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5A5R

Crystal structure of human ATAD2 bromodomain in complex with 5-5- methoxypyridin-3-yl-3-methyl-8-piperidin-4-ylamino-1,2-dihydro-1,7- naphthyridin-2-one

Functional Information from GO Data
ChainGOidnamespacecontents
A0006325biological_processchromatin organization
A0006355biological_processregulation of transcription, DNA-templated
A0016887molecular_functionATP hydrolysis activity
Functional Information from PDB Data
site_idAC1
Number of Residues5
DetailsBINDING SITE FOR RESIDUE EDO A 2109
ChainResidue
AGLU988
ALEU1093
AASP1094
APHE1097
AHOH3186

site_idAC2
Number of Residues6
DetailsBINDING SITE FOR RESIDUE EDO A 2110
ChainResidue
AHOH3173
AHOH3187
AHIS998
AGLU1091
AHOH3166
AHOH3170

site_idAC3
Number of Residues7
DetailsBINDING SITE FOR RESIDUE NP8 A 2111
ChainResidue
AVAL1013
AASP1014
AGLU1017
AVAL1018
AASN1064
AASP1071
AHOH3091

site_idAC4
Number of Residues5
DetailsBINDING SITE FOR RESIDUE SO4 A 2112
ChainResidue
AARG1077
AHOH3177
AHOH3178
AHOH3189
AHOH3190

site_idAC5
Number of Residues7
DetailsBINDING SITE FOR RESIDUE SO4 A 2113
ChainResidue
AARG987
AARG990
AARG994
AARG1067
AARG1072
AHOH3056
AHOH3146

site_idAC6
Number of Residues5
DetailsBINDING SITE FOR RESIDUE SO4 A 2114
ChainResidue
AGLN1027
ALYS1037
ALYS1042
AHOH3110
AHOH3111

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PDB entries from 2024-11-13

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