4ZXI

Crystal Structure of holo-AB3403 a four domain nonribosomal peptide synthetase bound to AMP and Glycine

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003824	molecular_function	catalytic activity
A	0005737	cellular_component	cytoplasm
A	0009058	biological_process	biosynthetic process
A	0031177	molecular_function	phosphopantetheine binding
A	0043041	biological_process	amino acid activation for nonribosomal peptide biosynthetic process
A	0044550	biological_process	secondary metabolite biosynthetic process

Functional Information from PDB Data

site_id	AC1
Number of Residues	9
Details	binding site for residue PNS A 1401

Chain	Residue
A	GLY23
A	ILE27
A	TYR37
A	THR298
A	SER334
A	VAL337
A	ARG344
A	ASN349
A	SER1006

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site_id	AC2
Number of Residues	10
Details	binding site for residue GLY A 1402

Chain	Residue
A	PHE669
A	ASP670
A	GLY739
A	GLY762
A	PRO763
A	THR764
A	VAL768
A	LYS952
A	AMP1403
A	MG1406

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site_id	AC3
Number of Residues	14
Details	binding site for residue AMP A 1403

Chain	Residue
A	THR625
A	SER626
A	GLY739
A	GLU740
A	ASN759
A	VAL760
A	TYR761
A	PRO763
A	ASP849
A	HIS861
A	ARG864
A	LYS952
A	GLY1402
A	MG1406

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site_id	AC4
Number of Residues	5
Details	binding site for residue XP4 A 1404

Chain	Residue
A	ILE56
A	LEU59
A	TYR137
A	LEU157
A	VAL160

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site_id	AC5
Number of Residues	3
Details	binding site for residue NI A 1405

Chain	Residue
A	GLY-1
A	HIS0
A	HIS524

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site_id	AC6
Number of Residues	3
Details	binding site for residue MG A 1406

Chain	Residue
A	THR764
A	GLY1402
A	AMP1403

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