animal organ development
U	0048731	biological_process	system development
U	0051028	biological_process	mRNA transport
U	0072006	biological_process	nephron development
V	0000776	cellular_component	kinetochore
V	0000973	biological_process	post-transcriptional tethering of RNA polymerase II gene DNA at nuclear periphery
V	0005515	molecular_function	protein binding
V	0005635	cellular_component	nuclear envelope
V	0005643	cellular_component	nuclear pore
V	0005829	cellular_component	cytosol
V	0006406	biological_process	mRNA export from nucleus
V	0006606	biological_process	protein import into nucleus
V	0006913	biological_process	nucleocytoplasmic transport
V	0008585	biological_process	female gonad development
V	0015031	biological_process	protein transport
V	0016020	cellular_component	membrane
V	0017056	molecular_function	structural constituent of nuclear pore
V	0031080	cellular_component	nuclear pore outer ring
V	0031965	cellular_component	nuclear membrane
V	0034399	cellular_component	nuclear periphery
V	0051028	biological_process	mRNA transport
V	0051292	biological_process	nuclear pore complex assembly
V	0072006	biological_process	nephron development
X	0000776	cellular_component	kinetochore
X	0005198	molecular_function	structural molecule activity
X	0005515	molecular_function	protein binding
X	0005635	cellular_component	nuclear envelope
X	0005643	cellular_component	nuclear pore
X	0005654	cellular_component	nucleoplasm
X	0005765	cellular_component	lysosomal membrane
X	0005783	cellular_component	endoplasmic reticulum
X	0005789	cellular_component	endoplasmic reticulum membrane
X	0005829	cellular_component	cytosol
X	0006606	biological_process	protein import into nucleus
X	0006886	biological_process	intracellular protein transport
X	0006913	biological_process	nucleocytoplasmic transport
X	0012507	cellular_component	ER to Golgi transport vesicle membrane
X	0015031	biological_process	protein transport
X	0016192	biological_process	vesicle-mediated transport
X	0030127	cellular_component	COPII vesicle coat
X	0031080	cellular_component	nuclear pore outer ring
X	0031410	cellular_component	cytoplasmic vesicle
X	0031669	biological_process	cellular response to nutrient levels
X	0032008	biological_process	positive regulation of TOR signaling
X	0032527	biological_process	protein exit from endoplasmic reticulum
X	0042802	molecular_function	identical protein binding
X	0051028	biological_process	mRNA transport
X	0061700	cellular_component	GATOR2 complex
X	0070062	cellular_component	extracellular exosome
X	0070863	biological_process	positive regulation of protein exit from endoplasmic reticulum
X	0090110	biological_process	COPII-coated vesicle cargo loading
X	0090114	biological_process	COPII-coated vesicle budding
X	1902953	biological_process	positive regulation of ER to Golgi vesicle-mediated transport
X	1904262	biological_process	negative regulation of TORC1 signaling
X	1904263	biological_process	positive regulation of TORC1 signaling
Y	0000776	cellular_component	kinetochore
Y	0005198	molecular_function	structural molecule activity
Y	0005515	molecular_function	protein binding
Y	0005635	cellular_component	nuclear envelope
Y	0005643	cellular_component	nuclear pore
Y	0005765	cellular_component	lysosomal membrane
Y	0005829	cellular_component	cytosol
Y	0006913	biological_process	nucleocytoplasmic transport
Y	0006999	biological_process	nuclear pore organization
Y	0007059	biological_process	chromosome segregation
Y	0007080	biological_process	mitotic metaphase chromosome alignment
Y	0015031	biological_process	protein transport
Y	0031080	cellular_component	nuclear pore outer ring
Y	0031503	biological_process	protein-containing complex localization
Y	0031669	biological_process	cellular response to nutrient levels
Y	0034198	biological_process	cellular response to amino acid starvation
Y	0035859	cellular_component	Seh1-associated complex
Y	0051028	biological_process	mRNA transport
Y	0051301	biological_process	cell division
Y	0051315	biological_process	attachment of mitotic spindle microtubules to kinetochore
Y	0061700	cellular_component	GATOR2 complex
Y	1904262	biological_process	negative regulation of TORC1 signaling
Y	1904263	biological_process	positive regulation of TORC1 signaling
Z	0000776	cellular_component	kinetochore
Z	0005515	molecular_function	protein binding
Z	0005635	cellular_component	nuclear envelope
Z	0005643	cellular_component	nuclear pore
Z	0005654	cellular_component	nucleoplasm
Z	0005737	cellular_component	cytoplasm
Z	0005819	cellular_component	spindle
Z	0005829	cellular_component	cytosol
Z	0006406	biological_process	mRNA export from nucleus
Z	0006606	biological_process	protein import into nucleus
Z	0006913	biological_process	nucleocytoplasmic transport
Z	0015031	biological_process	protein transport
Z	0016020	cellular_component	membrane
Z	0017056	molecular_function	structural constituent of nuclear pore
Z	0031080	cellular_component	nuclear pore outer ring
Z	0031965	cellular_component	nuclear membrane
Z	0045893	biological_process	positive regulation of DNA-templated transcription
Z	0051028	biological_process	mRNA transport
Z	0072006	biological_process	nephron development

Functional Information from PROSITE/UniProt

site_id	PS00616
Number of Residues	15
Details	HIS_ACID_PHOSPHAT_1 Histidine acid phosphatases phosphohistidine signature. LlyAfhIyRHNyRkA

Chain	Residue	Details
1	LEU1083-ALA1097

site_id	PS00678
Number of Residues	15
Details	WD_REPEATS_1 Trp-Asp (WD) repeats signature. VATGgqDgMLSIWDV

Chain	Residue	Details
0	VAL233-VAL247
2	ILE140-LEU154

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	672
Details	Repeat: {"description":"WD 2"}

Chain

Residue

Details

site_id	SWS_FT_FI2
Number of Residues	496
Details	Repeat: {"description":"WD 4"}

Chain

Residue

Details

site_id	SWS_FT_FI3
Number of Residues	648
Details	Repeat: {"description":"WD 5"}

Chain

Residue

Details

site_id	SWS_FT_FI4
Number of Residues	26
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI5
Number of Residues	492
Details	Repeat: {"description":"WD 3"}

Chain

Residue

Details

site_id	SWS_FT_FI6
Number of Residues	472
Details	Repeat: {"description":"WD 6"}

Chain

Residue

Details

site_id	SWS_FT_FI7
Number of Residues	148
Details	Repeat: {"description":"WD 7"}

Chain

Residue

Details

site_id	SWS_FT_FI8
Number of Residues	4
Details	Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"UniProtKB","id":"Q8R0G9","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

site_id	SWS_FT_FI9
Number of Residues	4
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"UniProtKB","id":"Q6PFD9","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

site_id	SWS_FT_FI10
Number of Residues	156
Details	Repeat: {"description":"WD 1"}

Chain

Residue

Details

site_id	SWS_FT_FI11
Number of Residues	8
Details	Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)","evidences":[{"source":"PubMed","id":"28112733","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI12
Number of Residues	4
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"18691976","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)