Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0003908 | molecular_function | methylated-DNA-[protein]-cysteine S-methyltransferase activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0006281 | biological_process | DNA repair |
| A | 0006307 | biological_process | DNA alkylation repair |
| A | 0006974 | biological_process | DNA damage response |
| A | 0008168 | molecular_function | methyltransferase activity |
| A | 0016740 | molecular_function | transferase activity |
| A | 0032259 | biological_process | methylation |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | binding site for residue GOL A 201 |
| Chain | Residue |
| A | GLY12 |
| A | TYR13 |
| A | CYS29 |
| A | ASP30 |
| A | HOH316 |
| site_id | AC2 |
| Number of Residues | 7 |
| Details | binding site for residue GOL A 202 |
| Chain | Residue |
| A | GLU44 |
| A | PHE45 |
| A | HOH360 |
| A | LYS18 |
| A | PHE23 |
| A | SER41 |
| A | PHE42 |
| site_id | AC3 |
| Number of Residues | 3 |
| Details | binding site for residue NO3 A 203 |
| Chain | Residue |
| A | ARG72 |
| A | HOH325 |
| A | HOH417 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | binding site for residue NO3 A 204 |
| Chain | Residue |
| A | VAL32 |
| A | ARG37 |
| A | LYS148 |
| A | HOH367 |
| A | HOH381 |
| site_id | AC5 |
| Number of Residues | 7 |
| Details | binding site for residue NO3 A 205 |
| Chain | Residue |
| A | PRO70 |
| A | THR89 |
| A | TYR90 |
| A | LYS91 |
| A | PRO101 |
| A | ALA124 |
| A | GLU125 |
Functional Information from PROSITE/UniProt
| site_id | PS00374 |
| Number of Residues | 7 |
| Details | MGMT Methylated-DNA--protein-cysteine methyltransferase active site. IPCHRVI |
| Chain | Residue | Details |
| A | ILE117-ILE123 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | Active site: {"description":"Nucleophile; methyl group acceptor","evidences":[{"source":"HAMAP-Rule","id":"MF_00772","evidenceCode":"ECO:0000255"}]} |
