Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004190 | molecular_function | aspartic-type endopeptidase activity |
| A | 0006508 | biological_process | proteolysis |
| A | 0016020 | cellular_component | membrane |
| B | 0004190 | molecular_function | aspartic-type endopeptidase activity |
| B | 0006508 | biological_process | proteolysis |
| B | 0016020 | cellular_component | membrane |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 13 |
| Details | binding site for residue 4RZ A 401 |
| Chain | Residue |
| A | SER10 |
| A | SER229 |
| A | GLY230 |
| A | THR232 |
| A | HOH618 |
| A | GLY11 |
| A | GLN12 |
| A | GLY13 |
| A | ASP32 |
| A | GLY34 |
| A | TYR71 |
| A | TRP115 |
| A | ASP228 |
| site_id | AC2 |
| Number of Residues | 8 |
| Details | binding site for residue GOL A 402 |
| Chain | Residue |
| A | ASP318 |
| A | HOH513 |
| A | HOH567 |
| A | HOH729 |
| B | SER58 |
| B | THR59 |
| B | ARG61 |
| B | ARG96 |
| site_id | AC3 |
| Number of Residues | 13 |
| Details | binding site for residue 4RZ B 401 |
| Chain | Residue |
| B | SER10 |
| B | GLY11 |
| B | GLN12 |
| B | GLY13 |
| B | ASP32 |
| B | GLY34 |
| B | TYR71 |
| B | TRP115 |
| B | ASP228 |
| B | SER229 |
| B | GLY230 |
| B | THR232 |
| B | HOH544 |
| site_id | AC4 |
| Number of Residues | 8 |
| Details | binding site for residue GOL B 402 |
| Chain | Residue |
| A | SER58 |
| A | THR59 |
| A | ARG61 |
| A | ARG96 |
| B | ASP318 |
| B | HOH528 |
| B | HOH596 |
| B | HOH635 |
Functional Information from PROSITE/UniProt
| site_id | PS00141 |
| Number of Residues | 12 |
| Details | ASP_PROTEASE Eukaryotic and viral aspartyl proteases active site. ILVDTGSSNFAV |
| Chain | Residue | Details |
| A | ILE29-VAL40 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 682 |
| Details | Domain: {"description":"Peptidase A1","evidences":[{"source":"PROSITE-ProRule","id":"PRU01103","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | Active site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU10094","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 14 |
| Details | Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"PubMed","id":"17425515","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"19011241","evidenceCode":"ECO:0000269"}]} |
| site_id | SWS_FT_FI4 |
| Number of Residues | 8 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"evidenceCode":"ECO:0000255"}]} |
