5A40
Crystal structure of a dual topology fluoride ion channel.
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005886 | cellular_component | plasma membrane |
| A | 0016020 | cellular_component | membrane |
| A | 0062054 | molecular_function | fluoride channel activity |
| A | 0140114 | biological_process | cellular detoxification of fluoride |
| A | 1903424 | biological_process | fluoride transmembrane transport |
| A | 1903425 | molecular_function | fluoride transmembrane transporter activity |
| B | 0005886 | cellular_component | plasma membrane |
| B | 0016020 | cellular_component | membrane |
| B | 0062054 | molecular_function | fluoride channel activity |
| B | 0140114 | biological_process | cellular detoxification of fluoride |
| B | 1903424 | biological_process | fluoride transmembrane transport |
| B | 1903425 | molecular_function | fluoride transmembrane transporter activity |
| C | 0005886 | cellular_component | plasma membrane |
| C | 0016020 | cellular_component | membrane |
| C | 0062054 | molecular_function | fluoride channel activity |
| C | 0140114 | biological_process | cellular detoxification of fluoride |
| C | 1903424 | biological_process | fluoride transmembrane transport |
| C | 1903425 | molecular_function | fluoride transmembrane transporter activity |
| D | 0005886 | cellular_component | plasma membrane |
| D | 0016020 | cellular_component | membrane |
| D | 0062054 | molecular_function | fluoride channel activity |
| D | 0140114 | biological_process | cellular detoxification of fluoride |
| D | 1903424 | biological_process | fluoride transmembrane transport |
| D | 1903425 | molecular_function | fluoride transmembrane transporter activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE HG F 1092 |
| Chain | Residue |
| B | ASP91 |
| B | CYS94 |
| F | TYR75 |
| site_id | AC2 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE HG E 1092 |
| Chain | Residue |
| A | ASP91 |
| A | CYS94 |
| E | HIS81 |
| site_id | AC3 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE HG G 1092 |
| Chain | Residue |
| C | ASP91 |
| C | CYS94 |
| G | HIS81 |
| site_id | AC4 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE HG H 1092 |
| Chain | Residue |
| D | ASP91 |
| D | CYS94 |
| H | HIS81 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 400 |
| Details | Transmembrane: {"description":"Helical","evidences":[{"source":"PubMed","id":"26344196","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5A40","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5NKQ","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 16 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"26344196","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5NKQ","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 8 |
| Details | Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_00454","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"26344196","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5NKQ","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
