4ZYQ
X-ray crystal structure of PfA-M17 in complex with hydroxamic acid-based inhibitor 10s
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0006508 | biological_process | proteolysis |
| A | 0019538 | biological_process | protein metabolic process |
| A | 0030145 | molecular_function | manganese ion binding |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0070006 | molecular_function | metalloaminopeptidase activity |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0006508 | biological_process | proteolysis |
| B | 0019538 | biological_process | protein metabolic process |
| B | 0030145 | molecular_function | manganese ion binding |
| B | 0046872 | molecular_function | metal ion binding |
| B | 0070006 | molecular_function | metalloaminopeptidase activity |
| C | 0005737 | cellular_component | cytoplasm |
| C | 0006508 | biological_process | proteolysis |
| C | 0019538 | biological_process | protein metabolic process |
| C | 0030145 | molecular_function | manganese ion binding |
| C | 0046872 | molecular_function | metal ion binding |
| C | 0070006 | molecular_function | metalloaminopeptidase activity |
| D | 0005737 | cellular_component | cytoplasm |
| D | 0006508 | biological_process | proteolysis |
| D | 0019538 | biological_process | protein metabolic process |
| D | 0030145 | molecular_function | manganese ion binding |
| D | 0046872 | molecular_function | metal ion binding |
| D | 0070006 | molecular_function | metalloaminopeptidase activity |
| E | 0005737 | cellular_component | cytoplasm |
| E | 0006508 | biological_process | proteolysis |
| E | 0019538 | biological_process | protein metabolic process |
| E | 0030145 | molecular_function | manganese ion binding |
| E | 0046872 | molecular_function | metal ion binding |
| E | 0070006 | molecular_function | metalloaminopeptidase activity |
| F | 0005737 | cellular_component | cytoplasm |
| F | 0006508 | biological_process | proteolysis |
| F | 0019538 | biological_process | protein metabolic process |
| F | 0030145 | molecular_function | manganese ion binding |
| F | 0046872 | molecular_function | metal ion binding |
| F | 0070006 | molecular_function | metalloaminopeptidase activity |
| G | 0005737 | cellular_component | cytoplasm |
| G | 0006508 | biological_process | proteolysis |
| G | 0019538 | biological_process | protein metabolic process |
| G | 0030145 | molecular_function | manganese ion binding |
| G | 0046872 | molecular_function | metal ion binding |
| G | 0070006 | molecular_function | metalloaminopeptidase activity |
| H | 0005737 | cellular_component | cytoplasm |
| H | 0006508 | biological_process | proteolysis |
| H | 0019538 | biological_process | protein metabolic process |
| H | 0030145 | molecular_function | manganese ion binding |
| H | 0046872 | molecular_function | metal ion binding |
| H | 0070006 | molecular_function | metalloaminopeptidase activity |
| I | 0005737 | cellular_component | cytoplasm |
| I | 0006508 | biological_process | proteolysis |
| I | 0019538 | biological_process | protein metabolic process |
