5A5N

Crystal structure of human ATAD2 bromodomain in complex with (2S)-2,6- diacetamido-N-methylhexanamide

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0006325	biological_process	chromatin organization
A	0006355	biological_process	regulation of transcription, DNA-templated
A	0016887	molecular_function	ATP hydrolysis activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE EDO A 2109

Chain	Residue
A	HIS998
A	GLU1091
A	GLU1092
A	LEU1093
A	ASP1094

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site_id	AC2
Number of Residues	6
Details	BINDING SITE FOR RESIDUE EDO A 2110

Chain	Residue
A	HOH3207
A	HOH3208
A	GLU988
A	LEU1093
A	ASP1094
A	PHE1097

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site_id	AC3
Number of Residues	6
Details	BINDING SITE FOR RESIDUE 8WS A 2111

Chain	Residue
A	VAL1018
A	TYR1063
A	ASN1064
A	ILE1074
A	HOH3104
A	HOH3209

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site_id	AC4
Number of Residues	3
Details	BINDING SITE FOR RESIDUE SO4 A 2112

Chain	Residue
A	ARG1077
A	HOH3090
A	HOH3196

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site_id	AC5
Number of Residues	7
Details	BINDING SITE FOR RESIDUE SO4 A 2113

Chain	Residue
A	ARG987
A	ARG990
A	ARG994
A	ARG1067
A	ARG1072
A	HOH3069
A	HOH3160

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