5A11
The crystal structure of Ta-TFP, a thiocyanate-forming protein involved in glucosinolate breakdown (space group P21)
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005634 | cellular_component | nucleus |
| A | 0005829 | cellular_component | cytosol |
| A | 0016829 | molecular_function | lyase activity |
| A | 0019760 | biological_process | glucosinolate metabolic process |
| A | 0030234 | molecular_function | enzyme regulator activity |
| A | 0042802 | molecular_function | identical protein binding |
| A | 0042803 | molecular_function | protein homodimerization activity |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0080028 | biological_process | nitrile biosynthetic process |
| B | 0005634 | cellular_component | nucleus |
| B | 0005829 | cellular_component | cytosol |
| B | 0016829 | molecular_function | lyase activity |
| B | 0019760 | biological_process | glucosinolate metabolic process |
| B | 0030234 | molecular_function | enzyme regulator activity |
| B | 0042802 | molecular_function | identical protein binding |
| B | 0042803 | molecular_function | protein homodimerization activity |
| B | 0046872 | molecular_function | metal ion binding |
| B | 0080028 | biological_process | nitrile biosynthetic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE IOD A 1349 |
| Chain | Residue |
| A | ARG157 |
| site_id | AC2 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE IOD B 1349 |
| Chain | Residue |
| B | ARG157 |
| site_id | AC3 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE IOD B 1350 |
| Chain | Residue |
| B | ARG80 |
| site_id | AC4 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE IOD A 1350 |
| Chain | Residue |
| A | ARG80 |
| site_id | AC5 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE IOD A 1351 |
| Chain | Residue |
| A | MET10 |
| site_id | AC6 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE IOD B 1351 |
| Chain | Residue |
| B | ARG94 |
| B | LYS148 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 102 |
| Details | Repeat: {"description":"Kelch 2","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 92 |
| Details | Repeat: {"description":"Kelch 3","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 110 |
| Details | Repeat: {"description":"Kelch 4","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 90 |
| Details | Repeat: {"description":"Kelch 5","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 110 |
| Details | Repeat: {"description":"Kelch 6","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 52 |
| Details | Repeat: {"description":"Kelch 7","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI7 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Proton donor","evidences":[{"source":"PubMed","id":"26260516","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"23999604","evidenceCode":"ECO:0000305"},{"source":"PubMed","id":"28479247","evidenceCode":"ECO:0000305"},{"source":"PubMed","id":"30900313","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI8 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Proton donor","evidences":[{"source":"PubMed","id":"26260516","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"28479247","evidenceCode":"ECO:0000305"},{"source":"PubMed","id":"30900313","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI9 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Proton acceptor","evidences":[{"source":"PubMed","id":"30900313","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI10 |
| Number of Residues | 4 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"23999604","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI11 |
| Number of Residues | 8 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"23999604","evidenceCode":"ECO:0000305"},{"source":"PubMed","id":"26260516","evidenceCode":"ECO:0000305"},{"source":"PubMed","id":"28479247","evidenceCode":"ECO:0000305"},{"source":"PubMed","id":"30900313","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI12 |
| Number of Residues | 2 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"28479247","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI13 |
| Number of Residues | 2 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"23999604","evidenceCode":"ECO:0000305"},{"source":"PubMed","id":"26260516","evidenceCode":"ECO:0000305"},{"source":"PubMed","id":"30900313","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI14 |
| Number of Residues | 4 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"26260516","evidenceCode":"ECO:0000305"},{"source":"PubMed","id":"28479247","evidenceCode":"ECO:0000305"},{"source":"PubMed","id":"30900313","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI15 |
| Number of Residues | 2 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"23999604","evidenceCode":"ECO:0000305"},{"source":"PubMed","id":"28479247","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI16 |
| Number of Residues | 2 |
| Details | Site: {"description":"Essential for catalytic activity","evidences":[{"source":"PubMed","id":"30900313","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI17 |
| Number of Residues | 2 |
| Details | Site: {"description":"Critical for thiocyanate and epithionitrile formation with allylglucosinolate in the presence of myrosinase","evidences":[{"source":"PubMed","id":"30900313","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