| I | 0030145 | molecular_function | manganese ion binding |
| I | 0046872 | molecular_function | metal ion binding |
| I | 0070006 | molecular_function | metalloaminopeptidase activity |
| J | 0005737 | cellular_component | cytoplasm |
| J | 0006508 | biological_process | proteolysis |
| J | 0019538 | biological_process | protein metabolic process |
| J | 0030145 | molecular_function | manganese ion binding |
| J | 0046872 | molecular_function | metal ion binding |
| J | 0070006 | molecular_function | metalloaminopeptidase activity |
| K | 0005737 | cellular_component | cytoplasm |
| K | 0006508 | biological_process | proteolysis |
| K | 0019538 | biological_process | protein metabolic process |
| K | 0030145 | molecular_function | manganese ion binding |
| K | 0046872 | molecular_function | metal ion binding |
| K | 0070006 | molecular_function | metalloaminopeptidase activity |
| L | 0005737 | cellular_component | cytoplasm |
| L | 0006508 | biological_process | proteolysis |
| L | 0019538 | biological_process | protein metabolic process |
| L | 0030145 | molecular_function | manganese ion binding |
| L | 0046872 | molecular_function | metal ion binding |
| L | 0070006 | molecular_function | metalloaminopeptidase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 18 |
| Details | binding site for residue 4U6 A 1001 |
| Chain | Residue |
| A | LYS374 |
| A | THR488 |
| A | GLY489 |
| A | LEU492 |
| A | SER554 |
| A | ALA577 |
| A | ZN1002 |
| A | ZN1003 |
| A | CO31004 |
| A | HOH1129 |
| A | ASP379 |
| A | LYS386 |
| A | GLY390 |
| A | MET392 |
| A | PHE398 |
| A | ASP459 |
| A | GLU461 |
| A | LEU487 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | binding site for residue ZN A 1002 |
| Chain | Residue |
| A | LYS374 |
| A | ASP379 |
| A | ASP399 |
| A | GLU461 |
| A | 4U61001 |
| A | ZN1003 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | binding site for residue ZN A 1003 |
| Chain | Residue |
| A | ASP379 |
| A | ASP459 |
| A | GLU461 |
| A | 4U61001 |
| A | ZN1002 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | binding site for residue CO3 A 1004 |
| Chain | Residue |
| A | LYS374 |
| A | ALA460 |
| A | GLY462 |
| A | ARG463 |
| A | LEU487 |
| A | 4U61001 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | binding site for residue 1PE A 1005 |
| Chain | Residue |
| A | TYR103 |
| A | ASN104 |
| A | HIS108 |
| A | LYS320 |
| A | TYR411 |
| A | HOH1136 |
| site_id | AC6 |
| Number of Residues | 3 |
| Details | binding site for residue 1PE A 1006 |
| Chain | Residue |
| A | TYR103 |
| A | GLU316 |
| A | LYS320 |
| site_id | AC7 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 A 1007 |
| Chain | Residue |
| A | ILE101 |
| A | GLU102 |
| A | TYR103 |
| A | ASN104 |
| site_id | AC8 |
| Number of Residues | 16 |
| Details | binding site for residue 4U6 B 1001 |
| Chain | Residue |
| B | LYS374 |
| B | ASP379 |
| B | LYS386 |
| B | GLY390 |
| B | MET392 |
| B | PHE398 |
| B | ASP459 |
| B | GLU461 |
| B | LEU487 |
| B | THR488 |
