5A0W

THE CRYSTAL STRUCTURE OF I-DMOI E117A IN COMPLEX WITH ITS TARGET DNA AND IN THE PRESENCE OF 2MM MN

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004518	molecular_function	nuclease activity
A	0004519	molecular_function	endonuclease activity
A	0006314	biological_process	intron homing
A	0016539	biological_process	intein-mediated protein splicing
A	0016787	molecular_function	hydrolase activity
D	0004518	molecular_function	nuclease activity
D	0004519	molecular_function	endonuclease activity
D	0006314	biological_process	intron homing
D	0016539	biological_process	intein-mediated protein splicing
D	0016787	molecular_function	hydrolase activity
G	0004518	molecular_function	nuclease activity
G	0004519	molecular_function	endonuclease activity
G	0006314	biological_process	intron homing
G	0016539	biological_process	intein-mediated protein splicing
G	0016787	molecular_function	hydrolase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	1
Details	BINDING SITE FOR RESIDUE CL A 1187

Chain	Residue
A	LYS66

---

site_id	AC2
Number of Residues	3
Details	BINDING SITE FOR RESIDUE ACT A 1188

Chain	Residue
A	LYS111
A	LEU182
A	ASN183

---

site_id	AC3
Number of Residues	1
Details	BINDING SITE FOR RESIDUE CL A 1300

Chain	Residue
A	HOH2009

---

site_id	AC4
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ACT C 1026

Chain	Residue
A	ALA117
A	HOH2007
C	DC15
C	DC16

---

site_id	AC5
Number of Residues	3
Details	BINDING SITE FOR RESIDUE ACT C 1027

Chain	Residue
B	DG23
C	DG4
C	DC5

---

site_id	AC6
Number of Residues	2
Details	BINDING SITE FOR RESIDUE CL D 1196

Chain	Residue
D	TYR114
D	HOH2073

---

site_id	AC7
Number of Residues	2
Details	BINDING SITE FOR RESIDUE CL F 1026

Chain	Residue
F	DG4
F	DC5

---

site_id	AC8
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ACT F 1027

Chain	Residue
D	HOH2005
E	DG15
F	DC15
F	DC16

---

site_id	AC9
Number of Residues	1
Details	BINDING SITE FOR RESIDUE CL H 1026

Chain	Residue
H	DG6

---

site_id	BC1
Number of Residues	7
Details	BINDING SITE FOR RESIDUE ACT I 1026

Chain	Residue
G	GLY20
G	ALA117
G	HOH2006
H	DG15
I	DC15
I	DC16
I	HOH2010

---

site_id	BC2
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MN B 1026

Chain	Residue
B	DG15
B	HOH2018
B	HOH2019
B	HOH2020
B	HOH2043
C	DC15

---

site_id	BC3
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MN A 1189

Chain	Residue
A	ASP21
A	ALA116
A	HOH2008
B	DA14
C	DC16

---

site_id	BC4
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MN D 1197

Chain	Residue
D	ASP21
D	ALA116
D	HOH2007
E	DA14
F	DC16

---

site_id	BC5
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MN F 1028

Chain	Residue
E	DG15
E	HOH2006
E	HOH2007
E	HOH2008
F	DC15
F	HOH2006

---

site_id	BC6
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MN G 1183

Chain	Residue
G	ASP21
G	ALA116
G	HOH2007
H	DA14
I	DC16

---

site_id	BC7
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MN H 1027

Chain	Residue
H	DG15
H	HOH2008
H	HOH2009
H	HOH2010
H	HOH2019
I	DC15

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	399
Details	Domain: {"description":"DOD-type homing endonuclease","evidences":[{"source":"PROSITE-ProRule","id":"PRU00273","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	6
Details	Active site: {}

Chain

Residue

Details

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