Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0004329 | molecular_function | formate-tetrahydrofolate ligase activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0006730 | biological_process | one-carbon metabolic process |
| A | 0016874 | molecular_function | ligase activity |
| A | 0035999 | biological_process | tetrahydrofolate interconversion |
| B | 0000166 | molecular_function | nucleotide binding |
| B | 0004329 | molecular_function | formate-tetrahydrofolate ligase activity |
| B | 0005524 | molecular_function | ATP binding |
| B | 0006730 | biological_process | one-carbon metabolic process |
| B | 0016874 | molecular_function | ligase activity |
| B | 0035999 | biological_process | tetrahydrofolate interconversion |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE K A 1562 |
| Chain | Residue |
| A | GLU96 |
| A | PRO97 |
| A | ILE123 |
| A | LEU125 |
| site_id | AC2 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE GOL A 1563 |
| Chain | Residue |
| A | VAL189 |
| A | HOH2109 |
| B | ARG173 |
| B | GLN174 |
| A | ASP146 |
| A | ASN147 |
| A | PHE150 |
| A | ASN187 |
| A | GLY188 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE K A 1564 |
| Chain | Residue |
| B | VAL162 |
| B | GLU192 |
| B | HOH2112 |
| B | HOH2115 |
| B | HOH2120 |
| B | HOH2123 |
| site_id | AC4 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE PEG A 1565 |
| Chain | Residue |
| A | GLY183 |
| A | HOH2313 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE K B 1562 |
| Chain | Residue |
| B | GLU96 |
| B | PRO97 |
| B | ILE123 |
| B | ASN124 |
| B | LEU125 |
| B | HOH2069 |
| site_id | AC6 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE K B 1563 |
| Chain | Residue |
| A | VAL162 |
| A | GLU192 |
| A | HOH2045 |
| A | HOH2129 |
| A | HOH2135 |
Functional Information from PROSITE/UniProt
| site_id | PS00721 |
| Number of Residues | 11 |
| Details | FTHFS_1 Formate--tetrahydrofolate ligase signature 1. GIKGGAAGGGY |
| Chain | Residue | Details |
| A | GLY104-TYR114 | |
| site_id | PS00722 |
| Number of Residues | 12 |
| Details | FTHFS_2 Formate--tetrahydrofolate ligase signature 2. VATVRALKyNGG |
| Chain | Residue | Details |
| A | VAL329-GLY340 | |