| B | GLY489 |
| B | LEU492 |
| B | ALA577 |
| B | ZN1002 |
| B | ZN1003 |
| B | CO31004 |
| site_id | AC9 |
| Number of Residues | 6 |
| Details | binding site for residue ZN B 1002 |
| Chain | Residue |
| B | LYS374 |
| B | ASP379 |
| B | ASP399 |
| B | GLU461 |
| B | 4U61001 |
| B | ZN1003 |
| site_id | AD1 |
| Number of Residues | 5 |
| Details | binding site for residue ZN B 1003 |
| Chain | Residue |
| B | ASP379 |
| B | ASP459 |
| B | GLU461 |
| B | 4U61001 |
| B | ZN1002 |
| site_id | AD2 |
| Number of Residues | 6 |
| Details | binding site for residue CO3 B 1004 |
| Chain | Residue |
| B | LYS374 |
| B | ALA460 |
| B | GLY462 |
| B | ARG463 |
| B | LEU487 |
| B | 4U61001 |
| site_id | AD3 |
| Number of Residues | 3 |
| Details | binding site for residue 1PE B 1005 |
| Chain | Residue |
| B | TYR103 |
| B | LYS320 |
| B | TYR411 |
| site_id | AD4 |
| Number of Residues | 6 |
| Details | binding site for residue SO4 B 1006 |
| Chain | Residue |
| A | SER435 |
| A | LYS436 |
| B | SER435 |
| B | LYS436 |
| C | SER435 |
| C | LYS436 |
| site_id | AD5 |
| Number of Residues | 16 |
| Details | binding site for residue 4U6 C 1001 |
| Chain | Residue |
| C | THR488 |
| C | GLY489 |
| C | LEU492 |
| C | ALA577 |
| C | ZN1002 |
| C | ZN1003 |
| C | CO31004 |
| C | LYS374 |
| C | ASP379 |
| C | LYS386 |
| C | GLY390 |
| C | MET392 |
| C | PHE398 |
| C | ASP459 |
| C | GLU461 |
| C | LEU487 |
| site_id | AD6 |
| Number of Residues | 6 |
| Details | binding site for residue ZN C 1002 |
| Chain | Residue |
| C | LYS374 |
| C | ASP379 |
| C | ASP399 |
| C | GLU461 |
| C | 4U61001 |
| C | ZN1003 |
| site_id | AD7 |
| Number of Residues | 5 |
| Details | binding site for residue ZN C 1003 |
| Chain | Residue |
| C | ASP379 |
| C | ASP459 |
| C | GLU461 |
| C | 4U61001 |
| C | ZN1002 |
| site_id | AD8 |
| Number of Residues | 6 |
| Details | binding site for residue CO3 C 1004 |
| Chain | Residue |
| C | LYS374 |
| C | ALA460 |
| C | GLY462 |
| C | ARG463 |
| C | LEU487 |
| C | 4U61001 |
| site_id | AD9 |
| Number of Residues | 5 |
| Details | binding site for residue 1PE C 1005 |
| Chain | Residue |
| C | TYR103 |
| C | GLU316 |
| C | GLN319 |
| C | LYS320 |
| C | 1PE1006 |
| site_id | AE1 |
| Number of Residues | 4 |
| Details | binding site for residue 1PE C 1006 |
| Chain | Residue |
| C | TYR103 |
| C | ASN104 |
| C | TYR411 |
| C | 1PE1005 |
| site_id | AE2 |
| Number of Residues | 15 |
| Details | binding site for residue 4U6 D 1001 |
| Chain | Residue |
| D | LYS374 |
| D | ASP379 |
| D | LYS386 |
| D | GLY390 |
| D | MET392 |
| D | ASP459 |
| D | GLU461 |
| D | LEU487 |
| D | THR488 |
| D | GLY489 |
| D | LEU492 |
| D | ALA577 |
| D | ZN1002 |
| D | ZN1003 |
| D | CO31004 |
| site_id | AE3 |
| Number of Residues | 6 |
| Details | binding site for residue ZN D 1002 |
| Chain | Residue |
| D | LYS374 |
| D | ASP379 |
| D | ASP399 |
| D | GLU461 |
| D | 4U61001 |
| D | ZN1003 |
| site_id | AE4 |
| Number of Residues | 5 |
| Details | binding site for residue ZN D 1003 |
| Chain | Residue |
