4ZPU
The structure of DLP12 endolysin exhibits likely active and inactive conformations.
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003796 | molecular_function | lysozyme activity |
| A | 0009253 | biological_process | peptidoglycan catabolic process |
| A | 0016998 | biological_process | cell wall macromolecule catabolic process |
| A | 0044659 | biological_process | viral release from host cell by cytolysis |
| B | 0003796 | molecular_function | lysozyme activity |
| B | 0009253 | biological_process | peptidoglycan catabolic process |
| B | 0016998 | biological_process | cell wall macromolecule catabolic process |
| B | 0044659 | biological_process | viral release from host cell by cytolysis |
| C | 0003796 | molecular_function | lysozyme activity |
| C | 0009253 | biological_process | peptidoglycan catabolic process |
| C | 0016998 | biological_process | cell wall macromolecule catabolic process |
| C | 0044659 | biological_process | viral release from host cell by cytolysis |
| D | 0003796 | molecular_function | lysozyme activity |
| D | 0009253 | biological_process | peptidoglycan catabolic process |
| D | 0016998 | biological_process | cell wall macromolecule catabolic process |
| D | 0044659 | biological_process | viral release from host cell by cytolysis |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 3 |
| Details | binding site for residue ACT A 201 |
| Chain | Residue |
| A | GLY57 |
| A | LYS58 |
| A | ILE60 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | binding site for residue ACT B 201 |
| Chain | Residue |
| B | GLY54 |
| B | HIS55 |
| B | THR56 |
| B | TYR107 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | binding site for residue ACT C 201 |
| Chain | Residue |
| C | LYS58 |
| C | ASP59 |
| C | ILE60 |
| C | LEU62 |
| B | TYR140 |
| C | GLY57 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | binding site for residue FMT C 202 |
| Chain | Residue |
| C | GLY54 |
| C | HIS55 |
| C | THR56 |
| C | TYR107 |
| site_id | AC5 |
| Number of Residues | 3 |
| Details | binding site for residue FMT C 203 |
| Chain | Residue |
| A | LYS58 |
| C | ARG137 |
| C | TRP138 |
| site_id | AC6 |
| Number of Residues | 2 |
| Details | binding site for residue ACT D 201 |
| Chain | Residue |
| D | THR56 |
| D | ASP78 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 4 |
| Details | Active site: {"description":"Proton donor","evidences":[{"evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | Active site: {"description":"Nucleophile","evidences":[{"evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