| D | ASP379 |
| D | ASP459 |
| D | GLU461 |
| D | 4U61001 |
| D | ZN1002 |
| site_id | AE5 |
| Number of Residues | 6 |
| Details | binding site for residue CO3 D 1004 |
| Chain | Residue |
| D | LYS374 |
| D | ALA460 |
| D | GLY462 |
| D | ARG463 |
| D | LEU487 |
| D | 4U61001 |
| site_id | AE6 |
| Number of Residues | 2 |
| Details | binding site for residue 1PE D 1005 |
| Chain | Residue |
| D | GLU316 |
| D | LYS320 |
| site_id | AE7 |
| Number of Residues | 6 |
| Details | binding site for residue 1PE D 1006 |
| Chain | Residue |
| D | TYR103 |
| D | ASN104 |
| D | HIS108 |
| D | PHE289 |
| D | LYS320 |
| D | TYR411 |
| site_id | AE8 |
| Number of Residues | 6 |
| Details | binding site for residue SO4 D 1007 |
| Chain | Residue |
| D | SER435 |
| D | LYS436 |
| E | SER435 |
| E | LYS436 |
| F | SER435 |
| F | LYS436 |
| site_id | AE9 |
| Number of Residues | 14 |
| Details | binding site for residue 4U6 E 1001 |
| Chain | Residue |
| E | LYS374 |
| E | ASP379 |
| E | LYS386 |
| E | GLY390 |
| E | MET392 |
| E | ASP459 |
| E | GLU461 |
| E | LEU487 |
| E | THR488 |
| E | GLY489 |
| E | LEU492 |
| E | ZN1002 |
| E | ZN1003 |
| E | CO31004 |
| site_id | AF1 |
| Number of Residues | 6 |
| Details | binding site for residue ZN E 1002 |
| Chain | Residue |
| E | LYS374 |
| E | ASP379 |
| E | ASP399 |
| E | GLU461 |
| E | 4U61001 |
| E | ZN1003 |
| site_id | AF2 |
| Number of Residues | 5 |
| Details | binding site for residue ZN E 1003 |
| Chain | Residue |
| E | ASP379 |
| E | ASP459 |
| E | GLU461 |
| E | 4U61001 |
| E | ZN1002 |
| site_id | AF3 |
| Number of Residues | 6 |
| Details | binding site for residue CO3 E 1004 |
| Chain | Residue |
| E | LYS374 |
| E | ALA460 |
| E | GLY462 |
| E | ARG463 |
| E | LEU487 |
| E | 4U61001 |
| site_id | AF4 |
| Number of Residues | 4 |
| Details | binding site for residue 1PE E 1005 |
| Chain | Residue |
| E | TYR103 |
| E | GLU316 |
| E | GLN319 |
| E | LYS320 |
| site_id | AF5 |
| Number of Residues | 5 |
| Details | binding site for residue 1PE E 1006 |
| Chain | Residue |
| E | TYR103 |
| E | HIS108 |
| E | LYS320 |
| E | TYR411 |
| E | HOH1216 |
| site_id | AF6 |
| Number of Residues | 18 |
| Details | binding site for residue 4U6 F 1001 |
| Chain | Residue |
| F | LYS374 |
| F | ASP379 |
| F | LYS386 |
| F | GLY390 |
| F | SER391 |
| F | MET392 |
| F | PHE398 |
| F | ASP459 |
| F | GLU461 |
| F | LEU487 |
| F | THR488 |
| F | GLY489 |
| F | LEU492 |
| F | ALA577 |
| F | ZN1002 |
| F | ZN1003 |
| F | CO31004 |
| F | HOH1144 |
| site_id | AF7 |
| Number of Residues | 6 |
| Details | binding site for residue ZN F 1002 |
| Chain | Residue |
| F | LYS374 |
| F | ASP379 |
| F | ASP399 |
| F | GLU461 |
| F | 4U61001 |
| F | ZN1003 |
| site_id | AF8 |
| Number of Residues | 5 |
| Details | binding site for residue ZN F 1003 |
| Chain | Residue |
| F | ASP379 |
| F | ASP459 |
| F | GLU461 |
| F | 4U61001 |
| F | ZN1002 |
| site_id | AF9 |
| Number of Residues | 7 |
| Details | binding site for residue CO3 F 1004 |
| Chain | Residue |
| F | LYS374 |
| F | ALA460 |
| F | GLU461 |
| F | GLY462 |
| F | ARG463 |
| F | LEU487 |
| F | 4U61001 |
| site_id | AG1 |
| Number of Residues | 5 |
| Details | binding site for residue 1PE F 1005 |
| Chain | Residue |
| F | TYR103 |
| F | ASN104 |
| F | HIS108 |
| F | LYS320 |
| F | TYR411 |
| site_id | AG2 |
| Number of Residues | 6 |
| Details | binding site for residue 1PE F 1006 |
| Chain | Residue |
| F | TYR103 |
| F | ASN104 |
| F | GLU316 |
| F | GLN319 |
| F | LYS320 |
| F | SO41007 |
| site_id | AG3 |
| Number of Residues | 5 |
| Details | binding site for residue SO4 F 1007 |
| Chain | Residue |
| F | GLU102 |
| F | TYR103 |
| F | ASN104 |
| F | 1PE1006 |
| F | HOH1142 |
| site_id | AG4 |
| Number of Residues | 15 |
| Details | binding site for residue 4U6 G 1001 |
| Chain | Residue |
| G | LYS374 |
| G | ASP379 |
| G | LYS386 |
| G | GLY390 |
| G | MET392 |
| G | ASP459 |
| G | GLU461 |
| G | LEU487 |
| G | THR488 |
| G | GLY489 |
| G | LEU492 |
| G | ALA577 |
| G | ZN1002 |
| G | ZN1003 |
| G | CO31004 |
| site_id | AG5 |
| Number of Residues | 6 |
| Details | binding site for residue ZN G 1002 |
| Chain | Residue |
| G | LYS374 |
| G | ASP379 |
| G | ASP399 |
| G | GLU461 |
| G | 4U61001 |
| G | ZN1003 |
| site_id | AG6 |
| Number of Residues | 5 |
| Details | binding site for residue ZN G 1003 |
| Chain | Residue |
| G | ASP379 |
| G | ASP459 |
| G | GLU461 |
| G | 4U61001 |
| G | ZN1002 |
| site_id | AG7 |
| Number of Residues | 6 |
| Details | binding site for residue CO3 G 1004 |
| Chain | Residue |
| G | LYS374 |
| G | ALA460 |
| G | GLY462 |
| G | ARG463 |
| G | LEU487 |
| G | 4U61001 |
| site_id | AG8 |
| Number of Residues | 4 |
| Details | binding site for residue 1PE G 1005 |
| Chain | Residue |
| G | TYR103 |
| G | ASN104 |
| G | HIS108 |
| G | TYR411 |
| site_id | AG9 |
| Number of Residues | 9 |
| Details | binding site for residue 1PE G 1006 |
| Chain | Residue |
| A | TYR115 |
| A | ASN122 |
| A | GLU124 |
| A | TYR270 |
| G | TYR115 |
| G | ASN122 |
| G | TYR270 |
| G | 1PE1007 |
| G | HOH1140 |
| site_id | AH1 |
| Number of Residues | 5 |
| Details | binding site for residue 1PE G 1007 |
| Chain | Residue |
| A | ASN122 |
| G | ASN122 |
| G | TYR270 |
| G | 1PE1006 |
| G | HOH1154 |
| site_id | AH2 |
| Number of Residues | 6 |
| Details | binding site for residue SO4 G 1008 |
| Chain | Residue |
| G | SER435 |
| G | LYS436 |
| H | SER435 |
| H | LYS436 |
| I | SER435 |
| I | LYS436 |
| site_id | AH3 |
| Number of Residues | 15 |
| Details | binding site for residue 4U6 H 1001 |
| Chain | Residue |
| H | LYS374 |
| H | ASP379 |
| H | LYS386 |
| H | GLY390 |
| H | MET392 |
| H | PHE398 |
| H | ASP459 |
| H | GLU461 |
| H | LEU487 |
| H | GLY489 |
| H | LEU492 |
| H | ALA577 |
| H | ZN1002 |
| H | ZN1003 |
| H | CO31004 |
| site_id | AH4 |
| Number of Residues | 6 |
| Details | binding site for residue ZN H 1002 |
| Chain | Residue |
| H | LYS374 |
| H | ASP379 |
| H | ASP399 |
| H | GLU461 |
| H | 4U61001 |
| H | ZN1003 |
| site_id | AH5 |
| Number of Residues | 5 |
| Details | binding site for residue ZN H 1003 |
| Chain | Residue |
| H | ASP379 |
| H | ASP459 |
| H | GLU461 |
| H | 4U61001 |
| H | ZN1002 |
| site_id | AH6 |
| Number of Residues | 7 |
| Details | binding site for residue CO3 H 1004 |
| Chain | Residue |
| H | LYS374 |
| H | ALA460 |
| H | GLU461 |
| H | GLY462 |
| H | ARG463 |
| H | LEU487 |
| H | 4U61001 |
| site_id | AH7 |
| Number of Residues | 3 |
| Details | binding site for residue 1PE H 1005 |
| Chain | Residue |
| H | TYR103 |
| H | GLU316 |
| H | LYS320 |
| site_id | AH8 |
| Number of Residues | 17 |
| Details | binding site for residue 4U6 I 1001 |
| Chain | Residue |
| I | LYS374 |
| I | ASP379 |
| I | LYS386 |
| I | GLY390 |
| I | SER391 |
| I | MET392 |
| I | PHE398 |
| I | ASP459 |
| I | GLU461 |
| I | LEU487 |
| I | THR488 |
| I | GLY489 |
| I | LEU492 |
| I | ALA577 |
| I | ZN1002 |
| I | ZN1003 |
| I | CO31004 |
| site_id | AH9 |
| Number of Residues | 6 |
| Details | binding site for residue ZN I 1002 |
| Chain | Residue |
| I | LYS374 |
| I | ASP379 |
| I | ASP399 |
| I | GLU461 |
| I | 4U61001 |
| I | ZN1003 |
| site_id | AI1 |
| Number of Residues | 5 |
| Details | binding site for residue ZN I 1003 |
| Chain | Residue |
| I | ASP379 |
| I | ASP459 |
| I | GLU461 |
| I | 4U61001 |
| I | ZN1002 |
| site_id | AI2 |
| Number of Residues | 6 |
| Details | binding site for residue CO3 I 1004 |
| Chain | Residue |
| I | LYS374 |
| I | ALA460 |
| I | GLY462 |
| I | ARG463 |
| I | LEU487 |
| I | 4U61001 |
| site_id | AI3 |
| Number of Residues | 3 |
| Details | binding site for residue 1PE I 1005 |
| Chain | Residue |
| I | TYR103 |
| I | GLU316 |
| I | LYS320 |
| site_id | AI4 |
| Number of Residues | 4 |
| Details | binding site for residue 1PE I 1006 |
| Chain | Residue |
| I | TYR103 |
| I | HIS108 |
| I | LYS320 |
| I | TYR411 |
| site_id | AI5 |
| Number of Residues | 15 |
| Details | binding site for residue 4U6 J 1001 |
| Chain | Residue |
| J | LYS374 |
| J | ASP379 |
| J | LYS386 |
| J | GLY390 |
| J | MET392 |
| J | ASP459 |
| J | GLU461 |
| J | LEU487 |
| J | THR488 |
| J | GLY489 |
| J | LEU492 |
| J | ALA577 |
| J | ZN1002 |
| J | ZN1003 |
| J | CO31004 |
| site_id | AI6 |
| Number of Residues | 6 |
| Details | binding site for residue ZN J 1002 |
| Chain | Residue |
| J | LYS374 |
| J | ASP379 |
| J | ASP399 |
| J | GLU461 |
| J | 4U61001 |
| J | ZN1003 |
| site_id | AI7 |
| Number of Residues | 5 |
| Details | binding site for residue ZN J 1003 |
| Chain | Residue |
| J | ASP379 |
| J | ASP459 |
| J | GLU461 |
| J | 4U61001 |
| J | ZN1002 |
| site_id | AI8 |
| Number of Residues | 7 |
| Details | binding site for residue CO3 J 1004 |
| Chain | Residue |
| J | LYS374 |
| J | ALA460 |
| J | GLU461 |
| J | GLY462 |
| J | ARG463 |
| J | LEU487 |
| J | 4U61001 |
| site_id | AI9 |
| Number of Residues | 7 |
| Details | binding site for residue 1PE J 1005 |
| Chain | Residue |
| J | TYR103 |
| J | ASN104 |
| J | HIS108 |
| J | PHE289 |
| J | LYS320 |
| J | TYR411 |
| J | HOH1119 |
| site_id | AJ1 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 J 1006 |
| Chain | Residue |
| J | GLU102 |
| J | TYR103 |
| J | ASN104 |
| site_id | AJ2 |
| Number of Residues | 16 |
| Details | binding site for residue 4U6 K 1001 |
| Chain | Residue |
| K | LYS374 |
| K | ASP379 |
| K | LYS386 |
| K | GLY390 |
| K | MET392 |
| K | ASP459 |
| K | GLU461 |
| K | LEU487 |
| K | THR488 |
| K | GLY489 |
| K | LEU492 |
| K | ALA577 |
| K | ZN1002 |
| K | ZN1003 |
| K | CO31004 |
| K | HOH1127 |
| site_id | AJ3 |
| Number of Residues | 7 |
| Details | binding site for residue ZN K 1002 |
| Chain | Residue |
| K | LYS374 |
| K | ASP379 |
| K | ASP399 |
| K | GLU461 |
| K | 4U61001 |
| K | ZN1003 |
| K | HOH1127 |
| site_id | AJ4 |
| Number of Residues | 5 |
| Details | binding site for residue ZN K 1003 |
| Chain | Residue |
| K | ASP379 |
| K | ASP459 |
| K | GLU461 |
| K | 4U61001 |
| K | ZN1002 |
| site_id | AJ5 |
| Number of Residues | 6 |
| Details | binding site for residue CO3 K 1004 |
| Chain | Residue |
| K | LYS374 |
| K | ALA460 |
| K | GLY462 |
| K | ARG463 |
| K | LEU487 |
| K | 4U61001 |
| site_id | AJ6 |
| Number of Residues | 3 |
| Details | binding site for residue 1PE K 1005 |
| Chain | Residue |
| K | TYR103 |
| K | HIS108 |
| K | TYR411 |
| site_id | AJ7 |
| Number of Residues | 6 |
| Details | binding site for residue SO4 K 1006 |
| Chain | Residue |
| I | PHE156 |
| I | LYS164 |
| K | TYR176 |
| K | MET177 |
| K | PHE178 |
| K | SER184 |
| site_id | AJ8 |
| Number of Residues | 15 |
| Details | binding site for residue 4U6 L 1001 |
| Chain | Residue |
| L | LYS374 |
| L | ASP379 |
| L | LYS386 |
| L | GLY390 |
| L | MET392 |
| L | ASP459 |
| L | GLU461 |
| L | LEU487 |
| L | THR488 |
| L | GLY489 |
| L | LEU492 |
| L | ALA577 |
| L | ZN1002 |
| L | ZN1003 |
| L | CO31004 |
| site_id | AJ9 |
| Number of Residues | 6 |
| Details | binding site for residue ZN L 1002 |
| Chain | Residue |
| L | LYS374 |
| L | ASP379 |
| L | ASP399 |
| L | GLU461 |
| L | 4U61001 |
| L | ZN1003 |
| site_id | AK1 |
| Number of Residues | 5 |
| Details | binding site for residue ZN L 1003 |
| Chain | Residue |
| L | ASP379 |
| L | ASP459 |
| L | GLU461 |
| L | 4U61001 |
| L | ZN1002 |
| site_id | AK2 |
| Number of Residues | 7 |
| Details | binding site for residue CO3 L 1004 |
| Chain | Residue |
| L | LYS374 |
| L | ALA460 |
| L | GLU461 |
| L | GLY462 |
| L | ARG463 |
| L | LEU487 |
| L | 4U61001 |
| site_id | AK3 |
| Number of Residues | 5 |
| Details | binding site for residue 1PE L 1005 |
| Chain | Residue |
| L | TYR103 |
| L | ASN104 |
| L | LYS320 |
| L | TYR411 |
| L | HOH1163 |
| site_id | AK4 |
| Number of Residues | 6 |
| Details | binding site for residue SO4 L 1006 |
| Chain | Residue |
| J | SER435 |
| J | LYS436 |
| K | SER435 |
| K | LYS436 |
| L | SER435 |
| L | LYS436 |
Functional Information from PROSITE/UniProt
| site_id | PS00631 |
| Number of Residues | 8 |
| Details | CYTOSOL_AP Cytosol aminopeptidase signature. NTDAEGRL |
| Chain | Residue | Details |
| A | ASN457-LEU464 |
